Product References
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Metformin attenuates high-fat diet induced metabolic syndrome related osteoarthritis through inhibition of prostaglandins.
Frontiers in cell and developmental biology
Liu X,Guo Q,Wang L,Gu Y,Meng S,Gu Y,Yu B
14-5920-82 was used in Immunohistochemistry (Frozen) to demonstrate prostaglandins secreted by macrophages may be a key reason for high-fat diet induced aberrant bone formation and metformin is a promising therapy for high-fat diet induced osteoarthritis.
Sun May 21 00:00:00 EDT 2023
Plexin D1 mediates disturbed flow-induced M1 macrophage polarization in atherosclerosis.
Heliyon
Zhang S,Zhang Y,Zhang P,Wei Z,Ma M,Wang W,Tong W,Tian F,Hui H,Tian J,Chen Y
14-5920-82 was used in Immunohistochemistry to identify the role of PLXND1 in site-specific atherosclerosis.
Thu Jun 01 00:00:00 EDT 2023
Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.
Immunity
Formaglio P,Alabdullah M,Siokis A,Handschuh J,Sauerland I,Fu Y,Krone A,Gintschel P,Stettin J,Heyde S,Mohr J,Philipsen L,Schröder A,Robert PA,Zhao G,Khailaie S,Dudeck A,Bertrand J,Späth GF,Kahlfuß S,Bousso P,Schraven B,Huehn J,Binder S,Meyer-Hermann M,Müller AJ
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Tue Dec 14 00:00:00 EST 2021
Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection.
Immunity
Xu W,Snell LM,Guo M,Boukhaled G,Macleod BL,Li M,Tullius MV,Guidos CJ,Tsao MS,Divangahi M,Horwitz MA,Liu J,Brooks DG
14-5920-82 was used in Miscellaneous to examine how chronic viral infections alter the pulmonary microenvironment to foster coinfection and worsen disease severity.
Tue Mar 09 00:00:00 EST 2021
Prostaglandin E3 attenuates macrophage-associated inflammation and prostate tumour growth by modulating polarization.
Journal of cellular and molecular medicine
Cui J,Shan K,Yang Q,Qi Y,Qu H,Li J,Wang R,Jia L,Chen W,Feng N,Chen YQ
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Regulation of the long noncoding RNA XIST on the inflammatory polarization of microglia in cerebral infarction.
Experimental and therapeutic medicine
Zhang M,Yang JK,Ma J
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 2021
Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization.
Stem cell research & therapy
Dong B,Wang C,Zhang J,Zhang J,Gu Y,Guo X,Zuo X,Pan H,Hsu AC,Wang G,Wang F
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed Mar 24 00:00:00 EDT 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed Oct 27 00:00:00 EDT 2021
Annexin A1 protects against cerebral ischemia-reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway.
Journal of neuroinflammation
Xu X,Gao W,Li L,Hao J,Yang B,Wang T,Li L,Bai X,Li F,Ren H,Zhang M,Zhang L,Wang J,Wang D,Zhang J,Jiao L
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Immunocytochemistry
Sat May 22 00:00:00 EDT 2021
PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway.
Frontiers in immunology
Kong F,Sun K,Zhu J,Li F,Lin F,Sun X,Luo X,Ren C,Lu L,Zhao S,Sun J,Wang Y,Shi J
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation.
Nature communications
Iizasa E,Chuma Y,Uematsu T,Kubota M,Kawaguchi H,Umemura M,Toyonaga K,Kiyohara H,Yano I,Colonna M,Sugita M,Matsuzaki G,Yamasaki S,Yoshida H,Hara H
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Fri Apr 16 00:00:00 EDT 2021
Computational modeling reveals a key role for polarized myeloid cells in controlling osteoclast activity during bone injury repair.
Scientific reports
Lo CH,Baratchart E,Basanta D,Lynch CC
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Mon Mar 15 00:00:00 EDT 2021
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer.
Journal for immunotherapy of cancer
Lee SJ,Yang H,Kim WR,Lee YS,Lee WS,Kong SJ,Lee HJ,Kim JH,Cheon J,Kang B,Chon HJ,Kim C
14-5920-82 was used in Flow Cytometry to elucidate the immune-evasion mechanisms during the peritoneal carcinomatosis of colon cancer and developed a novel immunotherapy by activating the stimulator of interferon genes (STING) pathway.
Tue Jun 01 00:00:00 EDT 2021
The thrombin receptor modulates astroglia-neuron trophic coupling and neural repair after spinal cord injury.
Glia
Kim HN,Triplet EM,Radulovic M,Bouchal S,Kleppe LS,Simon WL,Yoon H,Scarisbrick IA
14-5920-82 was used in Flow Cytometry, Immunocytochemistry, Western Blot, Immunohistochemistry to demonstrate unique modulatory roles for PAR1 in regulating glial-neuron interactions, including the capacity for neurotrophic factor signaling, and underscore its position at neurobiological intersections critical for the response of the CNS to injury and the capacity for regenerative repair and restoration of function.
Wed Sep 01 00:00:00 EDT 2021
Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.
