Product References
Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4+ T cells.
Cell reports
Chatterjee D,Zhang Y,Ngassaki-Yoka CD,Dutilleul A,Khalfi S,Hernalsteens O,Wiche Salinas TR,Dias J,Chen H,Smail Y,Goulet JP,Bell B,Routy JP,Van Lint C,Ancuta P
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Tue Jun 27 00:00:00 EDT 2023
Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.
Journal of biochemical and molecular toxicology
Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2023
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Cell
Hoang TN,Pino M,Boddapati AK,Viox EG,Starke CE,Upadhyay AA,Gumber S,Nekorchuk M,Busman-Sahay K,Strongin Z,Harper JL,Tharp GK,Pellegrini KL,Kirejczyk S,Zandi K,Tao S,Horton TR,Beagle EN,Mahar EA,Lee MYH,Cohen J,Jean SM,Wood JS,Connor-Stroud F,Stammen RL,Delmas OM,Wang S,Cooney KA,Sayegh MN,Wang L,Filev PD,Weiskopf D,Silvestri G,Waggoner J,Piantadosi A,Kasturi SP,Al-Shakhshir H,Ribeiro SP,Sekaly RP,Levit RD,Estes JD,Vanderford TH,Schinazi RF,Bosinger SE,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to investigate the immunologic and virologic efficacy of baricitinib in a rhesus macaque model of SARS-CoV-2 infection.
Thu Jan 21 00:00:00 EST 2021
FABP4 facilitates inflammasome activation to induce the Treg/Th17 imbalance in preeclampsia via forming a positive feedback with IL-17A.
Molecular therapy. Nucleic acids
Chang GP,Yang XL,Liu W,Lin S,Yang SL,Zhao MY
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Fri Jun 04 00:00:00 EDT 2021
Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.
PloS one
Saenz SA,Local A,Carr T,Shakya A,Koul S,Hu H,Chourb L,Stedman J,Malley J,D'Agostino LA,Shanmugasundaram V,Malona J,Schwartz CE,Beebe L,Clements M,Rajaraman G,Cho J,Jiang L,Dubrovskiy A,Kreilein M,Shimanovich R,Hamann LG,Escoubet L,Ellis JM
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Wed Dec 29 00:00:00 EST 2021
YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis.
JCI insight
Lin J,Tang J,Lin J,He Y,Yu Z,Jiang R,Yang B,Ou Q
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Mon Nov 22 00:00:00 EST 2021
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques.
Nature communications
Harper J,Huot N,Micci L,Tharp G,King C,Rascle P,Shenvi N,Wang H,Galardi C,Upadhyay AA,Villinger F,Lifson J,Silvestri G,Easley K,Jacquelin B,Bosinger S,Müller-Trutwin M,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to generate terminally differentiated blood natural killer cells (NKG2a/clowCD16+) with potent human leukocyte antigen-E-restricted activity in response to SIV envelope peptides.
Mon May 17 00:00:00 EDT 2021
Neutrophil-Derived IL-17 Promotes Ventilator-Induced Lung Injury via p38 MAPK/MCP-1 Pathway Activation.
Frontiers in immunology
Liao X,Zhang W,Dai H,Jing R,Ye M,Ge W,Pei S,Pan L
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Immunohistochemistry (Paraffin)
Mon Feb 14 00:00:00 EST 2022
Th17/Treg imbalance modulates rat myocardial fibrosis and heart failure by regulating LOX expression.
Acta physiologica (Oxford, England)
Lu M,Qin X,Yao J,Yang Y,Zhao M,Sun L
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Neutralization
Sun Nov 01 00:00:00 EDT 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.
Cell reports. Medicine
Dhariwala MO,Karthikeyan D,Vasquez KS,Farhat S,Weckel A,Taravati K,Leitner EG,Clancy S,Pauli M,Piper ML,Cohen JN,Ashouri JF,Lowe MM,Rosenblum MD,Scharschmidt TC
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Tue Nov 17 00:00:00 EST 2020
Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
bioRxiv : the preprint server for biology
Hoang TN,Pino M,Boddapati AK,Viox EG,Starke CE,Upadhyay AA,Gumber S,Busman-Sahay K,Strongin Z,Harper JL,Tharp GK,Pellegrini KL,Kirejczyk S,Zandi K,Tao S,Horton TR,Beagle EN,Mahar EA,Lee MY,Cohen J,Jean SM,Wood JS,Connor-Stroud F,Stammen RL,Delmas OM,Wang S,Cooney KA,Sayegh MN,Wang L,Weiskopf D,Filev PD,Waggoner J,Piantadosi A,Kasturi SP,Al-Shakhshir H,Ribeiro SP,Sekaly RP,Levit RD,Estes JD,Vanderford TH,Schinazi RF,Bosinger SE,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to investigate the immunologic and virologic efficacy of baricitinib in a rhesus macaque model of SARS-CoV-2 infection.
