Real-time PCR Solutions for Pharmacogenomics | Thermo Fisher Scientific

Over seven million samples analyzed to date—and growing

Combining the power of the QuantStudio 12K Flex Real-time PCR System with qualified TaqMan genotyping assays, this solution delivers a sample-to-answer workflow that allows you to introduce pharmacogenomic testing into your laboratory with ease.

Pharmacogenomics literature

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Thermo Fisher Scientific PCR PGx research solutions: Features and benefits

Features include:

Fully qualified content—all TaqMan SNP Genotyping Assays have been tested against genomic DNA and synthetic controls
Express Panels include our most popular PGx content including—CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A5, SLCO1B1, VKORC1, COMT, OPRM1, DRD2, FII, FV, MTHFR, APOE2, APOE4
Flexible formats—our PGx solution has been optimized for anything from custom content to fit your needs, to off-the shelf content
Extensive menu of targets—over 2,700 TaqMan SNP Genotyping Assays available, targeting the most common drug metabolizing enzyme (DME) markers (including CYP2D6, CYP2C9, CYP4F2, and more)
Calling and reporting solutions—TaqMan Genotyper Software and AlleleTyper Software are available* to quickly and easily determine haplotypes of samples using star-allele nomenclature
Utilizing familiar instruments—our PGx solutions can be run on either QuantStudio 5 or QuantStudio 7 for custom plates, and QuantStudio 12K Flex System for OpenArray

*Additional PGx data and support files at bottom of page

	TaqMan OpenArray (OA)	TaqMan Array Plates (TAP)
Focus	For mid-higher throughput applications	For low-mid throughput applications
Targets	TaqMan OpenArray PGx Express – 60: 48 samples/plate 60 pre-selected TaqMan PGx Assays	32 assays x 12 samples: 80 plates 64 assays x 6 samples: 160 plates 128 assays x 3 samples: 320 plates
Goals/needs	Customers who need between 48–120 markers Genotyping of DME	Customers who need between 12–60 markers Seamless, streamlined genotyping and Copy Number Variation (CNV) in single workflow Less waste
Format	Off-the-Shelf and Custom 2,880 reactions with pre-spotted assays 4-hour workflow	Off-the-Shelf and Custom 384-well plates with pre-spotted assays PGx Express (60) on 384-well plates 3-hour workflow
Compatible instruments	QuantStudio 12K Flex Real-Time PCR System with OpenArray block	QuantStudio 12K Flex with 384-well block QuantStudio 7 Flex & 7 Pro with 384-well block QuantStudio 6 Flex & 6 Pro with 384-well block QuantStudio 5 with 384-well block

Accessories

Product	Unit Size	Catalog Number	Ordering information
TaqMan™ OpenArray™ Genotyping Master Mix	1 kit	4404846	Click to view
TaqMan™ Genotyping Master Mix	Sizes vary	Multiple SKUs	Click to view
TaqPath™ ProAmp™ Master Mix	Sizes vary	Multiple SKUs	Click to view