British journal of pharmacology
De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2020
Anticancer Activity of Liquid Treated with Microwave Plasma-Generated Gas through Macrophage Activation.
Oxidative medicine and cellular longevity
Lee CB,Seo IH,Chae MW,Park JW,Choi EH,Uhm HS,Baik KY
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis.
Journal of leukocyte biology
Rodrigues TS,Alvarez ARP,Gembre AF,Forni MFPAD,de Melo BMS,Alves Filho JCF,Câmara NOS,Bonato VLD
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2020
Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy.
Nature communications
Baumann D,Hägele T,Mochayedi J,Drebant J,Vent C,Blobner S,Noll JH,Nickel I,Schumacher C,Boos SL,Daniel AS,Wendler S,Volkmar M,Strobel O,Offringa R
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury.
Cell reports
Giri J,Das R,Nylen E,Chinnadurai R,Galipeau J
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Tue Feb 11 00:00:00 EST 2020
AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells.
Cancer research
Trillo-Tinoco J,Sierra RA,Mohamed E,Cao Y,de Mingo-Pulido Á,Gilvary DL,Anadon CM,Costich TL,Wei S,Flores ER,Ruffell B,Conejo-Garcia JR,Rodriguez PC
14-5920-82 was used in Flow cytometry/Cell sorting to elucidate the intrinsic interaction between the expression of AMP-activated protein kinase alpha (AMPKα) and the immunoregulatory activity of myeloid-derived suppressor cells in tumors.
Tue Oct 01 00:00:00 EDT 2019
Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection.
PLoS pathogens
Santecchia I,Vernel-Pauillac F,Rasid O,Quintin J,Gomes-Solecki M,Boneca IG,Werts C
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
1,25‑Dihydroxy‑Vitamin D3 induces macrophage polarization to M2 by upregulating T‑cell Ig‑mucin‑3 expression.
Molecular medicine reports
Liang S,Cai J,Li Y,Yang R
14-5920 was used in Western Blotting to indicate that upregulation of Tim-3 can induce immunosuppression by 1,25(OH)2D3 and that Tim-3 can also induce polarisation to M2.
Wed May 01 00:00:00 EDT 2019
1,25‑Dihydroxy‑Vitamin D3 induces macrophage polarization to M2 by upregulating T‑cell Ig‑mucin‑3 expression.
Molecular medicine reports
Liang S,Cai J,Li Y,Yang R
14-5920 was used in Western Blotting to indicate that upregulation of Tim-3 can induce immunosuppression by 1,25(OH)2D3 and that Tim-3 can also induce polarisation to M2.
Wed May 01 00:00:00 EDT 2019
Adoptive transfer of Trichinella spiralis-activated macrophages can ameliorate both Th1- and Th2-activated inflammation in murine models.
Scientific reports
Kang SA,Park MK,Park SK,Choi JH,Lee DI,Song SM,Yu HS
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Thu Apr 25 00:00:00 EDT 2019
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.
Nature communications
Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Fri Feb 22 00:00:00 EST 2019
Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice.
Foods (Basel, Switzerland)
Chen L,Zhang J,Suo H,Wang W,Wang H,Zhang Y,Hu Q,Zhao X,Li J
14-5920-82 was used in Western Blot to compare the prevention effects of Shuidouchi with different fermentation times on constipation in mice.
Fri Mar 01 00:00:00 EST 2019
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.
Nature communications
Chen D,Xie J,Fiskesund R,Dong W,Liang X,Lv J,Jin X,Liu J,Mo S,Zhang T,Cheng F,Zhou Y,Zhang H,Tang K,Ma J,Liu Y,Huang B
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed Feb 28 00:00:00 EST 2018
Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.
Nature communications
Chen D,Xie J,Fiskesund R,Dong W,Liang X,Lv J,Jin X,Liu J,Mo S,Zhang T,Cheng F,Zhou Y,Zhang H,Tang K,Ma J,Liu Y,Huang B
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Wed Feb 28 00:00:00 EST 2018
Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression.
Oncotarget
Simonneau M,Frouin E,Huguier V,Jermidi C,Jégou JF,Godet J,Barra A,Paris I,Levillain P,Cordier-Dirikoc S,Pedretti N,Bernard FX,Lecron JC,Morel F,Favot L
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Fri Nov 23 00:00:00 EST 2018
Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.
Nature communications
Yi S,Zhai J,Niu R,Zhu G,Wang M,Liu J,Huang H,Wang Y,Jing X,Kang L,Song W,Shi Y,Tang H
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Mon Sep 24 00:00:00 EDT 2018
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.
Nature cell biology
Giampazolias E,Zunino B,Dhayade S,Bock F,Cloix C,Cao K,Roca A,Lopez J,Ichim G,Proïcs E,Rubio-Patiño C,Fort L,Yatim N,Woodham E,Orozco S,Taraborrelli L,Peltzer N,Lecis D,Machesky L,Walczak H,Albert ML,Milling S,Oberst A,Ricci JE,Ryan KM,Blyth K,Tait SWG
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy.