Wed Sep 16 00:00:00 EDT 2020
Differential Dynamics of Regulatory T-Cell and Th17 Cell Balance in Mesenteric Lymph Nodes and Blood following Early Antiretroviral Initiation during Acute Simian Immunodeficiency Virus Infection.
Journal of virology
Yero A,Farnos O,Rabezanahary H,Racine G,Estaquier J,Jenabian MA
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination.
JCI insight
Sun B,Chang HH,Salinger A,Tomita B,Bawadekar M,Holmes CL,Shelef MA,Weerapana E,Thompson PR,Ho IC
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in ELISA
Thu Nov 14 00:00:00 EST 2019
CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis.
European journal of immunology
Affandi AJ,Silva-Cardoso SC,Garcia S,Leijten EFA,van Kempen TS,Marut W,van Roon JAG,Radstake TRDJ
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2018
Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.
Oncology letters
Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.
Mucosal immunology
McGary CS,Alvarez X,Harrington S,Cervasi B,Ryan ES,Iriele RI,Paganini S,Harper JL,Easley K,Silvestri G,Ansari AA,Lichterfeld M,Micci L,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to emphasize the importance of maintaining CCR6(+) and CD161(+) CD4(+) T-cell homeostasis, particularly in the mucosa, to prevent disease progression during pathogenic HIV/SIV infection.
Sat Jul 01 00:00:00 EDT 2017
Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10.
Journal of immunology (Baltimore, Md. : 1950)
Zanin-Zhorov A,Weiss JM,Trzeciak A,Chen W,Zhang J,Nyuydzefe MS,Arencibia C,Polimera S,Schueller O,Fuentes-Duculan J,Bonifacio KM,Kunjravia N,Cueto I,Soung J,Fleischmann RM,Kivitz A,Lebwohl M,Nunez M,Woodson J,Smith SL,West RF,Berger M,Krueger JG,Ryan JL,Waksal SD
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in ELISA
Mon May 15 00:00:00 EDT 2017
Enhancing the toolbox to study IL-17A in cattle and sheep.
Veterinary research
Wattegedera SR,Corripio-Miyar Y,Pang Y,Frew D,McNeilly TN,Palarea-Albaladejo J,McInnes CJ,Hope JC,Glass EJ,Entrican G
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Sat Apr 08 00:00:00 EDT 2017
Berberine exerts an anti-inflammatory role in ocular Behcet's disease.
Molecular medicine reports
Yang Y,Wang Q,Xie M,Liu P,Qi X,Liu X,Li Z
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis.
Nature communications
Hu D,Notarbartolo S,Croonenborghs T,Patel B,Cialic R,Yang TH,Aschenbrenner D,Andersson KM,Gattorno M,Pham M,Kivisakk P,Pierre IV,Lee Y,Kiani K,Bokarewa M,Tjon E,Pochet N,Sallusto F,Kuchroo VK,Weiner HL
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Fri Nov 17 00:00:00 EST 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Thu Aug 03 00:00:00 EDT 2017
CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus.
Frontiers in immunology
Zhu H,Hu F,Sun X,Zhang X,Zhu L,Liu X,Li X,Xu L,Shi L,Gan Y,Su Y
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in ELISA
Wed Nov 20 00:00:00 EST 2019
CD16+ Monocyte Subset Was Enriched and Functionally Exacerbated in Driving T-Cell Activation and B-Cell Response in Systemic Lupus Erythematosus.
Frontiers in immunology
Zhu H,Hu F,Sun X,Zhang X,Zhu L,Liu X,Li X,Xu L,Shi L,Gan Y,Su Y
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in ELISA
Wed Nov 20 00:00:00 EST 2019
Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques.
