| Application | Title | Source | Year |
|---|
| stem cells | A head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10) | European Journal of Pharm Biopharm | 2020 |
| cancer, neuroscience | A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules | Scientific Reports | 2020 |
| cancer, virology | Advanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystems | Scientific Reports | 2020 |
| stem cells | Aryl hydrocarbon receptor modulation by tuberculosis drugs impairs host defense and treatment outcomes | Cell Host & Microbe | 2020 |
| neuroscience | Benzalkonium chloride-induced direct and indirect toxicity on corneal epithelial and trigeminal neuronal cells: proinflammatory and apoptotic responses in vitro | Toxicology letters | 2020 |
| | Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection | Am J Perinatol | 2020 |
| cancer, neuroscience, stem cells, organoids | Constitutive Activity of a G Protein‐Coupled Receptor, DRD1, Contributes to Human Cerebral Organoid Formation | STEM CELLS | 2020 |
| cancer, neuroscience | Cyclin-dependent kinase 18 controls trafficking of aquaporin-2 and its abundance through ubiquitin ligase STUB1, which functions as an AKAP | Cells | 2020 |
| cancer, neuroscience, stem cells | Detection of Rare Objects by Flow Cytometry: Imaging, Cell Sorting, and Deep Learning Approaches | Intl J Mol Science | 2020 |
| cancer, neuroscience | Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent … | Cancer Biol Med | 2020 |
| cancer, immunotherapy, neuroscience | Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics | Med Res Rev | 2020 |
| | Identification and analyses of inhibitors targeting apolipoprotein (a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function | Journal of Biological Chemistry | 2020 |
| stem cells | In vivo expansion of functional human hematopoietic stem progenitor cells by butyzamide | International Journal of Hematology | 2020 |
| cancer, neuroscience | Knockdown of HSDL2 inhibits lung adenocarcinoma progression via down-regulating AKT2 expression | Bioscience Reports | 2020 |
| cancer, immunotherapy, neuroscience | Kushenol E inhibits autophagy and impairs lysosomal positioning via VCP/p97 inhibition | Biochemical Pharmacol | 2020 |
| cancer, neuroscience | Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic … | European Journal of Med Chem | 2020 |
| virology | Magnitude and diversity of immune response to vaccinia virus is dependent on route of administration | Virology | 2020 |
| | miR-182-3p/Myadm contribute to pulmonary artery hypertension vascular remodeling via a KLF4/p21-dependent mechanism | Theranostics | 2020 |
| cancer, neuroscience | Nuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanism | Communications Biology | 2020 |
| neuroscience | Specific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated Neurotoxicity | Cell Chemical | 2020 |
| stem cells | thalidomide inhibits Human ipSc Mesendoderm Differentiation by Modulating cRBn-dependent Degradation of SALL4 | Scientific Reports | 2020 |
| stem cells | Suppression of adipocyte differentiation by low‐intensity pulsed ultrasound via inhibition of insulin signaling and promotion of CCN family protein 2 | Journal of Cellular Biochem | 2020 |
| | Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells | Toxicology Reports | 2020 |
| | The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5 | Journal of Biological Chemistry | 2020 |
| cancer | YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling | Journal of Transl Med | 2020 |
| cancer | A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest | Nucleic Acids Res | 2019 |
| cancer, neuroscience | UBQLN4 represses homologous recombination and is overexpressed in aggressive tumors | Cell | 2019 |
| neuroscience | Unconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neurons | Scientific Reports | 2019 |
| cancer, neuroscience | Vitegnoside Mitigates Neuronal Injury, Mitochondrial Apoptosis, and Inflammation in an Alzheimer's Disease Cell Model via the p38 MAPK/JNK Pathway | Journal of Alzheimer's Dis | 2019 |
| neuroscience | Triclosan Affects Ca2+ Regulatory Module and Musculature Development in Skeletal Myocyte during Early Life Stages of Zebrafish (Danio rerio) | Environmental Science & Technology | 2019 |