Frontiers in immunology
Chavez-Galan L,Vesin D,Uysal H,Blaser G,Benkhoucha M,Ryffel B,Quesniaux VFJ,Garcia I
14-5920 was used in Flow cytometry/Cell sorting to provide insight into the crucial role played by the transmembrane TNF/TNF receptor 2 pathway in myeloid-derived suppressor cell suppressive activity required during acute pleural infection to attenuate excessive inflammation generated by the infection.
Wed Nov 20 00:00:00 EST 2019
Depletion of microglia exacerbates postischemic inflammation and brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections.
Journal of immunology (Baltimore, Md. : 1950)
Leech JM,Lacey KA,Mulcahy ME,Medina E,McLoughlin RM
14592082 was used in flow cytometry to define the functions of IL-10 during Staphylococcus aureus
Wed Mar 15 00:00:00 EDT 2017
Phenotypic switch in lung interstitial macrophage polarization in an ovalbumin-induced mouse model of asthma.
Experimental and therapeutic medicine
Nie H,Wang A,He Q,Yang Q,Liu L,Zhang G,Huang Y,Ding X,Yu H,Hu S
14-5920-82 was used in Flow Cytometry, Western Blot to observe the phenotypic characteristics of lung interstitial macrophages in an ovalbumin-induced mouse model of asthma.
Tue Aug 01 00:00:00 EDT 2017
Phenotypic switch in lung interstitial macrophage polarization in an ovalbumin-induced mouse model of asthma.
Experimental and therapeutic medicine
Nie H,Wang A,He Q,Yang Q,Liu L,Zhang G,Huang Y,Ding X,Yu H,Hu S
14-5920-82 was used in Flow Cytometry, Western Blot to observe the phenotypic characteristics of lung interstitial macrophages in an ovalbumin-induced mouse model of asthma.
Tue Aug 01 00:00:00 EDT 2017
Phenotypic switch in lung interstitial macrophage polarization in an ovalbumin-induced mouse model of asthma.
Experimental and therapeutic medicine
Nie H,Wang A,He Q,Yang Q,Liu L,Zhang G,Huang Y,Ding X,Yu H,Hu S
14-5920-82 was used in Flow Cytometry, Western Blot to observe the phenotypic characteristics of lung interstitial macrophages in an ovalbumin-induced mouse model of asthma.
Tue Aug 01 00:00:00 EDT 2017
TGF-β receptor 1 inhibition prevents stenosis of tissue-engineered vascular grafts by reducing host mononuclear phagocyte activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee YU,de Dios Ruiz-Rosado J,Mahler N,Best CA,Tara S,Yi T,Shoji T,Sugiura T,Lee AY,Robledo-Avila F,Hibino N,Pober JS,Shinoka T,Partida-Sanchez S,Breuer CK
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation.
Infection and immunity
Osterloh A,Papp S,Moderzynski K,Kuehl S,Richardt U,Fleischer B
14592082 was used in flow cytometry to report the course of Rickettsia typhi infection in RAG1 knockout mice
Sun May 01 00:00:00 EDT 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2016
Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells.
PLoS neglected tropical diseases
Papp S,Moderzynski K,Rauch J,Heine L,Kuehl S,Richardt U,Mueller H,Fleischer B,Osterloh A
14592082 was used in flow cytometry to investigate the contribution of neutrophils and macrophages during Rickettsia typhi infection
Mon Aug 01 00:00:00 EDT 2016
Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma.
Oncotarget
McFarland BC,Marks MP,Rowse AL,Fehling SC,Gerigk M,Qin H,Benveniste EN
14592082 was used in flow cytometry to observe that Suppressor of Cytokine Signaling 3-deficient bone marrow-derived macrophages display enhanced and prolonged expression of pro-inflammatory M1 cytokines when exposed to glioma tumor cell conditioned medium in vitro
Tue Apr 12 00:00:00 EDT 2016
OGR1/GPR68 Modulates the Severity of Experimental Autoimmune Encephalomyelitis and Regulates Nitric Oxide Production by Macrophages.
PloS one
D'Souza CA,Zhao FL,Li X,Xu Y,Dunn SE,Zhang L
14-5920 was used in Flow cytometry/Cell sorting to suggest that ovarian cancer G protein-coupled receptor 1 plays a key role in regulating T cell responses during autoimmunity.
Tue Jul 19 00:00:00 EDT 2016
Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models.
Cancer immunology research
Shen L,Sundstedt A,Ciesielski M,Miles KM,Celander M,Adelaiye R,Orillion A,Ciamporcero E,Ramakrishnan S,Ellis L,Fenstermaker R,Abrams SI,Eriksson H,Leanderson T,Olsson A,Pili R
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Sun Feb 01 00:00:00 EST 2015
Commensal Gram-positive bacteria initiates colitis by inducing monocyte/macrophage mobilization.
Mucosal immunology
Nakanishi Y,Sato T,Ohteki T
Thu Jan 01 00:00:00 EST 2015
Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo.
Frontiers in cellular neuroscience
Smolders S,Smolders SM,Swinnen N,Gärtner A,Rigo JM,Legendre P,Brône B
Published figure using iNOS monoclonal antibody (Product # 14-5920-82) in Flow Cytometry
Mon Aug 24 00:00:00 EDT 2015