Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
EMBO reports
Zhu K,Wang Y,Sarlus H,Geng K,Nutma E,Sun J,Kung SY,Bay C,Han J,Min JH,Benito-Cuesta I,Lund H,Amor S,Wang J,Zhang XM,Kutter C,Guerreiro-Cacais AO,Högberg B,Harris RA
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Tue Jul 05 00:00:00 EDT 2022
RORγt phosphorylation protects against T cell-mediated inflammation.
Cell reports
Ma S,Patel SA,Abe Y,Chen N,Patel PR,Cho BS,Abbasi N,Zeng S,Schnabl B,Chang JT,Huang WJM
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Tue Mar 15 00:00:00 EDT 2022
Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes.
The Journal of experimental medicine
Lin CH,Chen MC,Lin LL,Christian DA,Min B,Hunter CA,Lu LF
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Fri Jan 28 00:00:00 EST 2022
Characterisation of Macrophage Polarisation in Mice Infected with Ninoa Strain of Trypanosoma cruzi.
Pathogens (Basel, Switzerland)
Medina-Buelvas DM,Rodríguez-Sosa M,Vega L
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Sat Nov 06 00:00:00 EDT 2021
Local Sustained GM-CSF Delivery by Genetically Engineered Encapsulated Cells Enhanced Both Cellular and Humoral SARS-CoV-2 Spike-Specific Immune Response in an Experimental Murine Spike DNA Vaccination Model.
Vaccines
Vernet R,Charrier E,Cosset E,Fièvre S,Tomasello U,Grogg J,Mach N
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.
Cell research
Wang S,Qu Y,Xia P,Chen Y,Zhu X,Zhang J,Wang G,Tian Y,Ying J,Fan Z
14-7101-81 was used in Flow Cytometry to profile tumor infiltrating innate lymphoid cells in colorectal cancer at early and late stages.
Wed Jul 01 00:00:00 EDT 2020
Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production.
Journal of leukocyte biology
Siwapornchai N,Lee JN,Tchalla EYI,Bhalla M,Yeoh JH,Roggensack SE,Leong JM,Bou Ghanem EN
14-7101-81 was used in Flow Cytometry to explore why the antimicrobial efficacy of polymorphonuclear leukocytes declines over the course of infection.
Tue Sep 01 00:00:00 EDT 2020
Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation.
Brain sciences
Thome R,Boehm A,Ishikawa LLW,Casella G,Munhoz J,Ciric B,Zhang GX,Rostami A
14-7101-81 was used in Flow Cytometry to analyse the CNS of experimental autoimmune encephalomyelitis mice to identify and characterize the cells that are affected by chloroquine.
Fri Jun 05 00:00:00 EDT 2020
IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A+Foxp3+ Cells During Mucosal Infection and Is Dysregulated With Aging.
Frontiers in immunology
Bhaskaran N,Faddoul F,Paes da Silva A,Jayaraman S,Schneider E,Mamileti P,Weinberg A,Pandiyan P
14-7101-81 was used in Flow Cytometry to identify IL-1β/MyD88/Treg axis as a new component that modulates inflammatory responses in oral mucosa.
Mon Jun 28 00:00:00 EDT 2021
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.
Cell reports
Garg G,Muschaweckh A,Moreno H,Vasanthakumar A,Floess S,Lepennetier G,Oellinger R,Zhan Y,Regen T,Hiltensperger M,Peter C,Aly L,Knier B,Palam LR,Kapur R,Kaplan MH,Waisman A,Rad R,Schotta G,Huehn J,Kallies A,Korn T
14-7101-81 was used in Flow Cytometry to identify a Blimp1-dependent pathway that preserves Treg cell stability in inflamed non-lymphoid tissues.
Tue Feb 12 00:00:00 EST 2019
Neuronal impairment following chronic Toxoplasma gondii infection is aggravated by intestinal nematode challenge in an IFN-γ-dependent manner.
Journal of neuroinflammation
French T,Düsedau HP,Steffen J,Biswas A,Ahmed N,Hartmann S,Schüler T,Schott BH,Dunay IR
14-7101-81 was used in Flow cytometry/Cell sorting to investigate how neuroinflammation and the associated neural impairment can be modulated by peripheral inflammatory processes.