| cancer | Exploration of the chondrosarcoma metabolome; the mTOR pathway as an important pro-survival pathway | J Bone Oncol | 2019 |
| cancer | Wee1 inhibitor AZD1775 effectively inhibits the malignant phenotypes of esophageal squamous cell carcinoma in vitro and in vivo | Frontiers in Pharmacol | 2019 |
| cancer, stem cells | YES1 is a targetable oncogene in cancers harboring YES1 gene amplification | Cancer Research | 2019 |
| | A high content screening assay for identifying inhibitors against active and dormant state intracellular Mycobacterium tuberculosis | Journal of Microbiological Methods | 2019 |
| cancer, stem cells | A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation | Oncotarget | 2019 |
| cancer, neuroscience, stem cells, organoids | A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model | Stem Cells and Dev | 2019 |
| cancer, immunotherapy, stem cells | Advanced Materials and Devices for the Regulation and Study of NK Cells | International Journal of Molecular Sciences | 2019 |
| cancer | AMMECR1 Inhibits Apoptosis and Promotes Cell-cycle Progression and Proliferation of the A549 Human Lung Cancer Cell Line | Anticancer Res | 2019 |
| neuroscience, stem cells | An analog derived from phenylpropanoids ameliorates Alzheimer's disease–like pathology and protects mitochondrial function | Neurobiology of Aging | 2019 |
| | Analysis and quantification of oxidized low-density lipoprotein-induced lipid droplets in macrophages through high-content screening: Application for antiatherogenic … | Assay and Drug Development Technologies | 2019 |
| | Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1–Nrf2–Are signaling pathway | J Cell Physiol | 2019 |
| cancer | Anlotinib inhibits synovial sarcoma by targeting GINS1: a novel downstream target oncogene in progression of synovial sarcoma | Clinical and Translational Oncology | 2019 |
| cancer, immunotherapy, neuroscience | Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes | Scientific Reports | 2019 |
| cancer | ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure | Genetic Med | 2019 |
| cancer, stem cells | Arrayed functional genetic screenings in pluripotency reprogramming and differentiation | Stem Cell Research & Therapy | 2019 |
| cancer, immunotherapy | Anticancer Activity of Earthworm Powder (Lumbricus terrestris) Against MCF-7 and PC-3 Cancer Cell Lines | Journal of Gastrointestinal Cancer | 2019 |
| cancer | Automated Detection of Autophagy Response Using Single Cell-Based Microscopy Assays | Autophagy | 2019 |
| neuroscience | Blue light exposure in vitro causes toxicity to trigeminal neurons and glia through increased superoxide and hydrogen peroxide generation | Free Radic Biol Med | 2019 |
| cancer, stem cells | Cardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes | Toxicol Sci | 2019 |
| stem cells | Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation | Nature | 2019 |
| cancer | MAT2B expression correlates with poor prognosis in triple-negative breast cancer | Cancer Management and Research | 2019 |
| cancer, stem cells, organoids | MDH1 and MPP7 regulate autophagy in pancreatic ductal adenocarcinoma | Cancer Research | 2019 |
| cancer, stem cells | Extracellular vesicles induce minimal hepatotoxicity and immunogenicity | Nanoscale | 2019 |
| cancer | Functional characterization of glucocorticoid receptor variants is required to avoid misinterpretation of NGS data | J Endocr Soc | 2019 |
| cancer | Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders | Genes | 2019 |
| cancer, immunotherapy | Casein Kinase 2 Interacting Protein-1 Suppresses Glioma Cell Proliferation via Regulating the AKT/GSK3/-Catenin Pathway | Biomed Res Int | 2019 |
| cancer, neuroscience | High content screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensate | Toxicology in Vitro | 2019 |
| | Differentiated mitochondrial function in mouse 3T3 fibroblasts and human epithelial or endothelial cells in response to chemical exposure | Basic Clin Pharmacol Toxicol | 2019 |
| virology | Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis | Scientific reports | 2019 |
