An All-In-One Process Raman Solution

An all-in-one process Raman solution 

The Thermo Scientific MarqMetrix All-In-One Process Raman Analyzer enables real-time, accurate spectral results for in-line, at-line, or on-line process monitoring. The MarqMetrix All-In-One Process Raman Analyzer redesigns how Process Raman Spectroscopy adds value to the Process Analytical Technology (PAT) workflow by focusing on a customized and user-centric experience through its rapid setup, portability, and easy use along with a range of  interchangeable probes crafted for various applications. 

MarqMetrix All-In-One Process Raman Analyzer

The MarqMetrix All-In-One Process Raman Analyzer and specialized probes use patented Thermo Scientific TouchRaman Immersion Technology, allowing you to obtain Raman measurements with the MarqMetrix All-In-One Process Raman Analyzer by just touching the end of the Thermo Scientific MarqMetrix BallProbe Sampling Optic to the sample. With its short focus length, the MarqMetrix BallProbe Sampling Optic can precisely examine liquids, solids, slurries, powders, and heterogeneous mixes while reducing the chances for operator error.

 

The MarqMetrix BallProbe Sampling Optic technology utilizes an exclusively sourced, high-grade spherical sapphire lens. The short focal length of the spherical optic allows for simple TouchRaman Immersion Technology sampling. Users simply touch the probe to the sample and collect reproducible spectra of liquids, solids, slurries, powders, and heterogeneous mixtures. The MarqMetrix BallProbe Sampling Optic allows non-specialists to collect high-quality data and eliminates user-to-user variation.  

MarqMetrix Process BallProbe Sampling Optic

The Thermo Scientific MarqMetrix Process BallProbe Sampling Optic is ideal for extreme environments. Offered in Hastelloy C-276, this probe is ultra-resilient for applications that require exposure to harsh chemicals and intense environments. The MarqMetrix Process BallProbe Sampling Optic is available in two standard diameters and chassis length options.

Features and benefits 

  • Immersion contact probe for touch measurements
  • Samples liquids, solids, slurries, powders, and heterogeneous mixtures
  • Simple design for measurement accuracy and reproducibility
  • Designed to withstand challenging chemical, pressure, and temperature conditions

MarqMetrix Performance BallProbe Sampling Optic

The Thermo Scientific MarqMetrix Performance BallProbe Sampling Optic is designed to withstand moderate chemical environments in laboratory and industrial settings. The standard 0.5” diameter MarqMetrix Performance BallProbe Sampling Optic utilizes our largest spherical sapphire ball lens and 316L SS, enabling highly sensitive TouchRaman Immersion Technology measurements across a wide range of sample types. The MarqMetrix Performance BallProbe Sampling Optic comes in three standard diameters and chassis length options.

Features and benefits

  • Accurate and repeatable measurements
  • Samples liquids, solids, slurries, powders, and heterogeneous mixtures
  • Wide range of chemical compatibility and resistance to high-temperatures
  • Ease of use eliminates user-to-user variation

MarqMetrix BioReactor BallProbe Sampling Optic

Designed for Biotech, the Thermo Scientific MarqMetrix BioReactor BallProbe Sampling Optic has a short focal length that measures both liquid media and solids and has the same form factor as industry-standard DO probes.

Features and benefits

  • Accurate and repeatable measurements
  • Durable design, autoclavable (CIP/SIP)
  • Protective cap shields the probe's internal optics during autoclaving and storage
  • Compatible with standard Pg 13.5 ports
  • Easy to use, eliminates user-to-user variation

MarqMetrix Single Use BioReactor BallProbe Sampling Optic

The Thermo Scientific MarqMetrix Single Use BioReactor BallProbe Sampling Optic is designed to be sterilized and to enable precise and repeatable Raman measurement of liquids and solids without affecting the purity of your batch. This MarqMetrix Single Use BioReactor BallProbe Sampling Optic is designed to fulfill the necessities of industries like biopharma and industrial fermentation. It is made of sanitary finished (15Ra) 316 stainless steel and high-purity sapphire optics.

 

This MarqMetrix Single Use BioReactor BallProbe Sampling Optic is ideal for biopharmaceutical and pharmaceutical manufacturing due to its accurate and reproducible measurements. The probe, which comes in tear-away bags, can be sterilized using an autoclave, steam-in-place (SIP), or EtO, or it can be incorporated into larger single-use systems and gamma sterilized. The sterile probe can easily be connected to the Raman system's fiber optic interface, enabling powerful real-time chemical insights. When the process is completed, the probe can simply be disposed of to ensure batch purity.

 

Features and benefits  

  • Single-use (disposable) Raman probe for high-value batches 
  • Accurate and repeatable measurement of liquids and solids  
  • Designed to be sterilized by autoclave, SIP, EtO, or gamma (probe does not come pre-sterilized)  
  • Compatible with standard Pg13.5 ports  
  • Customization available for integrators  

Other available ballprobe sampling optics:

  • MarqMetrix Performance BallProbe Sampling Optic
  • MarqMetrix Process BallProbe Sampling Optic
  • MarqMetrix Custom BallProbe Sampling Optic
  • MarqMetrix Fiber BallProbe Sampling Optic

MarqMetrix Proximal BallProbe High Volume (HV) Sampling Optic

The Proximal BallProbe HV excels at sampling from a distance and taking measurements of in-motion samples with varying heights. The probe’s long working distance (100mm) can rapidly analyze samples on conveyor belts or rotating drums. Its large sampling area (3.5mm) effectively averages the sample as you take measurements.

Features and benefits 

  • Non-contact analysis of:
    • Samples in motion
    • Samples with variable surface relief
    • Samples with uneven packaging
    • (e.g., pellets)
  • Compact design
    • 100mm working distance for measurement through windows, vials, and bags
    • Large depth of field for measurement of samples of variable size and/or surface thickness

MarqMetrix FlowCell Sampling Optic

The Thermo Scientific MarqMetrix FlowCell Sampling Optic is a sophisticated method for building highly accurate Raman measurements into a continuous flow process. It may be immediately integrated into the flow path using common industry-standard connections. This eliminates the complexities of developing a system with proprietary hardware or attempting to integrate an immersion Raman probe into the flow path.

Features and benefits

  • BallProbe technology integrates directly into the flow path
  • Minimizes dead volume and sample handling requirements
  • Simple design for easy integration
  • Custom flow cell probes: Available with higher pressure/temperature ratings, different materials, custom connections, and internal volumes

MarqMetrix Proximal Probe Sampling Optic

With the Thermo Scientific MarqMetrix Proximal Probe Sampling Optic, you can make better real-time judgments and increase process control without ever coming into contact with samples. The MarqMetrix Proximal Probe Sampling Optic is a high-performance and compact sampling device for applications requiring high-signal Raman analysis of samples in motion via physical barriers and air gaps. Because of its short working distance (8mm) and narrow beam spot size (500 micrometers), the MarqMetrix Proximal Probe Sampling Optic provides high-signal, non-contact measurement via vials, glass bottles, or windows. The sapphire lens of the probe produces an exceptionally strong and clear Raman signal in the fingerprint region.

Features and benefits

  • 8mm working distance for non-contact sampling through windows, vials, and bags
  • Compact design
  • High-signal throughput
  • Exceptional Raman signal in the fingerprint region
  • Can be coupled with the Ramina Process Analyzer for full spectral range measurements of 100-3250 cm-1

For Research Use Only. Not for use in diagnostic procedures.