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Custom Antibody and Protein Bioconjugation ServicesOur antibody and protein labeling services team is here to provide expert bioconjugation to meet your unique needs |
If you need a unique antibody or protein conjugate, save time and resources by letting us take care of it for you. Our custom conjugation services team can provide high-quality conjugates for both research and commercial applications. Partner with us so you can focus your energy on innovation while we deliver the conjugates you need.
Our basic conjugation services include standard lysine conjugation, macromolecule crosslinking, and covalent coupling of beads.
Labeling Chemistry | Lysine | Heterobifunctional crosslink | Covalent coupling |
Label options | Alexa Fluor dyes Alexa Fluor Plus dyes pHrodo dyes LysoLight dyes DyLights FITC Texas Red ADC toxins Biotin | R-PE/APC HRP ConA | Antibodies/Proteins Oligos |
Standard quality control testing | Concentration DOL Free dye check | Concentration DOL Amax/A280 | Concentration Bead diameter sizing |
Minimum scale range | 0.2 mg–1 mg | 0.5–1 mg | 0.5–1 mg |
Estimated yield | 70% | 20–40% | 15–75% |
Our advanced conjugation services include small and large site-specific conjugation, bi-specific antibody production, and 1 to 1 antibody conjugation.
Labeling Chemistry | SiteClick | SiteClick | SiteClick | Lysine or SiteClick |
Label options | Alexa Fluor dyes Alexa Fluor Plus dyes pHrodo dyes LysoLight dyes Novafluors ADC toxins Metal-chelating compounds Biotin | R-PE/APC HRP Qdots | IgG Antibodies | R-PE/APC Oligonucleotides Brilliant polymer dyes
|
Standard quality control testing | Concentration DOL Free dye check | Concentration DOL Free dye check | Concentration DOL Free dye check | Concentration DOL Free dye check |
Minimum scale range | 0.5 mg | 1 mg | 1 mg | 0.5–1 mg |
Estimated yield | 70% | 20–50% | 20–40% | 10–30% |
Our basic conjugation services include standard lysine conjugation, macromolecule crosslinking, and covalent coupling of beads.
Labeling Chemistry | Lysine | Heterobifunctional crosslink | Covalent coupling |
Label options | Alexa Fluor dyes Alexa Fluor Plus dyes pHrodo dyes LysoLight dyes DyLights FITC Texas Red ADC toxins Biotin | R-PE/APC HRP ConA | Antibodies/Proteins Oligos |
Standard quality control testing | Concentration DOL Free dye check | Concentration DOL Amax/A280 | Concentration Bead diameter sizing |
Minimum scale range | 0.2 mg–1 mg | 0.5–1 mg | 0.5–1 mg |
Estimated yield | 70% | 20–40% | 15–75% |
Our advanced conjugation services include small and large site-specific conjugation, bi-specific antibody production, and 1 to 1 antibody conjugation.
Labeling Chemistry | SiteClick | SiteClick | SiteClick | Lysine or SiteClick |
Label options | Alexa Fluor dyes Alexa Fluor Plus dyes pHrodo dyes LysoLight dyes Novafluors ADC toxins Metal-chelating compounds Biotin | R-PE/APC HRP Qdots | IgG Antibodies | R-PE/APC Oligonucleotides Brilliant polymer dyes
|
Standard quality control testing | Concentration DOL Free dye check | Concentration DOL Free dye check | Concentration DOL Free dye check | Concentration DOL Free dye check |
Minimum scale range | 0.5 mg | 1 mg | 1 mg | 0.5–1 mg |
Estimated yield | 70% | 20–50% | 20–40% | 10–30% |
Purification/buffer exchange | Individual fractions | DOL optimization | Custom final packaging/formulation | |
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Optional add-on services include | BSA removal Ascites fluid purification Unique buffer formulations | Individual fractions with a fraction letter | 6 MRs (wide) 3 MRs (narrow) | Lyophilization Non-standard return buffer Final packaging over 20 individual aliquots |
Additional QC testing | |
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Optional add-on services include | Bradford BCA PAGE HPLC purity value HPLC chromatogram Custom CoA |
Special handling | |
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Optional add-on services include | Low endotoxin RNAse free |
Purification/buffer exchange | Individual fractions | DOL optimization | Custom final packaging/formulation | |
---|---|---|---|---|
Optional add-on services include | BSA removal Ascites fluid purification Unique buffer formulations | Individual fractions with a fraction letter | 6 MRs (wide) 3 MRs (narrow) | Lyophilization Non-standard return buffer Final packaging over 20 individual aliquots |
Additional QC testing | |
---|---|
Optional add-on services include | Bradford BCA PAGE HPLC purity value HPLC chromatogram Custom CoA |
Special handling | |
---|---|
Optional add-on services include | Low endotoxin RNAse free |
Our basic conjugation services include standard lysine conjugation, macromolecule crosslinking, and conjugation to beads.
Our custom bioconjugation capabilities also include Invitrogen SiteClick antibody labeling techniques for highly efficient and site-specific antibody conjugation. SiteClick labeling allows for simple attachment of detection molecules far from the antigen-binding domain, helping provide covalent labeling without altering antibody function. Many detection molecules can be site-selectively attached to antibodies, including:
We use SiteClick chemistry to create a set of tetravalent bi-specific antibodies. This enables you to choose which pair of antibodies functions best as a bi-specific. Features of our bi-specific custom conjugation offerings include:
One-to-one antibody conjugation helps ensure precise labeling with high specificity to enhance accuracy and sensitivity in your detection assays. Our one-to-one custom offerings include:
For Research Use Only. Not for use in diagnostic procedures.