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Learn solutions for pharma development
Watch these webinars to discover ways Thermo Scientific extruders and related analytical instrumentation can help you address challenges in pharmaceutical development and manufacturing where API solubility and processing stability, taste-masking, enterics, and specialized dosage forms are critical projects. You’ll discover how these solutions can help provide the shortest path from feasibility studies to production.
Hot melt extrusion webinars
Pharma e-symposium: Advancements in drug development and formulation
Watch this e-symposium to gain insights into the latest research and innovative solutions in drug development and formulation, including hot-melt extrusion for OSD and implants and twin-screw granulation and continuous manufacturing.
Employing hot-melt extrusion as a cost-effective method of increasing solubility of water insoluble APIs
Learn how hot melt extrusion (HME) disperses the drug in the matrix at a molecular level by forming a solid solution, and how it is being used in amorphous solid dispersion, controlled release systems, polymorph generation, novel cocrystallisation (solvent-free continuous cocrystallisation), porous polymeric systems and Process Analytical Technology (PAT).
Producing drug delivery systems for solubility enhancement to implants
Discover how hot melt extrusion (HME) is used in modern pharmaceutical formulation development, from increasing bioavailability to novel drug delivery methods.
Improving solubility with HME webinar series
Enabling strategies for development of HPMCA S-based amorphous solid dispersions by HME
Review the use of solid surfactants to reduce complex viscosity (and thus the processing temperature) of HPMCAS-based ASDs.
Solid dispersions: A super saturated formulations to improve bioavailability of orally administered APIs
Learn how to increase the aqueous solubility of orally administered poorly water-soluble drugs by creating a supersaturation state in the gastrointestinal lumen, thus improving bioavailability.
A closer look into ASD formulations: A talk of two dispersions
Learn more about dispersions produced using hot melt extrusion (HME) with polyvinyl alcohol (PVA) as the matrix polymer and working with solid dispersions as a way to improve absorption by enhancing a drug’s solubility.
Twin-screw granulation/continuous manufacturing webinars
Advances in continuous granulation
Review a modular approach to continuous granulation including technological possibilities from mixing to finished product, and comparison of granulation characteristics from classic batch methods to using a twin-screw extruder.
Webinar: Advances in twin-screw granulation technologies
Learn the basic concept of Twin Screw Granulation (TSG), the influence of process parameters on final product quality and insights into recent advances in TSG continuous manufacturing. Including various quality-by-design approaches that can be used.
Incorporating twin-screw extruders into a continuous manufacturing process
Examine how a modular approach to continuous pharmaceutical processes using twin-screw extruders can help shorten the time from drug development to market.
Simultaneous analysis using rheology and Raman spectroscopy
Raman spectroscopy: A powerful tool in process understanding and development
Learn how simultaneous analysis using rheology and Raman spectroscopy can help you characterize the crystallization behavior of drug delivery systems and help tailor their properties to meet final drug requirements.
Additional resources
For Research Use Only. Not for use in diagnostic procedures.