Product References
P4HA1 activates HMGCS1 to promote nasopharyngeal carcinoma ferroptosis resistance and progression.
Cellular signalling
Zhou R,Qiu L,Zhou L,Geng R,Yang S,Wu J
Mon May 01 00:00:00 EDT 2023
ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
International journal of molecular sciences
Tang S,Ma J,Su P,Lei H,Tong Y,Cai L,Xu S,Mao X,Sun P
Thu Feb 16 00:00:00 EST 2023
ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
International journal of molecular sciences
Tang S,Ma J,Su P,Lei H,Tong Y,Cai L,Xu S,Mao X,Sun P
Thu Feb 16 00:00:00 EST 2023
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer.
Cell death & disease
Zheng YK,Zhou ZS,Wang GZ,Tu JY,Cheng HB,Ma SZ,Ke C,Wang Y,Jian QP,Shu YH,Wu XW
Sat Apr 01 00:00:00 EDT 2023
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer.
Cell death & disease
Zheng YK,Zhou ZS,Wang GZ,Tu JY,Cheng HB,Ma SZ,Ke C,Wang Y,Jian QP,Shu YH,Wu XW
Sat Apr 01 00:00:00 EDT 2023
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.
Cancer cell
Zhou W,Liu H,Yuan Z,Zundell J,Towers M,Lin J,Lombardi S,Nie H,Murphy B,Yang T,Wang C,Liao L,Goldman AR,Kannan T,Kossenkov AV,Drapkin R,Montaner LJ,Claiborne DT,Zhang N,Wu S,Zhang R
Mon Apr 10 00:00:00 EDT 2023
Upregulation of Superenhancer-Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Peng JY,Cai DK,Zeng RL,Zhang CY,Li GC,Chen SF,Yuan XQ,Peng L
Fri Oct 28 00:00:00 EDT 2022
Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao B,Jiang B,Xing W,Xie Z,Luo Z,Zou W
Sun May 01 00:00:00 EDT 2022
Itraconazole Inhibits the Growth of Cutaneous Squamous Cell Carcinoma by Targeting HMGCS1/ACSL4 Axis.
Frontiers in pharmacology
Xu C,Zhuo Y,Liu Y,Chen H
Sat Mar 05 00:00:00 EST 2022
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Frontiers in pharmacology
Li MT,Liu LL,Zhou Q,Huang LX,Shi YX,Hou JB,Lu HT,Yu B,Chen W,Guo ZY
Mon Jun 26 00:00:00 EDT 2023
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Frontiers in pharmacology
Li MT,Liu LL,Zhou Q,Huang LX,Shi YX,Hou JB,Lu HT,Yu B,Chen W,Guo ZY
Mon Jun 26 00:00:00 EDT 2023
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Frontiers in pharmacology
Li MT,Liu LL,Zhou Q,Huang LX,Shi YX,Hou JB,Lu HT,Yu B,Chen W,Guo ZY
Mon Jun 26 00:00:00 EDT 2023
Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid.
Frontiers in pharmacology
Li MT,Liu LL,Zhou Q,Huang LX,Shi YX,Hou JB,Lu HT,Yu B,Chen W,Guo ZY
Mon Jun 26 00:00:00 EDT 2023
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Journal of clinical and translational hepatology
Chen CC,Xie XM,Zhao XK,Zuo S,Li HY
Wed Dec 28 00:00:00 EST 2022
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
The Journal of cell biology
Ho WY,Chang JC,Lim K,Cazenave-Gassiot A,Nguyen AT,Foo JC,Muralidharan S,Viera-Ortiz A,Ong SJM,Hor JH,Agrawal I,Hoon S,Arogundade OA,Rodriguez MJ,Lim SM,Kim SH,Ravits J,Ng SY,Wenk MR,Lee EB,Tucker-Kellogg G,Ling SC
Mon Sep 06 00:00:00 EDT 2021
miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway.
