Learn how the Vanquish Neo UHPLC system can bring value to your lab.

Discover why the Vanquish Neo UHPLC system is the new standard in low-flow LC.

Learn how the Vanquish Neo UHPLC system accelerates new discoveries and productivity.

All-in-one low-flow UHPLC system

  • ProFlow XR technology delivers excellent retention time precision from nano up to 100 μL/min at pressures up to 1500 bar
  • Industry-leading flow-pressure footprint enables high-resolution separations on ultra-long columns and high throughput

 Learn more

Maximum performance

  • Next-generation SmartInject technology drives retention time precision, column lifetime, and ESI stability
  • Automated multi-wash procedures improve low-level analyte sensitivity
  • Vial bottom detection enables precise and accurate injections with minimal sample waste

 Learn more

Enhanced productivity

  • Fast sample loading and column equilibration improves sample throughput and MS utilization
  • Unique split-loop autosampler design minimizes sample dispersion and sample waste while enhancing workflow versatility
  • The tandem direct injection workflow provides maximized sample throughput and mass spectrometer utilization

 Learn more

Versatile LC-MS workflows

  • Seamless integration with the Thermo Scientific mass spectrometry portfolio through a comprehensive suite of ESI sources
  • Optimized configurations including direct and tandem direct injection, and trap-and-elute workflows ensure superior performance and system versatility

 Learn more

Intelligent operation

  • The Vanquish User Interface improves your user experience by providing walk-up and remote system monitoring, control, and automated procedures
  • The method editor wizard ensures compatibility of method parameters with installed consumables

 Learn more

All-in-one low-flow UHPLC system

  • ProFlow XR technology delivers excellent retention time precision from nano up to 100 μL/min at pressures up to 1500 bar
  • Industry-leading flow-pressure footprint enables high-resolution separations on ultra-long columns and high throughput

 Learn more

Maximum performance

  • Next-generation SmartInject technology drives retention time precision, column lifetime, and ESI stability
  • Automated multi-wash procedures improve low-level analyte sensitivity
  • Vial bottom detection enables precise and accurate injections with minimal sample waste

 Learn more

Enhanced productivity

  • Fast sample loading and column equilibration improves sample throughput and MS utilization
  • Unique split-loop autosampler design minimizes sample dispersion and sample waste while enhancing workflow versatility
  • The tandem direct injection workflow provides maximized sample throughput and mass spectrometer utilization

 Learn more

Versatile LC-MS workflows

  • Seamless integration with the Thermo Scientific mass spectrometry portfolio through a comprehensive suite of ESI sources
  • Optimized configurations including direct and tandem direct injection, and trap-and-elute workflows ensure superior performance and system versatility

 Learn more

Intelligent operation

  • The Vanquish User Interface improves your user experience by providing walk-up and remote system monitoring, control, and automated procedures
  • The method editor wizard ensures compatibility of method parameters with installed consumables

 Learn more

Drive your science forward by incorporating the Vanquish Neo UHPLC system into a workflow with other Thermo Scientific products, including our low-flow (U)HPLC columns, industry-leading mass spectrometers, and a software platform that streamlines your laboratory processes.

Thermo Scientific Orbitrap Astral mass spectrometer

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Thermo Scientific Stellar
mass spectrometer

The Thermo Scientific Stellar Mass Spectrometer offers a combination of robust quantitation and the specificity of rapid full scan MSn acquisition.

Style Sheet for Global Design System
Style Sheet for Komodo Tabs
CMD Wide-format style fixes