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Spindle microtubules labeled with an anti-tubulin primary antibody followed by (left) goat anti–mouse IgG antibody colloidal gold or (right) NANOGOLD Fab' fragment of goat anti–mouse IgG antibody (Cat. no. N24915). Micrographs (magnification = 1300x) were generated by D. Vandre and R. Burry, Ohio State University. Image courtesy of Nanoprobes, Inc.