PLoS pathogens
Ryan ES,Micci L,Fromentin R,Paganini S,McGary CS,Easley K,Chomont N,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to show that intestinal IL-17 producing cell function is severely impaired by SIV infection and is not fully normalized despite effective ART.
Mon Feb 01 00:00:00 EST 2016
Chronic mucocutaneous candidiasis: characterization of a family with STAT-1 gain-of-function and development of an ex-vivo assay for Th17 deficiency of diagnostic utility.
Clinical and experimental immunology
Dhalla F,Fox H,Davenport EE,Sadler R,Anzilotti C,van Schouwenburg PA,Ferry B,Chapel H,Knight JC,Patel SY
53-7179 was used in Flow cytometry/Cell sorting to characterise the chronic mucocutaneous candidiasis of a family with a STAT-10 gain-of-function mutation, and develop an ex-vivo assay for T helper type 17 deficiency.
Sun May 01 00:00:00 EDT 2016
Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion.
Arthritis research & therapy
Noack M,Ndongo-Thiam N,Miossec P
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis.
International journal of molecular medicine
Liang DY,Hou YQ,Luo LJ,Ao L
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Immunofluorescence
Fri Jul 01 00:00:00 EDT 2016
Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis.
International journal of molecular medicine
Liang DY,Hou YQ,Luo LJ,Ao L
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Immunofluorescence
Fri Jul 01 00:00:00 EDT 2016
T-helper 17 cell polarization in pulmonary arterial hypertension.
Chest
Hautefort A,Girerd B,Montani D,Cohen-Kaminsky S,Price L,Lambrecht BN,Humbert M,Perros F
53-7179 was used in Flow cytometry/Cell sorting to study T helper 17 cell immune polarization in patients with pulmonary arterial hypertension.
Mon Jun 01 00:00:00 EDT 2015
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy.
Journal of immunology (Baltimore, Md. : 1950)
Rasouli J,Ciric B,Imitola J,Gonnella P,Hwang D,Mahajan K,Mari ER,Safavi F,Leist TP,Zhang GX,Rostami A
53-7179 was used in Flow cytometry/Cell sorting to characterise GM-CSF production by T cells of MS patients and to determine the effect of IFN-β therapy on its production.
Mon Jun 01 00:00:00 EDT 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Tue Sep 08 00:00:00 EDT 2015
Fiber composite slices for multiplexed immunoassays.
Biomicrofluidics
Kim J,Bae S,Song S,Chung K,Kwon S
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Radioimmune Assays
Wed Jul 01 00:00:00 EDT 2015
Fiber composite slices for multiplexed immunoassays.
Biomicrofluidics
Kim J,Bae S,Song S,Chung K,Kwon S
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Radioimmune Assays
Wed Jul 01 00:00:00 EDT 2015
Schistosoma mansoni Infection in Ugandan Men Is Associated with Increased Abundance and Function of HIV Target Cells in Blood, but Not the Foreskin: A Cross-sectional Study.
PLoS neglected tropical diseases
Prodger JL,Ssemaganda A,Ssetaala A,Kitandwe PK,Muyanja E,Mpendo J,Nanvubya A,Wambuzi M,Nielsen L,Kiwanuka N,Kaul R
53-7179 was used in Flow cytometry/Cell sorting to hypothesize that immune activation from this gastrointestinal mucosa infection would increase highly HIV-susceptible CD4 T cell subsets in the blood.
Mon Mar 28 00:00:00 EDT 2016
An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.
Immunity
Boisson B,Wang C,Pedergnana V,Wu L,Cypowyj S,Rybojad M,Belkadi A,Picard C,Abel L,Fieschi C,Puel A,Li X,Casanova JL
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Thu Oct 17 00:00:00 EDT 2013
Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes.
The Journal of allergy and clinical immunology
Chan YR,Chen K,Duncan SR,Lathrop KL,Latoche JD,Logar AJ,Pociask DA,Wahlberg BJ,Ray P,Ray A,Pilewski JM,Kolls JK
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Immunofluorescence
Mon Apr 01 00:00:00 EDT 2013
Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21.
PLoS pathogens
Pallikkuth S,Micci L,Ende ZS,Iriele RI,Cervasi B,Lawson B,McGary CS,Rogers KA,Else JG,Silvestri G,Easley K,Estes JD,Villinger F,Pahwa S,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to discover whether IL-21 administration improves mucosal function in the context of pathogenic HIV/SIV infections.
Tue Feb 18 00:00:00 EST 2014
Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection.