Mon Jul 29 00:00:00 EDT 2019
Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis.
Cellular & molecular immunology
Lu Y,Liu H,Bi Y,Yang H,Li Y,Wang J,Zhang Z,Wang Y,Li C,Jia A,Han L,Hu Y,Zhao Y,Wang R,Liu G
14-7101-81 was used in Flow Cytometry to reveal the dysregulation of glucocorticoid receptor expression in myeloid-derived suppressor cells during innate immunological hepatic injury and found that GR regulates the function of MDSCs through modulating HIF1α-dependent glycolysis.
Fri Jun 01 00:00:00 EDT 2018
Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis.
Journal of translational medicine
Yuan Y,Lin D,Feng L,Huang M,Yan H,Li Y,Chen Y,Lin B,Ma Y,Ye Z,Mei Y,Yu X,Zhou K,Zhang Q,Chen T,Zeng J
14-7101-81 was used in Flow Cytometry to show exposure to cigarette smoke upregulates miR-196b-5p in monocyte/macrophages from patients with long-term cigarette smoking-related pulmonary tuberculosis.
Tue Oct 16 00:00:00 EDT 2018
Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties.
Scientific reports
Leroux LP,Nasr M,Valanparambil R,Tam M,Rosa BA,Siciliani E,Hill DE,Zarlenga DS,Jaramillo M,Weinstock JV,Geary TG,Stevenson MM,Urban JF,Mitreva M,Jardim A
14-7101 was used in an ELISA assay to analyse the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties.
Mon Oct 29 00:00:00 EDT 2018
Inflammation-induced Id2 promotes plasticity in regulatory T cells.
Nature communications
Hwang SM,Sharma G,Verma R,Byun S,Rudra D,Im SH
14-7101 was used in Flow cytometry/Cell sorting to show that pro-inflammatory cytokines enhance the expression of transcription regulator Id2, which mediates cellular plasticity of Treg into ex-Foxp3 TH17 cells.
Fri Nov 09 00:00:00 EST 2018
The excretory-secretory products of Echinococcus granulosus protoscoleces stimulated IL-10 production in B cells via TLR-2 signaling.
BMC immunology
Pan W,Xu HW,Hao WT,Sun FF,Qin YF,Hao SS,Liu H,Cao JP,Shen YJ,Zheng KY
14-7101 was used in Flow cytometry/Cell sorting to investigate the effects of EgPSC-ESPs on the differentiation of IL-10-producing B cells.
Wed Oct 24 00:00:00 EDT 2018
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance.
The Journal of clinical investigation
Cruz LO,Hashemifar SS,Wu CJ,Cho S,Nguyen DT,Lin LL,Khan AA,Lu LF
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB.
EMBO molecular medicine
Huang SC,Wei PC,Hwang-Verslues WW,Kuo WH,Jeng YM,Hu CM,Shew JY,Huang CS,Chang KJ,Lee EY,Lee WH
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Neutralization
Fri Dec 01 00:00:00 EST 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-7101-81 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 EDT 2017
Inhibition of Inflammatory Gene Transcription by IL-10 Is Associated with Rapid Suppression of Lipopolysaccharide-Induced Enhancer Activation.
Journal of immunology (Baltimore, Md. : 1950)
Conaway EA,de Oliveira DC,McInnis CM,Snapper SB,Horwitz BH
14-7101 was used in an ELISA assay to demonstrate that inhibition of transcription is the primary mechanism for IL-10-mediated suppression in LPS-stimulated macrophages and that inhibited genes can be divided into two clusters.
Sat Apr 01 00:00:00 EDT 2017
Macrophage regulation of B cell proliferation.
Cellular immunology
Goldman N,Valiuskyte K,Londregan J,Swider A,Somerville J,Riggs JE
14-7101 was used in Flow cytometry/Cell sorting to assess the ability of peritoneal cavity B cells to respond to surrogate activating signals in the presence of high numbers of macrophages.
Sat Apr 01 00:00:00 EDT 2017
IFNGR1 signaling is associated with adverse pregnancy outcomes during infection with malaria parasites.
PloS one
Niikura M,Inoue SI,Mineo S,Asahi H,Kobayashi F
Wed Nov 29 00:00:00 EST 2017
Characterization of c-Maf+Foxp3- Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells.