| cancer | Differentiation of Aneugens and Clastogens in the In Vitro Micronucleus Test by Kinetochore Scoring Using Automated Image Analysis | Environ Mol Mutagen | 2019 |
| stem cells | Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis | Nat Commun | 2019 |
| neuroscience | Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α 2 δ-1 with thrombospondin-4 | Scientific Reports | 2019 |
| cancer | Functional regulation of human trophoblast cells by CSE1L | J Matern Fetal Neonatal Med | 2019 |
| | Fuzhenghuayu Decoction ameliorates hepatic fibrosis by attenuating experimental sinusoidal capillarization and liver angiogenesis | Scientific Reports | 2019 |
| cancer, neuroscience | MTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury Responses | Scientific Reports | 2019 |
| cancer, neuroscience, stem cells | Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension | J Pathology | 2019 |
| cancer, neuroscience | High glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cells | Cell Metabolism | 2019 |
| cancer, neuroscience | High-Content Imaging of Immunofluorescently Labeled TRPV1-Positive Sensory Neurons | Method Mol Bio | 2019 |
| stem cells, organoids | High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets | Journal of Molecular and Cell Cardiol | 2019 |
| neuroscience, stem cells | High‐throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell culture | Biotechnology and Bioeng | 2019 |
| cancer, immunotherapy, stem cells | B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells | Oncogene | 2019 |
| cancer, neuroscience | Downregulation of CPA4 inhibits non small–cell lung cancer growth by suppressing the AKT/c‐MYC pathway | Mol Carcinogen | 2019 |
| cancer | Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen | Autophagy | 2019 |
| cancer | Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma | PNAS | 2019 |
| neuroscience, stem cells | Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons | Eur J Med Chem | 2019 |
| cancer, stem cells | NaCl nanoparticles as a cancer therapeutic | Advanced Materials | 2019 |
| | Ptr/CTL0175 is required for the efficient recovery of Chlamydia trachomatis from stress induced by gamma-interferon | Frontiers in Microbiology | 2019 |
| cancer | Pu-erh tea relaxes the thoracic aorta of rats by reducing intracellular calcium | Front Pharmacol | 2019 |
| | Quercetin protect cigarette smoke extracts induced inflammation and apoptosis in RPE cells | Artif Cells Nanomed Biotechnol | 2019 |
| cancer | Knockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cell | Journal of Cellular Biochem | 2019 |
| cancer, virology | Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide | eLife | 2019 |
| cancer | Glutathione accelerates osteoclast differentiation and inflammatory bone destruction | Free Radical Res | 2019 |
| cancer, stem cells | Glycylglycine plays critical roles in the proliferation of spermatogonial stem cells | Molecular Med Rep | 2019 |
| neuroscience | GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis | Cell | 2019 |
| | Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibiotics | Toxicology in Vitro | 2019 |
| cancer, neuroscience | Cell‐based high‐throughput screen for small molecule inhibitors of Bax translocation | J Cell Mol Med | 2019 |
| cancer, virology | Lentivirus mediated γ-interferon-inducible lysosomal thiol reductase (GILT) knockdown suppresses human glioma U373MG cell proliferation | Biochem Biophys Res Commun | 2019 |
| cancer | LIMD 1 phosphorylation in mitosis is required for mitotic progression and its tumor‐suppressing activity | FEBS | 2019 |
| cancer, stem cells | In-depth proteome analysis highlights HepaRG cells as a versatile cell system surrogate for primary human hepatocytes | Cells | 2019 |
| cancer, stem cells | KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone | Oncogene | 2019 |
| cancer | Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins | Nephron | 2019 |
| cancer | Stable Redox-Cycling Nitroxide Tempol Has Antifungal and Immune-Modulatory Properties | Frontiers in Microbiology | 2019 |
| cancer | Staphylococcus aureus induces DNA damage in host cell | Scientific Reports | 2019 |
| cancer, neuroscience | Structural analysis and cellular visualization of APP RNA G-quadruplex | Chemical Science | 2019 |
