Product References
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Airway Administration of Bacterial Lysate OM-85 Protects Mice Against Respiratory Syncytial Virus Infection.
Frontiers in immunology
Antunes KH,Cassão G,Santos LD,Borges SG,Poppe J,Gonçalves JB,Nunes EDS,Recacho GF,Sousa VB,Da Silva GS,Mansur D,Stein RT,Pasquali C,De Souza APD
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue May 24 00:00:00 EDT 2022
Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1.
JCI insight
Klaus T,Wilson AS,Vicari E,Hadaschik E,Klein M,Helbich SSC,Kamenjarin N,Hodapp K,Schunke J,Haist M,Butsch F,Probst HC,Enk AH,Mahnke K,Waisman A,Bednarczyk M,Bros M,Bopp T,Grabbe S
50-9966-42 was used in Flow cytometry/Cell sorting to demonstrate a crucial role of LFA-1 on Treg to maintain immune homeostasis by modifying T cell-DC interactions and CD4+ T cell activation.
Thu Dec 22 00:00:00 EST 2022
The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma.
The Journal of experimental medicine
Verma M,Michalec L,Sripada A,McKay J,Sirohi K,Verma D,Sheth D,Martin R,Dyjack N,Seibold MA,Knapp JR,Tu TH,O'Connor BP,Gorska MM,Alam R
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
50-9966-42 was used in Flow cytometry/Cell sorting to demonstrate HDAC3 is essential during CD4+ T-cell activation to repress cholesterol efflux.
Thu Dec 02 00:00:00 EST 2021
Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma.
Cell reports. Medicine
Chao JL,Korzinkin M,Zhavoronkov A,Ozerov IV,Walker MT,Higgins K,Lingen MW,Izumchenko E,Savage PA
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue Sep 21 00:00:00 EDT 2021
LmjF.36.3850, a novel hypothetical Leishmania major protein, contributes to the infection.
Immunology
Zutshi S,Sarode AY,Ghosh SK,Jha MK,Sudan R,Kumar S,Sadhale LP,Roy S,Saha B
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
LmjF.36.3850, a novel hypothetical Leishmania major protein, contributes to the infection.
Immunology
Zutshi S,Sarode AY,Ghosh SK,Jha MK,Sudan R,Kumar S,Sadhale LP,Roy S,Saha B
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
A coordinated progression of progenitor cell states initiates urinary tract development.
Nature communications
Sanchez-Ferras O,Pacis A,Sotiropoulou M,Zhang Y,Wang YC,Bourgey M,Bourque G,Ragoussis J,Bouchard M
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Immunohistochemistry
Tue May 11 00:00:00 EDT 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity.
Immunity
Turner JA,Stephen-Victor E,Wang S,Rivas MN,Abdel-Gadir A,Harb H,Cui Y,Fanny M,Charbonnier LM,Fong JJH,Benamar M,Wang L,Burton OT,Bansal K,Bry L,Zhu C,Li QZ,Clement RL,Oettgen HC,Crestani E,Rachid R,Sage PT,Chatila TA
50-9966-42 was used in Flow Cytometry to show that Treg cells in food allergy (FA) had decreased expression of transforming growth factor beta 1 (TGF-β1) because of interleukin-4 (IL-4)- and signal transducer and activator of transciription-6 (STAT6)-dependent inhibition of Tgfb1 transcription.
Tue Dec 15 00:00:00 EST 2020
Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.
Cell host & microbe
Wiesner DL,Merkhofer RM,Ober C,Kujoth GC,Niu M,Keller NP,Gern JE,Brockman-Schneider RA,Evans MD,Jackson DJ,Warner T,Jarjour NN,Esnault SJ,Feldman MB,Freeman M,Mou H,Vyas JM,Klein BS
50-9966 was used in Flow cytometry/Cell sorting to conclude that club cells detect junction damage as mechanical stress, which signals danger via TRPV4, calcium, and calcineurin to initiate allergic sensitization.
Wed Apr 08 00:00:00 EDT 2020
Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance.
Mucosal immunology
Dobson HE,Dias LDS,Kohn EM,Fites S,Wiesner DL,Dileepan T,Kujoth GC,Abraham A,Ostroff GR,Klein BS,Wüthrich M
50-9966 was used in Flow cytometry/Cell sorting to report the identification of a novel fungal antigen that we harnessed for mucosal vaccination and tetramer generation to test whether we can elicit protective, antigen-specific tissue-resident memory (Trm) CD4+ T cells in the lung parenchyma.
