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Search Thermo Fisher Scientific
Immunogen sequence: DIGSKLVVWR ALQALTGPRK LLFLSPDLEL NSSSSHNTLR PAPRGSAQES AVRPRRMVEP LEDRRQENFF CGPPEKSYAK LVFMSTSSGS LWNLHAIHSM CRMEQDQIR
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 66%.
DISP2, also known as dispatched homolog 2, is a protein that plays a critical role in the regulation of the hedgehog signaling pathway. It is involved in the transport and release of hedgehog ligands, which are important for cellular differentiation and tissue development. Mutations in the DISP2 gene have been associated with various developmental disorders, including holoprosencephaly and cleft lip and palate. DISP2 is also being studied as a potential therapeutic target in cancer, as the hedgehog pathway is frequently dysregulated in various types of tumors
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dispatched B; dispatched homolog 2; Protein dispatched homolog 2
Gene Aliases: C15orf36; DISP2; DISPB; HsT16908; KIAA1742; LINC00594
UniProt ID: (Human) A7MBM2
Entrez Gene ID: (Human) 85455
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