Product References
Microbially-Induced Exosomes from Dendritic Cells Promote Paracrine Immune Senescence: Novel Mechanism of Bone Degenerative Disease in Mice.
Aging and disease
Elsayed R,Elashiry M,Liu Y,Morandini AC,El-Awady A,Elashiry MM,Hamrick M,Cutler CW
12-7114-82 was used in Flow cytometry/Cell sorting to conclude that immune senescence, compounded by advanced age, and accelerated by oral dysbiosis and its induced SASP exosomes, plays a pivotal role in the pathophysiology of experimental periodontitis.
Wed Feb 01 00:00:00 EST 2023
Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis.
Brain, behavior, and immunity
Zou L,He J,Gu L,Shahror RA,Li Y,Cao T,Wang S,Zhu J,Huang H,Chen F,Fan X,Wu J,Chao W
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Tue Feb 01 00:00:00 EST 2022
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Oxidative medicine and cellular longevity
Luo Y,Guo J,Jia W,Wu M,Yin F,Niu G,Shih DQ,Targan SR,Zhang X
12-7114-82 was used in Flow cytometry/Cell sorting to investigate the role of TNF-like ligand 1 aberrance (TL1A) in nonalcoholic steatohepatitis (NASH).
Fri Mar 04 00:00:00 EST 2022
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization.
Oxidative medicine and cellular longevity
Luo Y,Guo J,Jia W,Wu M,Yin F,Niu G,Shih DQ,Targan SR,Zhang X
12-7114-82 was used in Flow cytometry/Cell sorting to investigate the role of TNF-like ligand 1 aberrance (TL1A) in nonalcoholic steatohepatitis (NASH).
Fri Mar 04 00:00:00 EST 2022
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway.
Journal of neuroinflammation
Duan RN,Yang CL,Du T,Liu A,Wang AR,Sun WJ,Li X,Li JX,Yan CZ,Liu QJ
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Mon Jun 28 00:00:00 EDT 2021
NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis.
Frontiers in immunology
Guo X,Xu X,Li T,Yu Q,Wang J,Chen Y,Ding S,Zhu L,Zou G,Zhang X
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Tue Jan 18 00:00:00 EST 2022
MicroRNA-326 attenuates immune escape and prevents metastasis in lung adenocarcinoma by targeting PD-L1 and B7-H3.
Cell death discovery
Shao L,He Q,Wang J,He F,Lin S,Wu L,Gao Y,Ma W,Dong J,Yang X,Li F
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Tue Jun 15 00:00:00 EDT 2021
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation.
Nature communications
Jones N,Blagih J,Zani F,Rees A,Hill DG,Jenkins BJ,Bull CJ,Moreira D,Bantan AIM,Cronin JG,Avancini D,Jones GW,Finlay DK,Vousden KH,Vincent EE,Thornton CA
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Interleukin-1β Suppresses Gastrin via Primary Cilia and Induces Antral Hyperplasia.
Cellular and molecular gastroenterology and hepatology
Ding L,Sontz EA,Saqui-Salces M,Merchant JL
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2022
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis.
Cell
Kitamoto S,Nagao-Kitamoto H,Jiao Y,Gillilland MG,Hayashi A,Imai J,Sugihara K,Miyoshi M,Brazil JC,Kuffa P,Hill BD,Rizvi SM,Wen F,Bishu S,Inohara N,Eaton KA,Nusrat A,Lei YL,Giannobile WV,Kamada N
12-7114-82 was used in Flow Cytometry to conclude that oral inflammation, such as periodontitis, exacerbates gut inflammation by supplying the gut with both colitogenic pathobionts and pathogenic T cells.
Thu Jul 23 00:00:00 EDT 2020
Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation.
Nature immunology
Di Gioia M,Spreafico R,Springstead JR,Mendelson MM,Joehanes R,Levy D,Zanoni I
12-7114 was used in Flow Cytometry to report that the self-encoded oxidized phospholipid oxPAPC alters the metabolism of macrophages exposed to lipopolysaccharide.
Wed Jan 01 00:00:00 EST 2020
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments.
Journal of neuroinflammation
Reverchon F,de Concini V,Larrigaldie V,Benmerzoug S,Briault S,Togbé D,Ryffel B,Quesniaux VFJ,Menuet A
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Fri Sep 11 00:00:00 EDT 2020
Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments.
Journal of neuroinflammation
Reverchon F,de Concini V,Larrigaldie V,Benmerzoug S,Briault S,Togbé D,Ryffel B,Quesniaux VFJ,Menuet A
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Fri Sep 11 00:00:00 EDT 2020
Triacylglycerol synthesis enhances macrophage inflammatory function.
Nature communications
Castoldi A,Monteiro LB,van Teijlingen Bakker N,Sanin DE,Rana N,Corrado M,Cameron AM,Hässler F,Matsushita M,Caputa G,Klein Geltink RI,Büscher J,Edwards-Hicks J,Pearce EL,Pearce EJ
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Fri Aug 14 00:00:00 EDT 2020
Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment.