Scientific reports
Chien CH,Yu HC,Chen SY,Chiang BL
14710181 was used in flow cytometry to generate and characterize Treg-of-B cells
Wed Apr 12 00:00:00 EDT 2017
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines.
PloS one
Singh S,Vedi S,Samrat SK,Li W,Kumar R,Agrawal B
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Tue Jul 19 00:00:00 EDT 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Wed May 25 00:00:00 EDT 2016
Lymphocytic Microparticles Modulate Angiogenic Properties of Macrophages in Laser-induced Choroidal Neovascularization.
Scientific reports
Tahiri H,Omri S,Yang C,Duhamel F,Samarani S,Ahmad A,Vezina M,Bussières M,Vaucher E,Sapieha P,Hickson G,Hammamji K,Lapointe R,Rodier F,Tremblay S,Royal I,Cailhier JF,Chemtob S,Hardy P
14710181 was used in flow cytometry to study the ability of lymphocyte-derived microparticles to modulate the gene expression pattern of angiogenesis-related factors in macrophages
Tue Nov 22 00:00:00 EST 2016
Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.
Nature communications
Ulland TK,Jain N,Hornick EE,Elliott EI,Clay GM,Sadler JJ,Mills KA,Janowski AM,Volk AP,Wang K,Legge KL,Gakhar L,Bourdi M,Ferguson PJ,Wilson ME,Cassel SL,Sutterwala FS
14-7101 was used in an ELISA assay to demonstrate that C57BL/6J mice have a functional defect in NLRP12, which is required by macrophages for effective neutrophil recruitment to inflammatory sites.
Tue Oct 25 00:00:00 EDT 2016
Towards programming immune tolerance through geometric manipulation of phosphatidylserine.
Biomaterials
Roberts RA,Eitas TK,Byrne JD,Johnson BM,Short PJ,McKinnon KP,Reisdorf S,Luft JC,DeSimone JM,Ting JP
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.
Cancer research
Kratochvill F,Gratz N,Qualls JE,Van De Velde LA,Chi H,Kovarik P,Murray PJ
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells.
Cancer research
Hong Y,Manoharan I,Suryawanshi A,Majumdar T,Angus-Hill ML,Koni PA,Manicassamy B,Mellor AL,Munn DH,Manicassamy S
14-7101 was used in Flow cytometry/Cell sorting to show that dendritic cells in the tumour microenvironment acquire the ability to metabolise vitamin A to produce retinoic acid, driving immune tolerance.
Sun Feb 15 00:00:00 EST 2015
Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice.
Hypertension (Dallas, Tex. : 1979)
Yodoi K,Yamashita T,Sasaki N,Kasahara K,Emoto T,Matsumoto T,Kita T,Sasaki Y,Mizoguchi T,Sparwasser T,Hirata K
14-7101 was used in Flow cytometry/Cell sorting to suggest that Foxp3(+) Tregs may play a protective role in abdominal aortic aneurysm formation.
Wed Apr 01 00:00:00 EDT 2015
Efficacy and Tolerability of a GD2-Directed Trifunctional Bispecific Antibody in a Preclinical Model: Subcutaneous Administration Is Superior to Intravenous Delivery.
Molecular cancer therapeutics
Deppisch N,Ruf P,Eissler N,Neff F,Buhmann R,Lindhofer H,Mocikat R
14710181 was used in flow cytometry to optimize application routes for trifunctional bispecific antibodies against tumor-associated ganglioside GD2
Sat Aug 01 00:00:00 EDT 2015
Ly6C(high) monocytes control cerebral toxoplasmosis.
Journal of immunology (Baltimore, Md. : 1950)
Biswas A,Bruder D,Wolf SA,Jeron A,Mack M,Heimesaat MM,Dunay IR
14-7101 was used in Flow cytometry/Cell sorting to indicate the critical importance of recruited Ly6C monocytes upon cerebral toxoplasmosis.
Wed Apr 01 00:00:00 EDT 2015
Adaptive Immunity to Leukemia Is Inhibited by Cross-Reactive Induced Regulatory T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Manlove LS,Berquam-Vrieze KE,Pauken KE,Williams RT,Jenkins MK,Farrar MA
14710181 was used in flow cytometry to determine the mechanism by which BCR-ABL positive leukemia escapes immune surveillance
Thu Oct 15 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in ELISA
Wed Jul 01 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in ELISA
Wed Jul 01 00:00:00 EDT 2015
Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition.