| cancer | Synthesis and evaluation of 1, 3, 4-oxadiazole derivatives for development as broad-spectrum antibiotics | Bioorganic & Medicinal Chem | 2019 |
| cancer, neuroscience | Synthetic probe development for measuring single or few-cell activity and efflux | Methods in Enzymology | 2019 |
| cancer | The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418 | PloS One | 2019 |
| cancer | The tetrahydroxanthone-dimer phomoxanthone A is a strong inducer of apoptosis in cisplatin-resistant solid cancer cells | Bioorganic & Medicinal Chemistry | 2019 |
| neuroscience, stem cells | Tilianin mediates neuroprotection against ischemic injury by attenuating CaMKII-dependent mitochondrion-mediated apoptosis and MAPK/NF-κB signaling | Life Sciences | 2019 |
| cancer | Knockdown expression of MECR, a novel gene of mitochondrial FAS II inhibits growth and colony-formation, promotes apoptosis of hepatocellular carcinoma cells | Bioscience Trends | 2019 |
| cancer, neuroscience | Induction of migration of periodontal ligament cells by selective regulation of integrin subunits | Journal of Cellular Mol Med | 2019 |
| cancer | BAI1‑associated protein 2‑like 2 is a potential biomarker in lung cancer | Oncology Report | 2019 |
| cancer, neuroscience | miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3–Binding Domain to Regulate Wnt1 | Molecular Cancer Res | 2019 |
| cancer | Chlamydia trachomatis fails to protect its growth niche against pro-apoptotic insults | Cell Death Differ | 2019 |
| cancer, immunotherapy | CIZ1 knockdown suppresses the proliferation of bladder cancer cells by inducing apoptosis | Gene | 2019 |
| cancer, immunotherapy, stem cells, virology | Development of a novel screening platform for the identification of small molecule inhibitors of human adenovirus | Virology | 2019 |
| neuroscience, stem cells | Transcriptomically Guided Mesendoderm Induction of Human Pluripotent Stem Cells Using a Systematically Defined Culture Scheme | Stem Cell Reports | 2019 |
| cancer | Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability | Molecular cell | 2019 |
| virology | Endophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cells | Emerging microbes & … | 2019 |
| cancer, neuroscience, stem cells | Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs | Neuroscience Bull | 2019 |
| | Nanoscale coupling of endocytic pit growth and stability | Science Adv | 2019 |
| cancer, neuroscience | NHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cells | Clinical & Experimental Metastasis | 2019 |
| cancer | Combined PPARγ activation and XIAP inhibition as a potential therapeutic strategy for ovarian granulosa cell tumors | Mol Cancer Therap | 2019 |
| | Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modifications | High-throughput | 2019 |
| | Interaction of mycobacteria with Plasmin (ogen) affects phagocytosis and granuloma development | Tuberculosis | 2019 |
| neuroscience, virology | Interferon-induced transmembrane protein 1 restricts replication of viruses that enter cells via the plasma membrane | Journal of Virology | 2019 |
| cancer, neuroscience, stem cells | Cytotoxic Mechanism for Silver Nanoparticles Based High-Content Cellomics and Transcriptome Sequencing | J Biomed Nanotechnol | 2019 |
| | Anti-inflammatory activity of dehydroandrographolide by TLR4/NF-κB signaling pathway inhibition in bile duct-ligated mice | Cell Physiol Biochem | 2018 |
| cancer, stem cells | An endothelial cell/mesenchymal stem cell coculture cord formation assay to model vascular biology in vitro | Methods Mol Biol | 2018 |
| cancer, neuroscience | Anti-inflammatory effects and mechanism of the total flavonoids from Artemisia scoparia Waldst. et kit. in vitro and in vivo | Biomed Pharmacother | 2018 |
| cancer | Assessment of novel tobacco heating product THP1. 0. Part 6: a comparative in vitro study using contemporary screening approaches | Regul Toxicol Pharmacol | 2018 |
| cancer, neuroscience, stem cells | BCL2 and BCL (X) L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2 … | Oncotarget | 2018 |
| cancer, neuroscience | Bioinspired Honokiol Analogs and Their Evaluation for Activity on the Norepinephrine Transporter | Molecules | 2018 |
