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Solutions for PFAS analysis
In the increasingly regulated area of environmental testing, determining the best workflow for your PFAS analysis can be challenging. Learn how our workflows meet the requirements of established regulatory methods to help you perform targeted analysis of known PFAS compounds or discover previously unknown and evolving PFAS compounds in water, soil and air.
PFAS analytical testing challenges
See how Thermo Scientific solutions can help you address your PFAS analytical testing challenges.
PFAS roadmap
Learn more about PFAS, its history, impact on public health, detection in water and soil, and strategies for reducing PFAS in the environment.
PFAS testing: technologies to meet regulatory demands
Understand key considerations to help PFAS testing labs navigate the latest regulations.
On-demand webinar: Why is PFAS testing so challenging?
Register to listen to our exclusive roundtable event where industry leaders in the field shared their experiences and discussed various topics to help PFAS analytical testing laboratories future-proof themselves in this constantly evolving area of environmental testing.
Start-to-finish PFAS analytical solutions
Whether you need just a single component to complete an analysis or everything from sample preparation to chromatography and mass spectrometry and data analysis software, we have you covered. We offer solutions for problems at any step of your analytical process, no matter the size or scope of your PFAS project.
PFAS detection in water
PFAS need to be detected in all types of water, including drinking, ground, and surface waters as well as wastewater. Whether you are performing targeted analysis to determine what types of known PFAS compounds are in your sample or conducting unknown screening to discover new and emerging PFAS in water, our accelerated solvent extraction sample preparation instruments and triple quadrupole or high-resolution accurate-mass LC-MS/MS instruments can meet your requirements.
Determination of AOF in aqueous samples using combustion IC
Access an automated method developed by scientists at Hessian State Laboratory to determine a range of PFAS compounds using automated combustion ion chromatography*.
Determination of PFAS in water using US EPA Method 537.1
Learn about a reliable, sensitive method to fulfill the requirements of US EPA Method 537.1 using a PFAS-safe sample preparation system and LC-MS/MS.
Determining PFAS in environmental waters using US EPA Method 8327
Read about a method for determining 24 PFAS compounds from ground, surface, and wastewaters using LC-MS/MS and meeting the requirements of US EPA Method 8327.
* Determination of AOF using combustion IC supports Draft US EPA Method 1621 .
PFAS detection in soil
Studies have shown that PFAS compounds have been found in soil globally and may be even more prevalent in soil than they are in water. Extracting, detecting and quantifying a wide range of PFAS chemicals from soil can pose challenges. As a result, the US EPA issued Draft Method 1633 for detecting PFAS chemicals in non-potable matrices. Thermo Scientific sample preparation, chromatography, and mass spectrometry instruments and software can provide these analyses for both targeted and unknown screening of PFAS compounds in soil.
Extraction and analysis of poly- and perfluoroalkyl substances (PFAS) from soil
Detecting and quantifying PFAS in soil is as critical as detection in water. In this application note, scientists from Pacific Rim Laboratories describe an effective method of using accelerated solvent extraction (ASE) to extract 24 PFAS compounds from soil, followed by solid-phase extraction (SPE) and LC-MS/MS analysis.
PFAS detection in air
Detecting airborne concentrations of PFAS is critical for measuring emission distribution and potential risk of human exposure. Unlike PFAS in water and soil matrices, PFAS in air can travel thousands of kilometers from the original point of emission and can contribute significantly to air pollution. The US EPA is working to better regulate air emissions of PFAS and Thermo Scientific chromatography instruments can help navigate the evolving regulatory landscape.
High-throughput analysis of neutral and ionic PFAS in ambient air
One of the main challenges of analyzing air samples for PFAS is that the compounds occur in trace concentrations in air, so low detection limits are crucial. This application note provides an in-depth overview of a high-throughput method for simultaneous analysis of PFAS in air using thermal desorption coupled to gas chromatography.
For additional resources on air quality analysis products and compliance guidelines, visit our Air Quality Analysis Learning Center hub.
PFAS toolkit
Perfluoroalkyl substances, or PFAS, are contaminants of increasing concern. We have the products and applications experience to help you achieve optimal analysis for PFAS compounds.
What do I need for PFAS analysis?
The best instruments and workflows for your PFAS analysis depend on the sample you need to analyze and whether it requires targeted analysis or unknown screening. The sections below offer guidance about which sample preparation and analytical systems are right for different sample types and workflows.
Sample preparation solutions
Whether you are analyzing water or soil samples and require either automated or manual sample preparation, we have the right product for you.
| Solid phase extraction cartridges & plates | Accelerated solvent extraction | Automated solid-phase extraction | TriPlus RSH EQuan 850 System | |
|---|---|---|---|---|
 |  |  |  | |
| Automated | – | |||
| Soil samples | – | |||
| Water samples | – |
Learn more about our sample preparation products for chromatography.
Analytical systems for PFAS analysis
We offer chromatography, mass spectrometry and software for all types of PFAS determinations, including targeted and untargeted screening and quantitation, retrospective analysis and screening for unknown PFAS compounds.
| Combustion IC system | Triple quadrupole LC-MS | Orbitrap Exploris 120 HRAM LC-MS | |
|---|---|---|---|
 |  |  | |
| Untargeted screening | – | – | |
| Targeted screening | Analysis of organofluorines | ||
| Untargeted and targeted quantitation | – | ||
| Retrospective analysis | – | ||
| Analysis of unknowns (TraceFinder software) | – | – |
Learn more about our LC-MS systems ›
Learn more about combustion IC ›
PFAS data processing solutions - with the right software, forever chemicals do not need forever analysis
We hear you - analyzing PFAS compounds in environmental matrices, especially via untargeted analysis, is a major challenge. Read this smart note to understand the critical considerations that can help ensure your testing laboratory is meeting the evolving requirements for PFAS data analysis.
Videos and webinars about PFAS detection
View our collection of educational, on-demand webinars to give you a deeper understanding of PFAS testing. Alternatively, watch one of our informational videos to hear how Thermo Fisher Scientific is making it easier to perform analyses of PFAS compounds in environmental samples.
Webinar: Analysis of PFAS compounds in drinking water
Webinar: Determination of unknown PFAS compounds
Virtual workshop: Analysis of PFAS with combustion IC**
** Methods discussed in this workshop support Draft US EPA Method 1621 .
Connect with us
When it comes to advancing your analytical capabilities, learning from other experts is key. Get regular updates on new instrumentation and methods for environmental analysis from Thermo Fisher Scientific and join our community to connect with our expert and your colleagues around the globe.
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