Fri May 01 00:00:00 EDT 2020
Novel, Non-Gene-Destructive Knock-In Reporter Mice Refute the Concept of Monoallelic Gata3 Expression.
Journal of immunology (Baltimore, Md. : 1950)
Rao TN,Kumar S,Pulikkottil AJ,Oliveri F,Hendriks RW,Beckel F,Fehling HJ
50-9966 was used in Flow cytometry/Cell sorting to show that GATIR mice faithfully reflect endogenous Gata3 expression without disturbing the development of GATA-3-dependent lymphoid cell populations.
Fri May 01 00:00:00 EDT 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue Jan 14 00:00:00 EST 2020
Bendamustine with total body irradiation conditioning yields tolerant T-cells while preserving T-cell-dependent graft-versus-leukemia.
Oncoimmunology
Stokes J,Hoffman EA,Molina MS,Kummet N,Simpson RJ,Zeng Y,Katsanis E
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Wed Jul 14 00:00:00 EDT 2021
The obesity-induced adipokine sST2 exacerbates adipose Treg and ILC2 depletion and promotes insulin resistance.
Science advances
Zhao XY,Zhou L,Chen Z,Ji Y,Peng X,Qi L,Li S,Lin JD
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity.
Nature communications
Kimura S,Nakamura Y,Kobayashi N,Shiroguchi K,Kawakami E,Mutoh M,Takahashi-Iwanaga H,Yamada T,Hisamoto M,Nakamura M,Udagawa N,Sato S,Kaisho T,Iwanaga T,Hase K
50-9966 was used in Flow cytometry/Cell sorting to identify that the balance between infectious risk and the ability to perform immunosurveillance at the mucosal surface is dependent on osteprotegerin-dependent self-regulation of M cell differentiation.
Mon Jan 13 00:00:00 EST 2020
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
50-9966 was used in Flow cytometry/Cell sorting to shed light on the potential involvement of peripheral T and B cell immunity against this mycotic infection.
Mon May 31 00:00:00 EDT 2021
Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Nature
Esterházy D,Canesso MCC,Mesin L,Muller PA,de Castro TBR,Lockhart A,ElJalby M,Faria AMC,Mucida D
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation.
Science signaling
Jun JE,Kulhanek KR,Chen H,Chakraborty A,Roose JP
50-9966 was used in Flow cytometry/Cell sorting to investigate how both classical and alternative p38 pathways contribute to T cell activation and therefore the immune balance.
Tue Jul 23 00:00:00 EDT 2019
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.
Nature communications
Eissmann MF,Dijkstra C,Jarnicki A,Phesse T,Brunnberg J,Poh AR,Etemadi N,Tsantikos E,Thiem S,Huntington ND,Hibbs ML,Boussioutas A,Grimbaldeston MA,Buchert M,O'Donoghue RJJ,Masson F,Ernst M
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Fri Jun 21 00:00:00 EDT 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
50-9966 was used in Flow cytometry/Cell sorting to show that progranulin (PGRN) can reduce NK cell cytotoxicity through reduction of NK cell expansion, granzyme B transcription, and NK cell-mediated lysis of target cells.
Thu Sep 05 00:00:00 EDT 2019
Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine.
The Journal of experimental medicine
Li N,van Unen V,Höllt T,Thompson A,van Bergen J,Pezzotti N,Eisemann E,Vilanova A,Chuva de Sousa Lopes SM,Lelieveldt BPF,Koning F
Mon May 07 00:00:00 EDT 2018
Stability and function of regulatory T cells expressing the transcription factor T-bet.
Nature
Levine AG,Mendoza A,Hemmers S,Moltedo B,Niec RE,Schizas M,Hoyos BE,Putintseva EV,Chaudhry A,Dikiy S,Fujisawa S,Chudakov DM,Treuting PM,Rudensky AY
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2017
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
50-9966 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 EST 2017
The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development.
