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Porous graphitic carbon (PGC, Hypercarb™) has unique properties as a stationary phase in high-performance liquid chromatography (HPLC). Its chemical surface properties distinguish it from more conventional LC packings such as bonded-silica gels and polymers. PGC behaves as a strongly retentive alkyl-bonded silica gel for non-polar analytes.
However, its retention and selectivity behavior towards polar and structurally-related compounds is very different from conventional C18 columns.
Thermo Scientific™ Hypercarb Porous Graphitic Carbon LC Columns offer:
Property | To meet requirement of | |
Particle shape: | Spherical | No micropores |
Specific surface area: | 120 m2/g | Retention linearity and loading capacity |
Median pore diameter: | 250 Å | Mass transfer for wide range of analyte shapes and sizes |
Pore volume: | 0.7 m3/g | |
Mean particle diameters: | 3 µm, 5 µm | Analytical HPLC columns |
7 µm | Preparative HPLC columns | |
30 µm | SPE applications | |
Porosity: | 75% | Mass transfer within particles |
% C: | 100% | Chemical stability |
Mechanical strength: | <400=""> | Operational particle stability; pressure gradients in packing process |
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