International journal of biological sciences
Zhao F,Ma S,Zhou Y,Wei B,Hao Z,Cui X,Xing L,Liu G,Jin L,Ma T,Shi L
Mon Dec 20 00:00:00 EST 2021
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Neuron
Li X,Zhang J,Li D,He C,He K,Xue T,Wan L,Zhang C,Liu Q
Wed Mar 17 00:00:00 EDT 2021
Transcriptomic Analysis Reveals the Protective Effects of Empagliflozin on Lipid Metabolism in Nonalcoholic Fatty Liver Disease.
Frontiers in pharmacology
Ma Y,Kan C,Qiu H,Liu Y,Hou N,Han F,Shi J,Sun X
Sat Jan 08 00:00:00 EST 2022
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Oxidative medicine and cellular longevity
Wang W,Hu X,Xia Z,Liu Z,Zhong Z,Lu Z,Liu A,Ye S,Cao Q,Wang Y,Zhu F,Ye Q
Wed Dec 16 00:00:00 EST 2020
Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Frontiers in cellular neuroscience
Shen Y,Ding M,Xie Z,Liu X,Yang H,Jin S,Xu S,Zhu Z,Wang Y,Wang D,Xu L,Zhou X,Wang P,Bi J
Wed Sep 30 00:00:00 EDT 2020
Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity.
Cell death & disease
Wang H,Lin C,Yao J,Shi H,Zhang C,Wei Q,Lu Y,Chen Z,Xing G,Cao X
Mon Aug 19 00:00:00 EDT 2019
OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway.
Experimental cell research
Zhang C,Zhang H,Zhang M,Lin C,Wang H,Yao J,Wei Q,Lu Y,Chen Z,Xing G,Cao X
Tue Oct 15 00:00:00 EDT 2019
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Neuroscience
Raihan O,Brishti A,Molla MR,Li W,Zhang Q,Xu P,Khan MI,Zhang J,Liu Q
Mon Oct 15 00:00:00 EDT 2018
The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
Neuroscience
Raihan O,Brishti A,Molla MR,Li W,Zhang Q,Xu P,Khan MI,Zhang J,Liu Q
Mon Oct 15 00:00:00 EDT 2018
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis.
The Journal of biological chemistry
Fryer LG,Jones B,Duncan EJ,Hutchison CE,Ozkan T,Williams PA,Alder O,Nieuwdorp M,Townley AK,Mensenkamp AR,Stephens DJ,Dallinga-Thie GM,Shoulders CC
Fri Feb 14 00:00:00 EST 2014
The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis.
The Journal of biological chemistry
Fryer LG,Jones B,Duncan EJ,Hutchison CE,Ozkan T,Williams PA,Alder O,Nieuwdorp M,Townley AK,Mensenkamp AR,Stephens DJ,Dallinga-Thie GM,Shoulders CC
Fri Feb 14 00:00:00 EST 2014
Identification of proteins that mediate the pro-viral functions of the interferon stimulated gene 15 in hepatitis C virus replication.
Antiviral research
Real CI,Megger DA,Sitek B,Jahn-Hofmann K,Ickenstein LM,John MJ,Walker A,Timm J,Kuhlmann K,Eisenacher M,Meyer HE,Gerken G,Broering R,Schlaak JF
Sun Dec 01 00:00:00 EST 2013
Identification of proteins that mediate the pro-viral functions of the interferon stimulated gene 15 in hepatitis C virus replication.
Antiviral research
Real CI,Megger DA,Sitek B,Jahn-Hofmann K,Ickenstein LM,John MJ,Walker A,Timm J,Kuhlmann K,Eisenacher M,Meyer HE,Gerken G,Broering R,Schlaak JF
Sun Dec 01 00:00:00 EST 2013
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression.
Molecular & cellular proteomics : MCP
Saraon P,Cretu D,Musrap N,Karagiannis GS,Batruch I,Drabovich AP,van der Kwast T,Mizokami A,Morrissey C,Jarvi K,Diamandis EP
Sat Jun 01 00:00:00 EDT 2013
Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression.
Molecular & cellular proteomics : MCP
Saraon P,Cretu D,Musrap N,Karagiannis GS,Batruch I,Drabovich AP,van der Kwast T,Mizokami A,Morrissey C,Jarvi K,Diamandis EP
Sat Jun 01 00:00:00 EDT 2013
