Product References
Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model.
NPJ vaccines
Ludwig J,Scally SW,Costa G,Hoffmann S,Murugan R,Lossin J,Prieto K,Obraztsova A,Lobeto N,Franke-Fayard B,Janse CJ,Lebas C,Collin N,Binter S,Kellam P,Levashina EA,Wardemann H,Julien JP
48-5902-82 was used in Flow cytometry/Cell sorting to highlight the power of rational vaccine design to generate a highly efficacious second-generation anti-infective malaria vaccine candidate and provides the basis for its further development.
Fri Apr 07 00:00:00 EDT 2023
Toll-like receptor mediated inflammation directs B cells towards protective antiviral extrafollicular responses.
Nature communications
Lam JH,Baumgarth N
48-5902-82 was used in Flow cytometry/Cell sorting to show that influenza infection rapidly induces EFRs, generating protective antibodies via Toll-like receptor (TLR)-mediated mechanisms that are both B cell intrinsic and extrinsic.
Wed Jul 05 00:00:00 EDT 2023
RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
iScience
Liang Q,Wang Y,Zhang S,Sun J,Sun W,Li J,Liu Y,Li M,Cheng L,Jiang Y,Wang R,Zhang R,Yang Z,Ren Y,Chen P,Gao P,Yan H,Zhang Z,Zhang Q,Shi X,Wang J,Liu W,Wang X,Ying B,Zhao J,Qi H,Zhang L
48-5902-82 was used in Flow cytometry/Cell sorting to demonstrate that the RBD trimer mRNA vaccine serves as a promising vaccine candidate against SARS-CoV-2 variants and beyond.
Fri Apr 15 00:00:00 EDT 2022
Rapid and sensitive single-cell RNA sequencing with SHERRY2.
BMC biology
Di L,Liu B,Lyu Y,Zhao S,Pang Y,Zhang C,Wang J,Qi H,Shen J,Huang Y
48-5902-82 was used in Flow cytometry/Cell sorting to show that SHERRY2 is able to provide high sensitivity, high accuracy, and high throughput for those applications that require a high number of genes identified in each cell.
Fri Sep 30 00:00:00 EDT 2022
Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens.
Cell reports. Medicine
Kraft JC,Pham MN,Shehata L,Brinkkemper M,Boyoglu-Barnum S,Sprouse KR,Walls AC,Cheng S,Murphy M,Pettie D,Ahlrichs M,Sydeman C,Johnson M,Blackstone A,Ellis D,Ravichandran R,Fiala B,Wrenn S,Miranda M,Sliepen K,Brouwer PJM,Antanasijevic A,Veesler D,Ward AB,Kanekiyo M,Pepper M,Sanders RW,King NP
48-5902-82 was used in Flow cytometry/Cell sorting to define relationships between anti-scaffold and antigen-specific antibody responses elicited by protein nanoparticle immunogens.
Tue Oct 18 00:00:00 EDT 2022
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.
Cell
Rodda LB,Netland J,Shehata L,Pruner KB,Morawski PA,Thouvenel CD,Takehara KK,Eggenberger J,Hemann EA,Waterman HR,Fahning ML,Chen Y,Hale M,Rathe J,Stokes C,Wrenn S,Fiala B,Carter L,Hamerman JA,King NP,Gale M,Campbell DJ,Rawlings DJ,Pepper M
48-5902 was used in Flow cytometry/Cell sorting to perform a longitudinal assessment of individuals recovered from mild COVID-19 to determine whether they develop and sustain multifaceted SARS-CoV-2-specific immunological memory.
Thu Jan 07 00:00:00 EST 2021
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
48-5902-82 was used in Flow Cytometry to elucidate the molecular mechanisms regulating T follicular helper cells.
Thu Apr 01 00:00:00 EDT 2021
Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors.
The EMBO journal
Wang X,Ray R,Kratochvil S,Melzi E,Lin YC,Giguere S,Xu L,Warner J,Cheon D,Liguori A,Groschel B,Phelps N,Adachi Y,Tingle R,Wu L,Crotty S,Kirsch KH,Nair U,Schief WR,Batista FD
48-5902 was used in Flow cytometry/Cell sorting to report a one-step CRISPR/Cas9 KI methodology to combine the insertion of human germline immunoglobulin heavy and light chains at their endogenous loci in mice.
Fri Jan 15 00:00:00 EST 2021
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.
Cell
Walls AC,Fiala B,Schäfer A,Wrenn S,Pham MN,Murphy M,Tse LV,Shehata L,O'Connor MA,Chen C,Navarro MJ,Miranda MC,Pettie D,Ravichandran R,Kraft JC,Ogohara C,Palser A,Chalk S,Lee EC,Guerriero K,Kepl E,Chow CM,Sydeman C,Hodge EA,Brown B,Fuller JT,Dinnon KH,Gralinski LE,Leist SR,Gully KL,Lewis TB,Guttman M,Chu HY,Lee KK,Fuller DH,Baric RS,Kellam P,Carter L,Pepper M,Sheahan TP,Veesler D,King NP
48-5902 was used in Flow cytometry/Cell sorting to develop a structure-based design of non-particle immunogens to elicit protective antibody responses against SARS-CoV-2 in mice.
