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This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) isoform 1; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) isoform 2; B130032C06Rik; HMG-CoA synthase; HMGCS; Hmgcs1; HMGCS1 protein-like; hydroxymethylglutaryl-CoA synthase 1; hydroxymethylglutaryl-CoA synthase, cytoplasmic; Unknown (protein for IMAGE:7955111)
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