The Journal of clinical investigation
Bhadra R,Moretto MM,Castillo JC,Petrovas C,Ferrando-Martinez S,Shokal U,Leal M,Koup RA,Eleftherianos I,Khan IA
14-7101 was used in Flow cytometry/Cell sorting to investigate the progressive loss of CD8+ T cell polyfunctionality during aging, using animals challenged with the obligate intracellular pathogen Encephalitozoon cuniculi.
Sun Jun 01 00:00:00 EDT 2014
Immunosuppressive monocytes: possible homeostatic mechanism to restrain chronic intestinal inflammation.
Journal of leukocyte biology
Kurmaeva E,Bhattacharya D,Goodman W,Omenetti S,Merendino A,Berney S,Pizarro T,Ostanin DV
14-7101 was used in Blocking experiments to characterise the interplay between colitis-induced myeloid cells and the CD4 T cell response.
Mon Sep 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation.
The Journal of experimental medicine
Zhang R,Lu G,Shen Y,Peng L,Zhu C,Cui M,Wang W,Arnaboldi P,Tang M,Gupta M,Qi CF,Jayaraman P,Zhu H,Jiang B,Chen SH,He JC,Ting AT,Zhou MM,Kuchroo VK,Morse HC,Ozato K,Sikora AG,Xiong H
14-7101 was used in an ELISA assay to study the effect of inducible nitric oxide synthase on T(H)17 cell differentiation.
Mon Jul 01 00:00:00 EDT 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Mucosal immunology
Manta C,Heupel E,Radulovic K,Rossini V,Garbi N,Riedel CU,Niess JH
Published figure using IL-10 monoclonal antibody (Product # 14-7101-81) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Neisseria gonorrhoeae induces a tolerogenic phenotype in macrophages to modulate host immunity.
Mediators of inflammation
Escobar A,Candia E,Reyes-Cerpa S,Villegas-Valdes B,Neira T,Lopez M,Maisey K,Tempio F,Ríos M,Acuña-Castillo C,Imarai M
14-7101 was used in an ELISA assay to determine whether N. gonorrhoeae directly conditions the phenotype of RAW 264.7 murine macrophage cell line and its response.
Thu Jun 05 00:00:00 EDT 2014
ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury.
Cell death & disease
Ishii H,Tanabe S,Ueno M,Kubo T,Kayama H,Serada S,Fujimoto M,Takeda K,Naka T,Yamashita T
14-7101 was used in Neutralization experiments to study the molecular mechanisms underlying the beneficial effects of pro-inflammatory Th1-conditioned cells following spinal cord injury.
Thu Jul 04 00:00:00 EDT 2013
Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage.
PloS one
Gahring LC,Enioutina EY,Myers EJ,Spangrude GJ,Efimova OV,Kelley TW,Tvrdik P,Capecchi MR,Rogers SW
14-7101 was used in Flow cytometry/Cell sorting to investigate how inflammatory responses are mechanistically modulated by nicotinic acetylcholine receptors.
Tue Aug 27 00:00:00 EDT 2013
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.
Nature
Yoshizaki A,Miyagaki T,DiLillo DJ,Matsushita T,Horikawa M,Kountikov EI,Spolski R,Poe JC,Leonard WJ,Tedder TF
14-7101 was used in Flow cytometry/Cell sorting to investigate how B10-cell IL-10 production and regulation of antigen-specific immune responses are controlled in vivo.
Thu Nov 08 00:00:00 EST 2012
Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates.
Immunity
Huang G,Wang Y,Shi LZ,Kanneganti TD,Chi H
14-7101 was used in Flow cytometry/Cell sorting to identify a regulatory circuit linking MKP-1 signaling in DCs, production of polarizing cytokines, and integration of DC-derived signals in responding T cells.
Fri Jul 22 00:00:00 EDT 2011
A role for leukocyte-derived IL-1RA in DC homeostasis revealed by increased susceptibility of IL-1RA-deficient mice to cutaneous leishmaniasis.