| cancer, stem cells | Cell-Based High Content Analysis of Cell Proliferation and Apoptosis | High Content Screening | 2018 |
| cancer | Cellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatment | Int J Biochem Cell Biol | 2018 |
| cancer | Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion | Autophagy | 2018 |
| cancer, stem cells, virology | Compounds producing an effective combinatorial regimen for disruption of HIV‐1 latency | EMBO Mol Med | 2018 |
| cancer | Conjugate Polyplexes with Anti-Invasive Properties and Improved siRNA Delivery In Vivo | Bioconjugate Chemistry | 2018 |
| cancer, neuroscience | CoQ10 ameliorates mitochondrial dysfunction in diabetic nephropathy through mitophagy | J Endocrinol | |
| cancer | Cyclodextrin-and dendrimer-conjugated graphene oxide as a nanocarrier for the delivery of selected chemotherapeutic and photosensitizing agents | Mater Sci Eng C Mater Biol Appl | 2018 |
| cancer | Delivery of miR-146a to Ly6Chigh monocytes inhibits pathogenic bone erosion in inflammatory arthritis | Theranostics | 2018 |
| cancer | Development and application of high-content biological screening for modulators of NET production | Frontiers in Immunol | 2018 |
| neuroscience | Development of a cell-based assay to assess binding of the proNGF prodomain to sortilin | Cell Mol Neuro | 2018 |
| cancer | Diazinon exposure activated transcriptional factors CCAAT-enhancer-binding proteins α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ) and … | Pesticide Biochemistry and Physiology | 2018 |
| cancer | Discovery of the first potent, selective, and orally bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) inhibitor displaying pronounced immunomodulatory effects … | J Med Chem | 2018 |
| cancer | Discovery of the Polyamine Conjugate with Benzo[cd]indol-2(1H)-one as a Lysosome-Targeted Antimetastatic Agent | J Med Chem | 2018 |
| cancer | Downregulation of RNA binding motif protein 17 expression inhibits proliferation of hypopharyngeal carcinoma FaDu cells | Oncology | 2018 |
| cancer, neuroscience, stem cells, organoids | DYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor Cells | Stem Cells Dev | 2018 |
| | Elevated transforming growth factor β signaling activation in β‐actin‐knockout mouse embryonic fibroblasts enhances myofibroblast features | Journal of cellular physiology | 2018 |
| cancer | Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes | Free Radic Biol Med | 2018 |
| | Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment | Scientific reports | 2018 |
| cancer, immunotherapy | Extracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapy | J Surg Res | 2018 |
| virology | Functional insights into the adjacent stem-loop in honey bee dicistroviruses that promotes internal ribosome entry site-mediated translation and viral infection | Journal of virology | 2018 |
| neuroscience, stem cells | FZD4 marks lateral plate mesoderm and signals with NORRIN to increase cardiomyocyte induction from pluripotent stem cell-derived cardiac progenitors | Stem Cell Reports | 2018 |
| cancer, neuroscience, stem cells | Genes and pathways regulated by androgens in human neural cells, potential candidates for the male excess in autism spectrum disorder | Biol Psychiatry | 2018 |
| cancer, stem cells | Genetic and chemical screenings identify HDAC3 as a key regulator in hepatic differentiation of human pluripotent stem cells | Stem Cell Reports | 2018 |
| cancer | High content imaging assays for IL-6-induced STAT3 pathway activation in head and neck cancer cell lines | Method Mol Bio | 2018 |
| cancer, virology | High content positional biosensor assay to screen for compounds that prevent or disrupt androgen receptor and transcription intermediary factor 2 protein-protein … | Method Mol Bio | 2018 |
| cancer, stem cells | High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma | PloS One | 2018 |
| cancer, neuroscience, stem cells | Host-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiota | Nat Commun | 2018 |
| cancer, immunotherapy, neuroscience | Human corticotrophin releasing factor inhibits cell proliferation and promotes apoptosis through upregulation of tumor protein p53 in human glioma | Oncology Letters | 2018 |