Immunity
Miyazaki M,Miyazaki K,Chen K,Jin Y,Turner J,Moore AJ,Saito R,Yoshida K,Ogawa S,Rodewald HR,Lin YC,Kawamoto H,Murre C
50-9966 was used in Flow cytometry/Cell sorting to propose that the E-Id protein axis specifies innate and adaptive lymphoid cell fate.
Tue May 16 00:00:00 EDT 2017
Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF-IRF4 transcription factor complex.
Nature immunology
Iwata A,Durai V,Tussiwand R,Briseño CG,Wu X,Grajales-Reyes GE,Egawa T,Murphy TL,Murphy KM
50-9966 was used in Flow cytometry/Cell sorting to study the mechanism by which the abundance of IRF4 induces distinct types of responses.
Mon May 01 00:00:00 EDT 2017
Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy.
Cell stem cell
Lechner AJ,Driver IH,Lee J,Conroy CM,Nagle A,Locksley RM,Rock JR
50-9966 was used in Flow cytometry/Cell sorting to provide evidence that group 2 innate lymphoid cells are a source of IL-13, which promotes lung regeneration.
Thu Jul 06 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
50-9966 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis.
The Journal of allergy and clinical immunology
Chen PC,Hsieh MH,Kuo WS,Kao HF,Hsu CL,Wang JY
50-9966 was used in Flow cytometry/Cell sorting to evaluate the effect of extensive water-soluble chitosan in allergic rhinitis.
Sun Oct 01 00:00:00 EDT 2017
Eosinophils are required to suppress Th2 responses in Peyer's patches during intestinal infection by nematodes.
Mucosal immunology
Strandmark J,Steinfelder S,Berek C,Kühl AA,Rausch S,Hartmann S
50-9966 was used in Flow cytometry/Cell sorting to study whether eosinophils affect the local T-cell and antibody response in the gut-associated lymphoid tissue during enteric infections.
Mon May 01 00:00:00 EDT 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
Wed Feb 01 00:00:00 EST 2017
Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.
Wellcome open research
Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Sat Jan 09 00:00:00 EST 2021
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4.
Nature communications
Campos Carrascosa L,Klein M,Kitagawa Y,Lückel C,Marini F,König A,Guralnik A,Raifer H,Hagner-Benes S,Rädler D,Böck A,Kang C,Lohoff M,Garn H,Schaub B,Berberich-Siebelt F,Sakaguchi S,Bopp T,Huber M
50-9966 was used in Flow cytometry/Cell sorting to study the opposing effects of interferon regulatory factor1 and IRF4 on T helper 9 cell differentiation.
Fri May 12 00:00:00 EDT 2017
Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response.
Frontiers in cellular and infection microbiology
Ahmed N,French T,Rausch S,Kühl A,Hemminger K,Dunay IR,Steinfelder S,Hartmann S
50-9966 was used in Flow cytometry/Cell sorting to conclude a previous T. gondii infection limits a helminth-specific Th2 immune response while promoting a shift toward a Th1-type immune response.
Mon Apr 02 00:00:00 EDT 2018
Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses.
Nature immunology
Halim TY,Hwang YY,Scanlon ST,Zaghouani H,Garbi N,Fallon PG,McKenzie AN
50-9966 was used in Flow cytometry/Cell sorting to investigate the role of ILC2 cells in allergic inflammation, showing that they license dendritic cells to potentiate memory TH2 cell responses.
Fri Jan 01 00:00:00 EST 2016
A Role for Regulatory T Cells in a Murine Model of Epicutaneous Toluene Diisocyanate Sensitization.
Toxicological sciences : an official journal of the Society of Toxicology
Long CM,Marshall NB,Lukomska E,Kashon ML,Meade BJ,Shane H,Anderson SE
50-9966 was used in Flow cytometry/Cell sorting to delineate the immunologic mechanisms of chemical-induced allergic disease.
Fri Jul 01 00:00:00 EDT 2016
Susceptibility to Ticks and Lyme Disease Spirochetes Is Not Affected in Mice Coinfected with Nematodes.
Infection and immunity
Maaz D,Rausch S,Richter D,Krücken J,Kühl AA,Demeler J,Blümke J,Matuschka FR,von Samson-Himmelstjerna G,Hartmann S
50-9966 was used in Flow cytometry/Cell sorting to analyse the immunological impact of the nematode/tick coinfection, showing that susceptibility to ticks and Lyme disease is not affected by coinfection.