The Journal of investigative dermatology
Kautz-Neu K,Kostka SL,Dinges S,Iwakura Y,Udey MC,von Stebut E
14-7101 was used in Flow cytometry/Cell sorting to suggest that in addition to effects on Th education, IL-1α/β signalling also modulates DC homeostasis with increased signalling, leading to down-modulation of IL-12 synthesis and worsened disease outcome after infection with Leishmania major.
Mon Aug 01 00:00:00 EDT 2011
Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Weiss KA,Christiaansen AF,Fulton RB,Meyerholz DK,Varga SM
14-7101 was used in Flow cytometry/Cell sorting to evaluate the role of IL-10 in the modulation of the respiratory syncytial virus-specific immune response.
Thu Sep 15 00:00:00 EDT 2011
Retinal pericytes inhibit activated T cell proliferation.
Investigative ophthalmology & visual science
Tu Z,Li Y,Smith DS,Sheibani N,Huang S,Kern T,Lin F
14-7101 was used in Neutralization experiments to reveal a new function of retinal pericytes, and its regulation under hyperglycemic conditions.
Mon Nov 21 00:00:00 EST 2011
Retinal pericytes inhibit activated T cell proliferation.
Investigative ophthalmology & visual science
Tu Z,Li Y,Smith DS,Sheibani N,Huang S,Kern T,Lin F
14-7101 was used in Neutralization experiments to reveal a new function of retinal pericytes, and its regulation under hyperglycemic conditions.
Mon Nov 21 00:00:00 EST 2011
IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform.
The Journal of experimental medicine
Darrah PA,Hegde ST,Patel DT,Lindsay RW,Chen L,Roederer M,Seder RA
14-7101 was used in Flow cytometry/Cell sorting to delineate distinct mechanisms by which vaccines elicit protective Th1 responses and underscore the importance of multifunctional CD4(+) T cells.
Mon Jul 05 00:00:00 EDT 2010
Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery.
Plant biotechnology journal
Davoodi-Semiromi A,Schreiber M,Nalapalli S,Verma D,Singh ND,Banks RK,Chakrabarti D,Daniell H
14-7101 was used in Flow cytometry/Cell sorting to further investigate use of chloroplast-derived vaccines against major diseases.
Mon Feb 01 00:00:00 EST 2010
Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection.
Journal of immunology (Baltimore, Md. : 1950)
McCarl CA,Khalil S,Ma J,Oh-hora M,Yamashita M,Roether J,Kawasaki T,Jairaman A,Sasaki Y,Prakriya M,Feske S
14-7101 was used in Flow cytometry/Cell sorting to reaffirm the critical role of ORAI1 for T cell function, and provide important insights into the in vivo functions of CRAC channels for T cell-mediated immunity.
Mon Nov 15 00:00:00 EST 2010
Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis.
Journal of immunology (Baltimore, Md. : 1950)
Matsushita T,Horikawa M,Iwata Y,Tedder TF
14-7101 was used in Flow cytometry/Cell sorting to investigate how the regulatory functions of B10 cells and FoxP3(+) Tregs overlap or influence EAE immunopathogenesis independently.
Sun Aug 15 00:00:00 EDT 2010
Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg.
European journal of immunology
Shi Z,Okuno Y,Rifa'i M,Endharti AT,Akane K,Isobe K,Suzuki H
14-7101-81 was used in Enzyme-linked immunosorbent assay to suggest that human CD8(+)CXCR3(+) T cells are the counterparts of murine CD8(+)CD122(+) Treg.
Sat Aug 01 00:00:00 EDT 2009
Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression.
Journal of immunology (Baltimore, Md. : 1950)
Wu C,Rauch U,Korpos E,Song J,Loser K,Crocker PR,Sorokin LM
14-7101 was used in Flow cytometry/Cell sorting to propose a new direct cell-cell interaction-based mechanism regulating the expansion of Tregs during autoimmune and inflammatory processes.
Fri May 15 00:00:00 EDT 2009
The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Wilson JM,Ross WG,Agbai ON,Frazier R,Figler RA,Rieger J,Linden J,Ernst PB
14-7101 was used in Flow cytometry/Cell sorting to indicate that engagement of A(2B)AR modifies murine BMDC maturation and suggest that adenosine regulates CD4(+) T cell responses by selecting for DC with impaired immunogencity.
Wed Apr 15 00:00:00 EDT 2009