| cancer, neuroscience, stem cells | Human-derived neurons and neural progenitor cells in high content imaging applications | Method Mol Bio | 2018 |
| cancer, neuroscience, virology | Identification of Hsp90 inhibitors with anti-Plasmodium activity | Antimicrobial Agents Chemotherapy | 2018 |
| cancer, neuroscience | Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death | Neurobiology of Disease | 2018 |
| cancer, stem cells | Inhibition of human prostate cancer (PC-3) cells and targeting of PC-3-derived prostate cancer stem cells with koenimbin, a natural dietary compound from … | Drug Design Devel Ther | 2018 |
| neuroscience | Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex | J Cell Sci | 2018 |
| cancer, neuroscience | Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis | Cell Death Discovery | 2018 |
| virology | Integrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivity | Cell Host & Microbe | 2018 |
| cancer | KIAA0101 inhibition suppresses cell proliferation and cell cycle progression by promoting the interaction between p53 and Sp1 in breast cancer | Biochemical and Biophysical Research | 2018 |
| cancer | Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis | OncoTargets and Ther | 2018 |
| cancer, stem cells | Knockdown of ubiquitin associated protein 2-like (UBAP2L) inhibits growth and metastasis of hepatocellular carcinoma | Medical Science Monitor | 2018 |
| cancer, neuroscience, stem cells | Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters | Scientific Reports | 2018 |
| cancer, neuroscience, virology | LINE-1 protein localization and functional dynamics during the cell cycle | Elife | 2018 |
| | Live-cell measurements of kinase activity in single cells using translocation reporters | Nature Protocols | 2018 |
| cancer | MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy | Nature Comms | 2018 |
| cancer, stem cells | Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines | Archives of Tox | 2018 |
| cancer, stem cells | miR-122 release in exosomes precedes overt tolvaptan-induced necrosis in a primary human hepatocyte micropatterned coculture model | Toxicological Sci | 2018 |
| cancer, stem cells | miR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma | The FASEB Journal | 2018 |
| cancer, neuroscience | Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis | Cell Death & Disease | 2018 |
| cancer | Monosomy 18p is a risk factor for facioscapulohumeral dystrophy | Journal of Medical Genetics | 2018 |
| cancer | Muscarinic acetylcholine type 1 receptor activity constrains neurite outgrowth by inhibiting microtubule polymerization and mitochondrial trafficking in adult … | Frontiers in Neuroscience | 2018 |
| cancer, neuroscience | Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons | Neuropharmacology | 2018 |
| cancer, neuroscience | N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression | Scientific Reports | 2018 |
| cancer, neuroscience, stem cells | Novel 3D liquid cell culture method for anchorage-independent cell growth, cell imaging and automated drug screening | Scientific Reports | 2018 |
| cancer | Panduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathway | Phytomedicine | 2018 |
| cancer, neuroscience, stem cells | Per-and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived model | Systems Biology in Reprod Med | 2018 |
| cancer, neuroscience, stem cells | Phenotypic and functional characteristics of human Schwann cells as revealed by cell-based assays and RNA-seq | Molecular Neurobiology | 2018 |
| cancer | Plagioneurin B, a potent isolated compound induces apoptotic signalling pathways and cell cycle arrest in ovarian cancer cells | Apoptosis | 2018 |
| cancer, neuroscience, stem cells | PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia | Science Translational Med | 2018 |
| cancer, neuroscience | Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer | Oncotarget | 2018 |
| cancer | Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy | Journal of Biological Chemistry | 2018 |
| cancer, neuroscience, stem cells | Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice | Human Molecular Genetics | 2018 |
| cancer | RBM17 controls apoptosis and proliferation to promote Glioma progression | Biochem Biophys Res Commun | 2018 |