PLoS pathogens
Sundaravaradan V,Saleem R,Micci L,Gasper MA,Ortiz AM,Else J,Silvestri G,Paiardini M,Aitchison JD,Sodora DL
53-7179 was used in Flow cytometry/Cell sorting to evaluate double-negative T cells for their potential to fulfil a role as helper T cells in SIV-infected sooty mangabeys.
Fri Jan 17 00:00:00 EST 2014
Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).
Arthritis research & therapy
Abdulahad WH,Lepse N,Stegeman CA,Huitema MG,Doornbos-van der Meer B,Tadema H,Rutgers A,Limburg PC,Kallenberg CG,Heeringa P
53-7179 was used in Flow cytometry/Cell sorting to explore a possible role for IL-21 producing Th-cells in the immunopathogenesis of granulomatosis with polyangiitis.
Fri Nov 14 00:00:00 EST 2014
IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tang XZ,Jo J,Tan AT,Sandalova E,Chia A,Tan KC,Lee KH,Gehring AJ,De Libero G,Bertoletti A
53-7179 was used in Flow cytometry/Cell sorting to investigate the function of human mucosal-associated invariant T (MAIT) cells in the human liver and peripheral blood, showing that MAIT cells express high levels of IL-7 receptor, which allows regulation of TCR activation of MAIT cells.
Mon Apr 01 00:00:00 EDT 2013
Intercellular adhesion molecule 1 mediates migration of Th1 and Th17 cells across human retinal vascular endothelium.
Investigative ophthalmology & visual science
Bharadwaj AS,Schewitz-Bowers LP,Wei L,Lee RW,Smith JR
53-7179 was used in Flow cytometry/Cell sorting to investigate the ability of human Th1- and Th17-polarised cells to cross a simulated human retinal endothelium, and examined the role of IgG superfamily members in this process.
Wed Oct 23 00:00:00 EDT 2013
Paucity of IL-21-producing CD4(+) T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques.
Blood
Micci L,Cervasi B,Ende ZS,Iriele RI,Reyes-Aviles E,Vinton C,Else J,Silvestri G,Ansari AA,Villinger F,Pahwa S,Estes JD,Brenchley JM,Paiardini M
53-7179 was used in Flow cytometry/Cell sorting to investigate the phenotype, functions, and frequency of blood and intestinal IL-21-producing CD4+ T cells in two nonhuman primate models of SIV infection.
Thu Nov 08 00:00:00 EST 2012
Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.
PloS one
Zhang L,Li YG,Li YH,Qi L,Liu XG,Yuan CZ,Hu NW,Ma DX,Li ZF,Yang Q,Li W,Li JM
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Flow Cytometry
Fri Jul 27 00:00:00 EDT 2012
Matrix metalloproteinase-2 conditions human dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and OX40L-dependent pathway.
Cancer cell
Godefroy E,Manches O,Dréno B,Hochman T,Rolnitzky L,Labarrière N,Guilloux Y,Goldberg J,Jotereau F,Bhardwaj N
53-7179 was used in Flow cytometry/Cell sorting to reveal that MMP2-conditioned DCs prime Th2 responses against several melanoma-associated antigens, highlighting the potential of MMP2 as a target antigen in melanoma.
Tue Mar 08 00:00:00 EST 2011
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.
The Journal of experimental medicine
Liu L,Okada S,Kong XF,Kreins AY,Cypowyj S,Abhyankar A,Toubiana J,Itan Y,Audry M,Nitschke P,Masson C,Toth B,Flatot J,Migaud M,Chrabieh M,Kochetkov T,Bolze A,Borghesi A,Toulon A,Hiller J,Eyerich S,Eyerich K,Gulácsy V,Chernyshova L,Chernyshov V,Bondarenko A,Grimaldo RM,Blancas-Galicia L,Beas IM,Roesler J,Magdorf K,Engelhard D,Thumerelle C,Burgel PR,Hoernes M,Drexel B,Seger R,Kusuma T,Jansson AF,Sawalle-Belohradsky J,Belohradsky B,Jouanguy E,Bustamante J,Bué M,Karin N,Wildbaum G,Bodemer C,Lortholary O,Fischer A,Blanche S,Al-Muhsen S,Reichenbach J,Kobayashi M,Rosales FE,Lozano CT,Kilic SS,Oleastro M,Etzioni A,Traidl-Hoffmann C,Renner ED,Abel L,Picard C,Maródi L,Boisson-Dupuis S,Puel A,Casanova JL
53-7179 was used in Flow cytometry/Cell sorting to identify and investigate heterozygous germline mutations in patients with candidiasis disease.
