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Bioprocess Controllers
Consistent bioprocess control designed for scalability
Thermo Scientific HyPerforma GXCore, G3Lab, G3Lite, and G3Pro Controllers provide ease of data transferability and scalability throughout your process. This bioprocess controller series incorporates innovative features that enhance productivity, data quality, and reproducibility required to optimize any process. Integrating flexibility and an open-architecture design, this platform allows the use of third-party vessels, as well as the Thermo Scientific HyPerforma Single-Use Bioreactor (S.U.B.).
Choose a step in the workflow below to identify the ideal Bioprocess Controller
G3Lab Bioprocess Controller
Easy process scale-up or scale-down
The Thermo Scientific HyPerforma G3Lab Controller can control most brands of single-use or autoclavable bioreactors and fermentors that are ≤ 50 L, including stirred-tank and rocking models. The enclosure contains state-of-the-art transmitters along with power supplies, pumps, input/output (I/O) modules, and the hardware required to connect to the control network, providing maximum control capability.
Key features:
- Scalability: ≤ 50 L
- Open-architecture capabilities to integrate with vessels from other suppliers, such as the Eppendorf BioBLU Single-Use Vessels and Sartorius UniVessel Benchtop Bioreactors
- The ability to build and manage complex, multi-feed dosing strategies
- Allows for third-party peripheral integration as needed
View the ordering table to select the bioprocess controller and associated products that best fit your needs. ›
G3Lite Model
G3Lite Bioprocess Controller
Modularity for scale-up
The Thermo Scientific HyPerforma G3Lite Bioprocess Controller is an open-architecture control system that can be integrated with most bioreactors and fermentors - regardless of manufacturer. The system consists of a control tower that leverages intelligent transmitters, mass flow controllers (MFCs), pumps, and sensors. This controller is fully self-contained, mobile, and can be operated as stand-alone (for one vessel) or networked for multiple vessels. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.
Key features:
- Scalability: volumes 50 L to 2,000 L
- Modularity: predefined configurations available for 50, 100, 250, 500, 1,000 and 2,000 L bioreactors
- Touchscreen interface for easy data entry and control
- Stand-alone or networked (for multiple vessels)
- Redundant pH and DO sensors
For volumes ≤ 50 L
The G3Lab Bioprocess Controller, primarily used in drug discovery and R&D is often chosen in the process development phase.
For volumes ≤ 15 L
The GXCore Bioprocess Controller is a cost-effective, compact option, also suitable in the process development phase.
G3Pro Model
G3Pro Bioprocess Controller
Versatility for scale-up
The Thermo Scientific HyPerforma G3Pro Bioprocess Controller contains many of the G3Lite Bioprocess Controller capabilities as an open-architecture, universal controller used to control most bioreactors and fermentors. These controllers enable an additional layer of versatility, allowing mobility and flexibility in terms of providing options for any reconfiguration or application expansion. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.
Key features:
- Scalability: volumes 50 L to 2,000 L
- Open-architecture capabilities to integrate with vessels from other suppliers
- Single or dual cart mount option for easy mobility and reduced footprint
- Touchscreen NEMA interface for easy data entry and control
- Probe configuration options – flexible to connect electrochemical, single-use, or both for pH and DO measurements
- Redundant sensor control mechanism
- Can be adapted for multi-product applications
A stand-alone controller system for one vessel
The G3Lite Bioprocess Controller, primarily used in process development and clinical phases, is also suitable for commercial manufacturing when there is a need to have a stand-alone, modular controller system for one piece of equipment.
View the ordering table to select the bioprocess controller and associated products that best fit your needs. ›
G3Lab Bioprocess Controller
Easy process scale-up or scale-down
The Thermo Scientific HyPerforma G3Lab Controller can control most brands of single-use or autoclavable bioreactors and fermentors that are ≤ 50 L, including stirred-tank and rocking models. The enclosure contains state-of-the-art transmitters along with power supplies, pumps, input/output (I/O) modules, and the hardware required to connect to the control network, providing maximum control capability.