| cancer, neuroscience | Real-time monitoring of DNA G-quadruplexes in living cells with a small-molecule fluorescent probe | Nucleic Acids Research | 2018 |
| cancer, neuroscience, stem cells, organoids | Recent Advances in Microfluidic Techniques for Systems Biology | Analytical Chemistry | 2018 |
| cancer, neuroscience, stem cells | Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination | Cell Reports | 2018 |
| cancer, neuroscience | Reversine inhibits colon carcinoma cell migration by targeting JNK1 | Scientific Reports | 2018 |
| neuroscience | A Novel RNA editing sensor tool and a specific agonist determine neuronal protein expression of RNA-edited glycine receptors and identify a genomic … | Frontiers in Molecular Neuro | 2018 |
| cancer | Role of miR‑449b‑3p in endometriosis via effects on endometrial stromal cell proliferation and angiogenesis | Molecular Medicine Reports | 2018 |
| cancer, neuroscience | RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability | Nature Cell Biology | 2019 |
| cancer, neuroscience | Severe PATCHED1 deficiency in cancer-prone Gorlin patient cells results in intrinsic radiosensitivity | Int J Radiat Oncol Biol Phys | 2018 |
| cancer, neuroscience | Soluble laminin polymers enhance axon growth of primary neurons in vitro | Journal of Biomedical Chemistry | 2018 |
| cancer | Suppression of CCT3 inhibits malignant proliferation of human papillary thyroid carcinoma cell | Oncology Letters | 2018 |
| neuroscience, stem cells, organoids | Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment | Toxicology and Applied Pharmcol | 2018 |
| cancer | TFIIA transcriptional activity is controlled by a 'cleave-and-run'Exportin-1/Taspase 1-switch | Journal of Molecular Cell Bio | 2018 |
| cancer | TGFβ promotes genomic instability after loss of RUNX3 | Cancer Research | 2018 |
| cancer, neuroscience, stem cells | The AMPK/p27Kip1 axis regulates autophagy/apoptosis decisions in aged skeletal muscle stem cells | Stem Cell Reports | 2018 |
| cancer, neuroscience | The biological effects of long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product | Toxicology in Vitro | 2018 |
| cancer, stem cells | The Cdkn1aSUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression | Cell Reports | 2018 |
| cancer, neuroscience, stem cells | The dynamics of TGF-β signaling are dictated by receptor trafficking via the ESCRT machinery | Cell Reports | 2018 |
| cancer, neuroscience | The effect of Jun dimerization on neurite outgrowth and motif binding | Molecular and Cellular Neuroscience | 2018 |
| cancer | The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma | Oncogene | 2018 |
| cancer | The lead optimization of the polyamine conjugate of flavonoid with a naphthalene motif: Synthesis and biological evaluation | European Journal of Med Chem | 2018 |
| cancer, neuroscience | The relative composition of actin isoforms regulates cell surface biophysical features and cellular behaviors | Biochimica et Biophysica | 2018 |
| cancer, neuroscience, stem cells | Tools to measure cell health and cytotoxicity using high content imaging and analysis | Methods Mol Biol | 2018 |
| virology | Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells | Scientific Reports | 2018 |
| cancer | UBE2S promotes the proliferation and survival of human lung adenocarcinoma cells | BMB reports | 2018 |
| cancer, neuroscience, stem cells | β-Actin–dependent global chromatin organization and gene expression programs control cellular identity | The FASEB Journal | 2018 |
| cancer, neuroscience, stem cells, organoids, virology | A fluorescent cell-based system for imaging Zika virus infection in real-time | Viruses | 2018 |
| cancer, neuroscience | A stress-enhanced model for discovery of disease-modifying gene: Ece1-suppresses the toxicity of α-synuclein A30P | Neurobiology of Disease | 2018 |
| cancer, stem cells | A β1-tubulin–based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production | Blood Adv | 2018 |
| cancer, neuroscience | Activation of Nrf2 signaling by salvianolic acid C attenuates NF‑κB mediated inflammatory response both in vivo and in vitro | Int Immunopharmacol | 2018 |