Sun May 01 00:00:00 EDT 2016
The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome.
European journal of immunology
Goyvaerts C,Broos K,Escors D,Heirman C,Raes G,De Baetselier P,Thielemans K,Breckpot K
50-9966-42 was used in Flow Cytometry to demonstrate that codelivery of IL-12 enhances the CD4(+) TH 1 profile irrespective of its delivery mode, while an increase in cytotoxic and therapeutic CD8(+) T cells was only induced upon VSV-G-LV injection.
Tue Dec 01 00:00:00 EST 2015
Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Marquardt N,Béziat V,Nyström S,Hengst J,Ivarsson MA,Kekäläinen E,Johansson H,Mjösberg J,Westgren M,Lankisch TO,Wedemeyer H,Ellis EC,Ljunggren HG,Michaëlsson J,Björkström NK
50-9966 was used in Flow cytometry/Cell sorting to study the unique lineage of CD49a(+)DX5(-) NK cells, showing that they are readily detectable in the liver but not in hepatic venous or peripheral blood.
Sun Mar 15 00:00:00 EDT 2015
Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
PloS one
Deng YQ,Yang YQ,Wang SB,Li F,Liu MZ,Hua QQ,Tao ZZ
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue May 31 00:00:00 EDT 2016
Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice.
Journal of virology
Boyoglu-Barnum S,Chirkova T,Todd SO,Barnum TR,Gaston KA,Jorquera P,Haynes LM,Tripp RA,Moore ML,Anderson LJ
50-9966 was used in Flow cytometry/Cell sorting to suggest that the RSV G protein not only contributes to disease, but also dampens the host immune response to infection.
Mon Sep 01 00:00:00 EDT 2014
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
50-9966 was used in Flow cytometry/Cell sorting to study how the GATA3-miR-29b axis regulates the tumour microenvironment, and inhibits metastasis to open up possibilities for therapeutic intervention in breast cancer.
Fri Feb 01 00:00:00 EST 2013
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
50-9966 was used in Flow cytometry/Cell sorting to study how the GATA3-miR-29b axis regulates the tumour microenvironment, and inhibits metastasis to open up possibilities for therapeutic intervention in breast cancer.
Fri Feb 01 00:00:00 EST 2013
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Nature cell biology
Chou J,Lin JH,Brenot A,Kim JW,Provot S,Werb Z
50-9966 was used in Flow cytometry/Cell sorting to study how the GATA3-miR-29b axis regulates the tumour microenvironment, and inhibits metastasis to open up possibilities for therapeutic intervention in breast cancer.
Fri Feb 01 00:00:00 EST 2013
Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome.
The Journal of investigative dermatology
Gibson HM,Mishra A,Chan DV,Hake TS,Porcu P,Wong HK
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Regulatory T cells prevent Th2 immune responses and pulmonary eosinophilia during respiratory syncytial virus infection in mice.
Journal of virology
Durant LR,Makris S,Voorburg CM,Loebbermann J,Johansson C,Openshaw PJ
50-9966 was used in Flow cytometry/Cell sorting to provide evidence that dysregulation of normal immune responses to viral infection may contribute to severe respiratory viral disease.
Tue Oct 01 00:00:00 EDT 2013
Mesenchymal stem cells alleviate TNBS-induced colitis by modulating inflammatory and autoimmune responses.
World journal of gastroenterology
Chen QQ,Yan L,Wang CZ,Wang WH,Shi H,Su BB,Zeng QH,Du HT,Wan J
Published figure using Gata-3 monoclonal antibody (Product # 50-9966-42) in Western Blot
Wed Aug 07 00:00:00 EDT 2013
Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.
PloS one
Serre K,Bénézech C,Desanti G,Bobat S,Toellner KM,Bird R,Chan S,Kastner P,Cunningham AF,Maclennan IC,Mohr E
50-9966 was used in Flow cytometry/Cell sorting to reveal the selective upregulation of Helios during Th2 and TFh responses to alum-protein vaccines.
Mon Oct 17 00:00:00 EDT 2011
Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to sheep RBC and chicken ovalbumin.
Journal of immunology (Baltimore, Md. : 1950)
Guan H,Nagarkatti PS,Nagarkatti M
Wed Jul 01 00:00:00 EDT 2009