The Journal of experimental medicine
Lee SH,Charmoy M,Romano A,Paun A,Chaves MM,Cope FO,Ralph DA,Sacks DL
12-7114 was used in Flow cytometry/Cell sorting to study the origin and functional specialisation of dermal macrophages in cutaneous infections.
Tue Jan 02 00:00:00 EST 2018
1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
JCI insight
Wasnik S,Rundle CH,Baylink DJ,Yazdi MS,Carreon EE,Xu Y,Qin X,Lau KW,Tang X
12-7114 was used in Flow cytometry/Cell sorting to define the role of M1 macrophages at bone injury sites via the function of 1,25-Dihydroxyvitamin D in suppressing M1 but promoting M2 differentiation.
Thu Sep 06 00:00:00 EDT 2018
Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain.
Immunity
Varol D,Mildner A,Blank T,Shemer A,Barashi N,Yona S,David E,Boura-Halfon S,Segal-Hayoun Y,Chappell-Maor L,Keren-Shaul H,Leshkowitz D,Hornstein E,Fuhrmann M,Amit I,Maggio N,Prinz M,Jung S
12-7114 was used in Flow cytometry/Cell sorting to examine the impact of post-transcriptional control mediated by microRNAs on microglial performance during development and adulthood.
Tue Jun 20 00:00:00 EDT 2017
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.
Cell metabolism
Westerterp M,Gautier EL,Ganda A,Molusky MM,Wang W,Fotakis P,Wang N,Randolph GJ,D'Agati VD,Yvan-Charvet L,Tall AR
12-7114 was used in Flow cytometry/Cell sorting to identify an essential role of DC cholesterol efflux pathways in maintaining immune tolerance.
Tue Jun 06 00:00:00 EDT 2017
Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing.
Frontiers in immunology
Kimball AS,Joshi AD,Boniakowski AE,Schaller M,Chung J,Allen R,Bermick J,Carson WF,Henke PK,Maillard I,Kunkel SL,Gallagher KA
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation.
Nature
Ravindran R,Loebbermann J,Nakaya HI,Khan N,Ma H,Gama L,Machiah DK,Lawson B,Hakimpour P,Wang YC,Li S,Sharma P,Kaufman RJ,Martinez J,Pulendran B
12-7114 was used in Flow cytometry/Cell sorting to reveal a mechanism that couples amino acid sensing with control of intestinal inflammation via GCN2.
Thu Mar 24 00:00:00 EDT 2016
Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells.
Cancer cell
Blaisdell A,Crequer A,Columbus D,Daikoku T,Mittal K,Dey SK,Erlebacher A
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.
Immunity & ageing : I & A
Elahy M,Jackaman C,Mamo JC,Lam V,Dhaliwal SS,Giles C,Nelson D,Takechi R
Wed Mar 18 00:00:00 EDT 2015
Differential ASC requirements reveal a key role for neutrophils and a noncanonical IL-1β response to Pseudomonas aeruginosa.
American journal of physiology. Lung cellular and molecular physiology
Patankar YR,Mabaera R,Berwin B
12-7114 was used in Flow cytometry/Cell sorting to demonstrate the physiological contribution of neutrophils as a source of IL-1β in response to P. aeruginosa infection.
Thu Oct 15 00:00:00 EDT 2015
Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Nature medicine
Kim HY,Lee HJ,Chang YJ,Pichavant M,Shore SA,Fitzgerald KA,Iwakura Y,Israel E,Bolger K,Faul J,DeKruyff RH,Umetsu DT
12-7114 was used in Flow cytometry/Cell sorting to show that IL-17 producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Wed Jan 01 00:00:00 EST 2014
The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines.
PLoS pathogens
Asrat S,Dugan AS,Isberg RR
12-7114 was used in Flow cytometry/Cell sorting to show how the protein translation inhibition induced by L. pneumophila is bypassed by MyD88, allowing pro-inflammatory cytokine translation.
Tue Jul 01 00:00:00 EDT 2014
Acidosis potentiates the host proinflammatory interleukin-1β response to Pseudomonas aeruginosa infection.
Infection and immunity
Torres IM,Patankar YR,Shabaneh TB,Dolben E,Hogan DA,Leib DA,Berwin BL
12-7114 was used in Flow cytometry/Cell sorting to show that extracellular pH governs the host inflammatory response against P. aeruginosa via synergistic mechanisms that modulate cytokine release.
Sat Nov 01 00:00:00 EDT 2014
Cell-selective inhibition of NF-κB signaling improves therapeutic index in a melanoma chemotherapy model.
Cancer discovery
Enzler T,Sano Y,Choo MK,Cottam HB,Karin M,Tsao H,Park JM
Published figure using IL-1 beta (Pro-form) monoclonal antibody (Product # 12-7114-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011