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Vanquish Horizon UHPLC System
The Thermo Scientific Vanquish Horizon UHPLC system provides unrivaled performance and throughput for applications requiring high-end UHPLC, ideal for research and development labs. With a fully biocompatible flowpath and ultra-low gradient delay volume, it offers superior separations with unsurpassed retention time and peak area precision, excellent detector sensitivity and lower baseline noise for the most demanding LC and LC-MS workflows. Like all members of our Vanquish product line, Vanquish Horizon UHPLC systems offer hardware precision, detector sensitivity, and simplicity of operation.
Highlights
Powerful separations
Vanquish Binary Pump H delivers industry-leading UHPLC flow performance using SmartFlow, SmartStroke and Adaptive Thermal Effect Compensation (ATEC) technologies at maximum operating pressures of up to 1500 bar (22,000 psi).
Mastering most challenging LC-MS applications
Industry-leading performance results in the highest retention time stability, chromatographic resolution and selectivity. This supports LC-MS workflows using ultra-fast gradients and produces the highest quality data with respect to precision, accuracy and reproducibility.
Automated sample handling
Vanquish Split Sampler HT offers outstanding speed and injection precision using SmartInject technology. It has a default vial capacity of 216 samples, which can be extended up to 8832 samples with the Vanquish Charger sampler extension.
Sensitive analyte detection
The Vanquish Diode Array Detector HL includes LightPipe technology, featuring a long light path with low dispersion for fast and sensitive detection. We offer additional detection options, including near-universal charged aerosol detection, fluorescence detection and mass spectrometric detection.
Biocompatible, easy and reliable tool-free connections
The fluidic pathway of the Vanquish Horizon UHPLC system is fully biocompatible and fitted with Thermo Scientific Viper fingertight fittings, which support near-zero dead volume connections and enable sharper peaks and tool-free setup.
CDS software
The Vanquish Horizon UHPLC system integrates with Thermo Scientific Chromeleon Chromatography Data System (CDS) with compliance tools, networking capabilities, automation, and data processing. We offer standard instrument integration (SII) packages to connect Thermo Scientific HPLC systems to other CDS and MS software programs.
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System specifications
The table below provides an overview of the Vanquish Horizon UHPLC system specifications for a standard setup. Not all specifications are listed. Your specifications may differ based on the components of your system. Find the specification sheets for the system components in the Component specifications, below.
| Category | Vanquish Horizon UHPLC System |
| System pressure, maximum | 1500 bar |
| Flow range | 0–5 mL/min |
| Pump options (default gradient delay volume) | Binary (35 µL) |
| Biocompatible | Yes |
| pH range | 2–12, chloride concentration up to 1 mol/L |
| System design | Modular |
| Touchscreen user interface display compatible (optional) | No |
| Solvent monitoring system compatible (optional) | Yes |
| Customizable gradient delay volume to simplify method transfer | Yes, with metering device |
SmartInject technology for maximum injection precision and improved column lifetime |
Yes |
| Injection volume range | Standard: 0.01-25 µL Optional: 0.01-100 µL |
| Sample cooling | Yes, 4-40°C |
| Sample capacity (standard) Based on standard 12 mm OD vials (≤ 1.5 mL) |
4 racks of 54 vials (≤ 1.5 mL) each, other rack formats available + capacity of 12 × 22.5 mm OD vials (≤ 10 mL) in the carousel |
| Sampler extension available | Yes, with Vanquish Charger |
| Column compartment thermostatting | Yes, 5-120 °C Still air and forced air |
| Column compartment pre-heater | Active and passive |
| Column compartment post-column cooler | Yes |
| Detector choices | Vanquish Charged Aerosol Detector Vanquish Diode Array Detector Vanquish Fluorescence Detector Vanquish Multiple Wavelength Detector Vanquish Variable Wavelength Detector Mass Spectrometer |
Component specifications
Standard Vanquish Horizon UHPLC systems are made up of the following components. Talk to your local sales rep to discuss your application needs. Download the associated specifications sheet for more detail on each component.
| Vanquish Horizon UHPLC | |
Pump
|
Vanquish Binary Pump H |
Autosampler
|
Vanquish Split Sampler HT |
Extended sample capacity (optional)
|
Vanquish Charger (optional) |
Column compartment
|
Vanquish Column Compartment H |
Virtually zero dead volume system connections
|
Viper UHPLC Fittings Kits |
Detectors
|
Visit our HPLC and UHPLC Detectors page |
| Optional components: Fraction Collector | Visit our Vanquish Fraction Collector FT page |
For Research Use Only. Not for use in diagnostic procedures.