Wed Nov 25 00:00:00 EST 2020
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Cell metabolism
Rosser EC,Piper CJM,Matei DE,Blair PA,Rendeiro AF,Orford M,Alber DG,Krausgruber T,Catalan D,Klein N,Manson JJ,Drozdov I,Bock C,Wedderburn LR,Eaton S,Mauri C
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Immunohistochemistry
Tue Apr 07 00:00:00 EDT 2020
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
Cell host & microbe
McNamara HA,Idris AH,Sutton HJ,Vistein R,Flynn BJ,Cai Y,Wiehe K,Lyke KE,Chatterjee D,Kc N,Chakravarty S,Lee Sim BK,Hoffman SL,Bonsignori M,Seder RA,Cockburn IA
48-5902 was used in Flow cytometry/Cell sorting to suggest that antibody feedback drives the diversification of immune responses and that vaccination for malaria will require targeting multiple antigens.
Wed Oct 07 00:00:00 EDT 2020
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2.
bioRxiv : the preprint server for biology
Walls AC,Fiala B,Schäfer A,Wrenn S,Pham MN,Murphy M,Tse LV,Shehata L,O'Connor MA,Chen C,Navarro MJ,Miranda MC,Pettie D,Ravichandran R,Kraft JC,Ogohara C,Palser A,Chalk S,Lee EC,Kepl E,Chow CM,Sydeman C,Hodge EA,Brown B,Fuller JT,Dinnon KH,Gralinski LE,Leist SR,Gully KL,Lewis TB,Guttman M,Chu HY,Lee KK,Fuller DH,Baric RS,Kellam P,Carter L,Pepper M,Sheahan TP,Veesler D,King NP
48-5902-82 was used in Flow Cytometry to highlight the utility of robust antigen display platforms for inducing potent neutralizing antibody responses and launch cGMP manufacturing efforts to advance the lead RBD nanoparticle vaccine into the clinic.
Wed Aug 12 00:00:00 EDT 2020
A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation.
Immunity
Vacchio MS,Ciucci T,Gao Y,Watanabe M,Balmaceno-Criss M,McGinty MT,Huang A,Xiao Q,McConkey C,Zhao Y,Shetty J,Tran B,Pepper M,Vahedi G,Jenkins MK,McGavern DB,Bosselut R
48-5902-82 was used in Flow Cytometry to identify a transcriptional program that links the CD4+ lineage with Tfh differentiation, a limiting factor for efficient B cell responses.
Tue Sep 17 00:00:00 EDT 2019
Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Cell reports
Parks KR,MacCamy AJ,Trichka J,Gray M,Weidle C,Borst AJ,Khechaduri A,Takushi B,Agrawal P,Guenaga J,Wyatt RT,Coler R,Seaman M,LaBranche C,Montefiori DC,Veesler D,Pancera M,McGuire A,Stamatatos L
48-5902 was used in Flow cytometry/Cell sorting to report on a two-step immunization scheme that leads to the maturation of VRC01-like antibodies capable of accommodating the N276 glycan and displaying autologous tier 2 neutralizing activities.
Tue Dec 03 00:00:00 EST 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
48-5902-82 was used in Flow Cytometry to report a M cell-B cell antigen-specific transporting pathway in PP that is independent of DC. We propose that this antigen transporting pathway has a critical role in gut IgA responses, and should be taken into account when developing mucosal vaccines.
Mon Jun 03 00:00:00 EDT 2019
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
48-5902-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
αv Integrins regulate germinal center B cell responses through noncanonical autophagy.
The Journal of clinical investigation
Raso F,Sagadiev S,Du S,Gage E,Arkatkar T,Metzler G,Stuart LM,Orr MT,Rawlings DJ,Jackson SW,Lacy-Hulbert A,Acharya M
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Fri Aug 31 00:00:00 EDT 2018
Role of TFH Cells in Promoting T Helper 17-Induced Neuroinflammation.
Frontiers in immunology
Quinn JL,Kumar G,Agasing A,Ko RM,Axtell RC
48-5902 was used in Flow cytometry/Cell sorting to study how T and B cells cooperate in the pathogenesis of multiple sclerosis.
Mon Apr 08 00:00:00 EDT 2019
Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.
Molecular medicine reports
Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
Nature communications
Barwick BG,Scharer CD,Martinez RJ,Price MJ,Wein AN,Haines RR,Bally APR,Kohlmeier JE,Boss JM
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Immunofluorescence
Tue May 15 00:00:00 EDT 2018
Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.
Nature communications
Zhang CJ,Wang C,Jiang M,Gu C,Xiao J,Chen X,Martin BN,Tang F,Yamamoto E,Xian Y,Wang H,Li F,Sartor RB,Smith H,Husni ME,Shi FD,Gao J,Carman J,Dongre A,McKarns SC,Coppieters K,Jørgensen TN,Leonard WJ,Li X
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Mon Jul 16 00:00:00 EDT 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates.
mBio
Schager AE,Dominguez-Medina CC,Necchi F,Micoli F,Goh YS,Goodall M,Flores-Langarica A,Bobat S,Cook CNL,Arcuri M,Marini A,King LDW,Morris FC,Anderson G,Toellner KM,Henderson IR,López-Macías C,MacLennan CA,Cunningham AF
48-5902 was used in Flow cytometry/Cell sorting to study how antibody responses to bacterial antigens develop and how vaccines like generalised modules for membrane antigens can work and help prevent infection.