Key features:
- Scalability: ≤ 50 L
- Open-architecture capabilities to integrate with vessels from other suppliers, such as the Eppendorf BioBLU Single-Use Vessels and Sartorius UniVessel Benchtop Bioreactors
- The ability to build and manage complex, multi-feed dosing strategies
- Allows for third-party peripheral integration as needed
View the ordering table to select the bioprocess controller and associated products that best fit your needs. ›
G3Lite Model
G3Lite Bioprocess Controller
Modularity for scale-up
The Thermo Scientific HyPerforma G3Lite Bioprocess Controller is an open-architecture control system that can be integrated with most bioreactors and fermentors - regardless of manufacturer. The system consists of a control tower that leverages intelligent transmitters, mass flow controllers (MFCs), pumps, and sensors. This controller is fully self-contained, mobile, and can be operated as stand-alone (for one vessel) or networked for multiple vessels. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.
Key features:
- Scalability: volumes 50 L to 2,000 L
- Modularity: predefined configurations available for 50, 100, 250, 500, 1,000 and 2,000 L bioreactors
- Touchscreen interface for easy data entry and control
- Stand-alone or networked (for multiple vessels)
- Redundant pH and DO sensors
For volumes ≤ 50 L
The G3Lab Bioprocess Controller, primarily used in drug discovery and R&D is often chosen in the process development phase.
For volumes ≤ 15 L
The GXCore Bioprocess Controller is a cost-effective, compact option, also suitable in the process development phase.
G3Pro Model
G3Pro Bioprocess Controller
Versatility for scale-up
The Thermo Scientific HyPerforma G3Pro Bioprocess Controller contains many of the G3Lite Bioprocess Controller capabilities as an open-architecture, universal controller used to control most bioreactors and fermentors. These controllers enable an additional layer of versatility, allowing mobility and flexibility in terms of providing options for any reconfiguration or application expansion. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.
Key features:
- Scalability: volumes 50 L to 2,000 L
- Open-architecture capabilities to integrate with vessels from other suppliers
- Single or dual cart mount option for easy mobility and reduced footprint
- Touchscreen NEMA interface for easy data entry and control
- Probe configuration options – flexible to connect electrochemical, single-use, or both for pH and DO measurements
- Redundant sensor control mechanism
- Can be adapted for multi-product applications
A stand-alone controller system for one vessel
The G3Lite Bioprocess Controller, primarily used in process development and clinical phases, is also suitable for commercial manufacturing when there is a need to have a stand-alone, modular controller system for one piece of equipment.
View the ordering table to select the bioprocess controller and associated products that best fit your needs. ›
Related products used across the workflow from R&D to manufacturing
TruBio Bioprocess Automation Software
The TruBio software, powered by the Emerson DeltaV Distributed Control platform, provides easy-to-configure process control - eliminating the need to learn automation control programming. Developed for use with all Thermo Scientific controllers, TruBio software is designed to support easy scaling, data integrity and technology transfer and allow the ability to build sophisticated process control strategies. It provides flexibility to incorporate a wide range of equipment and manage multiple data streams from several unit operations. TruBio software has been developed according to GAMP 5 methods, and conforms to regulatory requirements for use in cGMP-compliant processes.
Bioreactor systems from Lab to Commercial Manufacturing
Discover the advantages of a comprehensive bioreactor portfolio, enabling scalability from research to cGMP manufacturing that will allow you to choose the ideal match for your process parameters.
Ordering information
Select the G3Lab Bioprocess Controller and the most commonly paired products from the list below. Please speak to your sales representative to determine which MFCs, bioreactors, and automation software platforms will fit your need.
G3Lab Bioprocess Controllers and HyPerforma Glass and Single-Use Bioreactors
G3Lab Bioprocess Controllers and HyPerforma Rocker Bioreactors and BPCs
Select the G3Lite Bioprocess Controller and the most commonly paired products from the list below. Please speak to your sales representative to determine which MFCs, bioreactors, and automation software platforms will fit your need.
For volumes 50 – 250 L
For volumes 500 – 2,000 L
Please speak to your sales representative to determine the type of G3Pro Bioprocess Controller and its associated products (MFCs, bioprocess equipment, and automation software platforms) will fit your needs.
Related resources
Bioprocessing resources
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing: