TEM Accessories and Upgrades

Additional upgrades for Talos transmission electron microscopes upgrades

	Panther STEM Electron Detection Ideal solution to image beam-sensitive materials High signal-to-noise ratio, reducing the image distortion
	Automated (nano) Particle Workflow (APW) Highly automated workflow from image acquisition to data analysis Run your TEM 24/7 unattended and make the most of overnight or weekend microscope usage
	AutoScript: Python Scripting environment Powerful Python scripting (API) for TEM, allowing repetitive work to be done faster, more accurately, and with fewer mistakes
	Correlative Electron Microscopy Software: MAPS Completely automated solution for generating high-quality, multi-scale image of large overview while preserving the context of observations Correlation of images from different microscopes, including imported images from third-party instruments using the integrated Bio-Formats Library
	4D-STEM (Scanning transmission electron microscopy) Thermo Scientific EMPAD Detector for 4D STEM application, enabling detailed access to information on strain, orientation, and electric or magnetic fields (center of mass analysis) Optimum integration on Talos TEM platforms without loss of performance on dedicated mounting port
	Thermo Scientific Ceta-S Camera High-speed, high-sensitivity imaging solution for beam-sensitive materials Dynamic movie recording of in situ experiments Enables easier and more accurate quantitative operation with faster time-to-data
	Micro-electron diffraction (MicroED) package Complete solution for fast, high-resolution 3D structure determination Typical applications include medicinal chemistry, catalyst research, and metal-organic frameworks (MOF)
	Differential phase contrast/integrated differential phase contrast (DPC/iDPC) STEM The iDPC STEM method exposes low-Z elements with bright contrast and dark backgrounds iDPC-STEM images have a higher signal-to-noise ratio, providing the possibility of low-dose imaging, which is crucial for beam-sensitive materials and charging samples
	Talos Guru App Quickly train new users within days instead of weeks Receive guidance for infrequently used techniques Get help with complex sample orientation and alignment

Additional upgrades for Themis Transmission Electron Microscopes upgrades

	Panther STEM Electron Detection Ideal solution to image beam-sensitive materials High signal-to-noise ratio, reducing the image distortion
	Automated (nano) Particle Workflow (APW) Highly automated workflow from image acquisition to data analysis Run your TEM 24/7 unattended and make the most of overnight or weekend microscope usage
	AutoScript: Python Scripting environment Powerful Python scripting (API) for TEM, allowing repetitive work to be done faster, more accurately, and with fewer mistakes
	Correlative Electron Microscopy Software: MAPS Completely automated solution for generating high-quality, multi-scale image of large overview while preserving the context of observations Correlation of images from different microscopes, including imported images from third-party instruments using the integrated Bio-Formats Library
	4D-STEM (Scanning transmission electron microscopy) Thermo Scientific EMPAD Detector for 4D STEM application, enabling detailed access to information on strain, orientation, and electric or magnetic fields (center of mass analysis) Optimum integration on Talos TEM platforms without loss of performance on dedicated mounting port
	Thermo Scientific Ceta-S Camera High-speed, high-sensitivity imaging solution for beam-sensitive materials Dynamic movie recording of in situ experiments Enables easier and more accurate quantitative operation with faster time-to-data
	Micro-electron diffraction (MicroED) package Complete solution for fast, high-resolution 3D structure determination Typical applications include medicinal chemistry, catalyst research, and metal-organic frameworks (MOF)
	Differential phase contrast/integrated differential phase contrast (DPC/iDPC) STEM The iDPC STEM method exposes low-Z elements with bright contrast and dark backgrounds iDPC-STEM images have a higher signal-to-noise ratio, providing the possibility of low-dose imaging, which is crucial for beam-sensitive materials and charging samples

Additional upgrades for Spectra transmission electron microscopes upgrades

	AutoScript: Python Scripting environment Powerful Python scripting (API) for TEM, allowing repetitive work to be done faster, more accurately, and with fewer mistakes
	Correlative Electron Microscopy Software: MAPS Completely automated solution for generating high-quality, multi-scale image of large overview while preserving the context of observations Correlation of images from different microscopes, including imported images from third-party instruments using the integrated Bio-Formats Library
	4D-STEM (Scanning transmission electron microscopy) Thermo Scientific EMPAD Detector for 4D STEM application, enabling detailed access to information on strain, orientation, and electric or magnetic fields (center of mass analysis) Optimum integration on Talos TEM platforms without loss of performance on dedicated mounting port
	Thermo Scientific Ceta-S Camera High-speed, high-sensitivity imaging solution for beam-sensitive materials Dynamic movie recording of in situ experiments Enables easier and more accurate quantitative operation with faster time-to-data
	Micro-electron diffraction (MicroED) package Complete solution for fast, high-resolution 3D structure determination Typical applications include medicinal chemistry, catalyst research, and metal-organic frameworks (MOF)
	Differential phase contrast/integrated differential phase contrast (DPC/iDPC) STEM The iDPC STEM method exposes low-Z elements with bright contrast and dark backgrounds iDPC-STEM images have a higher signal-to-noise ratio, providing the possibility of low-dose imaging, which is crucial for beam-sensitive materials and charging samples

Hardware upgrades for Thermo Scientific cryo-TEMs

	Selectris and Selectris X Imaging Filters Thermo Scientific Selectris and Selectris X Imaging Filters improve TEM contrast by removing noise caused by inelastically scattered electrons, producing an increased signal-to-noise ratio Benefit: Better performance in less time
	Falcon 4i Direct Electron Detector The Thermo Scientific Falcon 4i Direct Electron Detector delivers best-in-class image quality and fast data collection Benefit: Increased image collection per hour
	Fringe-free imaging (FFI) Fringe-free imaging (FFI) eliminates fringes at the edge of the beam so you can acquire more usable images per foil hole to enhance overall throughput Benefit: Improved throughput; more images can be collected per hole
	E-CFEG The Thermo Scientific E-CFEG is a cold field emission gun with a low-energy spread that increases image contrast and enables atomic-resolution imaging Benefit: Ultra-high resolution in less time
	60°C heat decontamination This accessory, both hardware and software, enables pathogen research and comprehensive instrument service in higher biosafety-level containment facilities (e.g. BSL3) Benefit: Safe work environment for biosafety-level containment facilities
	Ceta-D Camera The Thermo Scientific Ceta-D Camera is a scintillator-based camera optimized for low-dose diffraction data collection Benefit: Perform micro electron diffraction either on a new instrument or as a retrofit onto an existing tool

Software upgrades for Thermo Scientific cryo-TEMs

Smart EPU Software

• Thermo Scientific Smart EPU Software offers a combination of interactive software components that automate multiple image acquisition steps; AI-driven technology helps you make decisions
• Benefit: Increased throughput and improved ease of use

EPU Quality Monitor

• EPU Quality Monitor Software adds real-time 2D image processing to Smart EPU Software to provide consistently better results; Smart Plugins enable automated adjustment of data collection parameters
• Benefit: Increased throughput and reproducibility

Embedded CryoSPARC Live

• Embedded CryoSPARC Live Software from Structura Biotechnology Inc. seamlessly integrates into Smart EPU Software for real-time 2D and 3D image processing; obtain ongoing feedback about both the image and the sample
• Benefit: Faster results, increased data quality, and minimized time wasted on poor quality samples

EPU Multigrid Software

• Thermo Scientific EPU Multigrid Software sets up unattended batch data collection runs
• Benefit: Maximized microscope output and user efficiency; minimized time behind the tool

Tomography 5 Software

• Thermo Scientific Tomography 5 Software offers fully automated 3D data acquisition for multi-site batch tomography and automatic cassette mapping for grid quality assessment and lamella identification
• Benefit: Maximized user efficiency by minimizing time behind the tool

Tomo Live Software

• Thermo Scientific Tomo Live Software provides automatic, on-the-fly quality monitoring of data generated with Tomography 5 Software by performing real-time reconstruction of tilt series into 3D volumes
• Benefit: Improved image quality; maximized productivity and efficiency