Mon Aug 01 00:00:00 EDT 2011
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.
The Journal of experimental medicine
Liu L,Okada S,Kong XF,Kreins AY,Cypowyj S,Abhyankar A,Toubiana J,Itan Y,Audry M,Nitschke P,Masson C,Toth B,Flatot J,Migaud M,Chrabieh M,Kochetkov T,Bolze A,Borghesi A,Toulon A,Hiller J,Eyerich S,Eyerich K,Gulácsy V,Chernyshova L,Chernyshov V,Bondarenko A,Grimaldo RM,Blancas-Galicia L,Beas IM,Roesler J,Magdorf K,Engelhard D,Thumerelle C,Burgel PR,Hoernes M,Drexel B,Seger R,Kusuma T,Jansson AF,Sawalle-Belohradsky J,Belohradsky B,Jouanguy E,Bustamante J,Bué M,Karin N,Wildbaum G,Bodemer C,Lortholary O,Fischer A,Blanche S,Al-Muhsen S,Reichenbach J,Kobayashi M,Rosales FE,Lozano CT,Kilic SS,Oleastro M,Etzioni A,Traidl-Hoffmann C,Renner ED,Abel L,Picard C,Maródi L,Boisson-Dupuis S,Puel A,Casanova JL
53-7179 was used in Flow cytometry/Cell sorting to identify and investigate heterozygous germline mutations in patients with candidiasis disease.
Mon Aug 01 00:00:00 EDT 2011
Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jones GW,Stumhofer JS,Foster T,Twohig JP,Hertzog P,Topley N,Williams AS,Hunter CA,Jenkins BJ,Wang EC,Jones SA
53-7179 was used in Flow cytometry/Cell sorting to investigate the relationship between T-cell activation and TL1A responsiveness.
Sat Jan 01 00:00:00 EST 2011
Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.
Arthritis research & therapy
Dolff S,Abdulahad WH,Westra J,Doornbos-van der Meer B,Limburg PC,Kallenberg CG,Bijl M
53-7179 was used in Flow cytometry/Cell sorting to reveal a pivotal role of IL-21 in the pathogenesis of SLE.
Thu Dec 13 00:00:00 EST 2012
Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production.
Blood
Volpe E,Touzot M,Servant N,Marloie-Provost MA,Hupé P,Barillot E,Soumelis V
53-7179 was used in Flow cytometry/Cell sorting to demonstrate that interleukin (IL)-17 and IL-22 are differentially regulated during cytokine-induced T helper cell differentiation.
Thu Oct 22 00:00:00 EDT 2009
A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Kap YS,van Meurs M,van Driel N,Koopman G,Melief MJ,Brok HP,Laman JD,'t Hart BA
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Immunohistochemistry
Tue Dec 01 00:00:00 EST 2009
Interleukin-12 is the optimum cytokine to expand human Th17 cells in vitro.
Clinical and vaccine immunology : CVI
Nady S,Ignatz-Hoover J,Shata MT
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in ELISA
Mon Jun 01 00:00:00 EDT 2009
Interleukin-12 is the optimum cytokine to expand human Th17 cells in vitro.
Clinical and vaccine immunology : CVI
Nady S,Ignatz-Hoover J,Shata MT
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in ELISA
Mon Jun 01 00:00:00 EDT 2009
Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha.
Arthritis research & therapy
Parsonage G,Filer A,Bik M,Hardie D,Lax S,Howlett K,Church LD,Raza K,Wong SH,Trebilcock E,Scheel-Toellner D,Salmon M,Lord JM,Buckley CD
Published figure using IL-17A monoclonal antibody (Product # 53-7179-42) in Immunofluorescence
Tue Sep 23 00:00:00 EDT 2008
Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression.
The Journal of experimental medicine
Hartigan-O'Connor DJ,Abel K,McCune JM
53-7179 was used in Flow cytometry/Cell sorting to suggest that suppression of SIV-specific CD4+ T-cell responses by infant macaque regulatory T-cells facilitates rapid disease progression.
Mon Oct 29 00:00:00 EDT 2007
