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We are always looking to improve your electron microscopy experience, whether through enhanced access to service experts, easy to use step-by-step guides, or hands-on training. We also know your electron microscopy lab requires maintenance to stay in top shape. A critical component of this ecosystem is powerful software that enables you to get the best results possible from your instrumentation. That is why we offer a constant stream of improvements and updates to our software, ensuring you can achieve your goals as quickly and easily as possible.
Questions about software updates? Contact us at UpdateEM.
CryoFlow Introduction
Embedded CryoSPARC Live
Discovery Viewer Ruler
Download Release Notes and Manual for CryoFlow Software 1.25
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Download Release Notes and Manual Athena 1.24 for Life Science
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Description of updates
Contact the service team for a full upgrade of Athena Software. Some features may require additional packages.
Description of updates
Applicable instruments
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Then the new session(s) have a dataset automatically created with the same parameters as the prepared single session.
Watch this tutorial to learn how to use new features in this release.
Note: Legacy EPU Software users having a valid EPU license can upgrade to EPU 3.x. If you have Smart EPU Software, please contact service for a combined EPU and Athena software update. Updating only EPU Software can cause an unexpected behavior.
Download release notes for Smart EPU Software 3.9
Compatibility: Titan SW 3.16.x – 3.21.x / Talos SW: 2.16.x – 2.21.x
For questions, please contact EPU@Thermofisher.com
Description of updates
Watch this tutorial to learn how recently released features can facilitate sample screening.
Note: Legacy EPU Software users having a valid EPU license can upgrade to EPU 3.x. If you have Smart EPU Software, please contact service for a combined EPU and Athena software update. Updating only EPU Software can cause an unexpected behavior.
Compatibility: Titan SW 3.15.x – 3.20.x / Talos SW: 2.15.x – 2.20.x.
For questions, please contact EPU@Thermofisher.com
Description of updates
Watch this tutorial to learn how recently released features can facilitate sample screening.
Note: Legacy EPU Software users with a valid EPU license can upgrade to EPU 3.x. If you have Smart EPU Software, please contact service for a combined EPU and Athena Software update. Updating only EPU Software can cause an unexpected behavior.
Compatibility: Titan SW 3.14.x – 3.19.x / Talos SW: 2.14.x – 2.19.x.
For questions, please contact EPU@Thermofisher.com
Description of updates
Watch this tutorial to learn how recently released features can facilitate sample screening.
Note: Legacy EPU Software users with a valid EPU license can upgrade to EPU 3.x. If you have Smart EPU Software, please contact service for a combined EPU and Athena Software update. Updating only EPU Software can cause an unexpected behavior.
Compatibility: Titan SW 3.13.x – 3.18.x / Talos SW: 2.13.x – 2.18.x.
For questions, please contact EPU@Thermofisher.com
Description of updates
Watch this tutorial to learn how recently released features can facilitate sample screening.
Note: Legacy EPU Software users with a valid EPU license can upgrade to EPU 3.x. If you have Smart EPU Software, please contact service for a combined EPU and Athena Software update. Updating only EPU Software can cause an unexpected behavior.
Compatibility: Titan Cryo-TEM SW 3.12.x – 3.17.x / Talos TEM SW: 2.12.x – 2.17.x.
For questions, please contact EPU@Thermofisher.com
Description of updates
Watch this tutorial to learn how recently released features can facilitate sample screening.
Note: You can upgrade to EPU Software 3.x if you have a valid EPU license. If you have Smart EPU Software, please contact service for a combined EPU and Athena Software update. Updating only EPU Software might break compatibility with processing and smart automation features.
Description of updates
Watch this tutorial to learn how to use Discovery Viewer to identify grid areas for high-quality data acquisition.
Note: You can upgrade to EPU 3.x if you have a valid EPU license. If you have Smart EPU please contact service for a combined EPU and Athena software update. Updating only EPU might brake compatibility with processing and smart automation features.
Compatibility: Titan SW 3.10.x – 3.15.x / Talos SW: 2.10.x – 2.15.x.
For questions, please contact EPU@Thermofisher.com
Description of updates
To obtain update:
Note: You can upgrade to EPU 3.x if you have a valid EPU license. Some of the Smart EPU features will need a full upgrade of Athena performed by service and depend on the existence of certain additional packages.