Tue Mar 06 00:00:00 EST 2018
B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting.
Cell reports
Turner JS,Ke F,Grigorova IL
48-5902-82 was used in Flow cytometry/Cell sorting to investigate how T cells influence germinal center B cell expansion and plasmablast formation.
Tue Nov 06 00:00:00 EST 2018
Affinity Maturation Is Impaired by Natural Killer Cell Suppression of Germinal Centers.
Cell reports
Rydyznski CE,Cranert SA,Zhou JQ,Xu H,Kleinstein SH,Singh H,Waggoner SN
48-5902 was used in Flow cytometry/Cell sorting to elucidate the role of natural killer cells as robust negative regulators of somatic hypermutation in antigen-reactive B cells.
Tue Sep 25 00:00:00 EDT 2018
Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.
The Journal of experimental medicine
Girelli Zubani G,Zivojnovic M,De Smet A,Albagli-Curiel O,Huetz F,Weill JC,Reynaud CA,Storck S
48-5902 was used in Flow cytometry/Cell sorting to study how U:G mismatches is translated into the single-strand nick required for error prone synthesis.
Mon Apr 03 00:00:00 EDT 2017
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin.
Frontiers in immunology
Sun JB,Holmgren J,Larena M,Terrinoni M,Fang Y,Bresnick AR,Xiang Z
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Immunofluorescence
Wed Nov 20 00:00:00 EST 2019
Antigen Acquisition Enables Newly Arriving B Cells To Enter Ongoing Immunization-Induced Germinal Centers.
Journal of immunology (Baltimore, Md. : 1950)
Turner JS,Benet ZL,Grigorova IL
48-5902 was used in Flow cytometry/Cell sorting to show that naive B cells have a limited window of time during which they can undergo Ag-driven activation and join ongoing immunization-induced germinal center responses.
Tue Aug 15 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization.
Nature communications
Bemark M,Hazanov H,Strömberg A,Komban R,Holmqvist J,Köster S,Mattsson J,Sikora P,Mehr R,Lycke NY
48-5902 was used in Flow cytometry/Cell sorting to study the effects of oral immunisation on inducing gut mucosal memory in B cells.
Tue Sep 06 00:00:00 EDT 2016
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization.
Nature communications
Bemark M,Hazanov H,Strömberg A,Komban R,Holmqvist J,Köster S,Mattsson J,Sikora P,Mehr R,Lycke NY
48-5902 was used in Flow cytometry/Cell sorting to study the effects of oral immunisation on inducing gut mucosal memory in B cells.
Tue Sep 06 00:00:00 EDT 2016
BILL-cadherin/cadherin-17 contributes to the survival of memory B cells.
PloS one
Funakoshi S,Shimizu T,Numata O,Ato M,Melchers F,Ohnishi K
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Wed Sep 16 00:00:00 EDT 2015
PD-L1hi B cells are critical regulators of humoral immunity.
Nature communications
Khan AR,Hams E,Floudas A,Sparwasser T,Weaver CT,Fallon PG
48-5902 was used in Flow cytometry/Cell sorting to demonstrate that elevated PD-L1 expression on B cells is an important regulator of T follicular helper-cell activity, downstream antibody responses and autoimmune disease.
Thu Jan 22 00:00:00 EST 2015
Intravascular staining for discrimination of vascular and tissue leukocytes.
Nature protocols
Anderson KG,Mayer-Barber K,Sung H,Beura L,James BR,Taylor JJ,Qunaj L,Griffith TS,Vezys V,Barber DL,Masopust D
48-5902 was used in Flow cytometry/Cell sorting to outline a protocol for the validation and use of intravascular staining to define innate and adaptive immune cells in mice.
Wed Jan 01 00:00:00 EST 2014
Mutation of POLB causes lupus in mice.
Cell reports
Senejani AG,Liu Y,Kidane D,Maher SE,Zeiss CJ,Park HJ,Kashgarian M,McNiff JM,Zelterman D,Bothwell AL,Sweasy JB
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Flow Cytometry
Thu Jan 16 00:00:00 EST 2014
Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.
The EMBO journal
Panda S,Zhang J,Tan NS,Ho B,Ding JL
Published figure using GL7 monoclonal antibody (Product # 48-5902-82) in Immunofluorescence
Wed Nov 13 00:00:00 EST 2013
Human B-lymphocytes express alpha2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2.
The Journal of biological chemistry
Kimura N,Ohmori K,Miyazaki K,Izawa M,Matsuzaki Y,Yasuda Y,Takematsu H,Kozutsumi Y,Moriyama A,Kannagi R
Fri Nov 02 00:00:00 EDT 2007