Description of updates
To obtain update:
Note: You can upgrade to EPU 3.x if you have a valid EPU license. Some of the Smart EPU features will need a full upgrade of Athena performed by service and depend on the existence of certain additional packages.
Description of updates
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*Multigrid availability:
Description of updates
Applicable instruments
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Applicable instruments
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Applicable instruments
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Download release notes for EPU-D Software 1.20.
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The EPU-D 1.15 release does not introduce new features or major improvements. It maintains compatibility with new Titan and Talos TEM software versions.
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Maps now supports the latest TEM server versions for Titan (TEM 3.18) and Talos (TEM 2.18).
Tile set acquisition was enhanced to avoid unnecessary backlash compensation between autofocus and acquisition, while keeping the overall precision of movement during acquisition. Previously, backlash compensation had undesirable consequences when it was applied after autofocus was measured on a first or selected tile, thus leading to out-of-focus results.
You can now save EDS tile sets as templates and use them when creating or stamping new tile sets. Users no longer have to manually re-select EDS acquisition for these new tile sets. All new EDS tile sets retrieve current EDS acquisition parameters from the Velox application automatically when they are created or copied.
Maps now automatically deletes temporary files that are saved on the system during EDS acquisition. Previously, users had to manually delete the temporary files. Note that all important files, including EDS maps and metadata, are retained in the Maps project folder.
Description of updates
When the OptiSTEM autofunction fails to converge, or when the quality of the result is poor, the Maps Software application automatically restores the focus and stigmator values to the last known good state.
Maps Software now supports the latest TEM server versions for Titan (TEM 3.17) and Talos (TEM 2.17) TEMs.
Description of updates
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Maps Software no longer presents the end user license agreement during the application installation process. Instead, it now prompts you to read the end user license agreement immediately after you launch the application.
Applicable instruments
Description of updates
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This release includes new features for Autoloader microscopes (Krios, Glacios, and Arctica):
Minor improvements for EDS detector and heating cycle.
Download release notes for MiCo Software 1.14
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The Biprisms tool is available in the Microscope Software Launcher > Tools > Optics menu.
Description of updates
The minimum dwell-time is restricted to the fastest rate at which no frames will be dropped.
The recommended Cryo Cycle intervals are updated:
To obtain update:
Description of updates
For these improvements, the new BeamCurrentControl calibration must be performed by a Thermo Fisher Scientific engineer.
When the system is in STEM mode, the Electron Dose Control (EDC) functionality:
Conditions and restrictions:
The STEM Mh Mode option is now available on all Titan TEM systems with STEM.
On Spectra S/TEM systems, Lorentz Mode (STEM) is available.
The homing procedure is improved. Before any axis is moved, all axes are checked for error states.
When one or more axes are in an error state, the homing procedure will first attempt recover the error. If recovery fails, the homing procedure will not start.
In preceding software releases the homing procedure would always start and would fail when an axis could not be homed.
If a displayed tooltip mentions a condition, the tooltip is updated immediately according to the changed condition.
For BSL3 compliant systems, the OSD is automatically shut down when a decontamination heating procedure starts.
The homing procedure is improved. Before any axis is moved, all axes are checked for error states.
When one or more axes are in an error state, the homing procedure will first attempt recover the error. If recovery fails, the homing procedure will not start.
In preceding software releases the homing procedure would always start and would fail when an axis could not be homed.
Dual-X detectors are now supported on Talos F200i TEM with a C-Twin lens.
The Beam Diameter as displayed in Tomography on Titan TEM systems is now also available on:
The accuracy of the calculated Beam Diameter is typically ±20%, but this depends on the accuracy of the Focus and Stigmate alignment and on the selected Spot Size.
If a displayed tooltip mentions a condition, then the tooltip is updated immediately according to the changed condition.
For BSL3 compliant systems, the OSD is automatically shut down when a decontamination heating procedure starts.
The homing procedure is improved. Before any axis is moved, all axes are checked for error states. When one or more axes are in an error state, the homing procedure will first attempt recover the error. If recovery fails, the homing procedure will not start.
In preceding software releases the homing procedure would always start and would fail when an axis could not be homed.
Align Genie is no longer available in Sherpa. The functionality that was offered via Align Genie is now available in MiCo.
In SALSA > Transfer Device, an Exchange widget is available for each attached Transfer Device (TD). In this widget, the new Write data function writes the rough transfer position to the TD.
The TEM User Interface can no longer be started by a regular user. Regular users should use MiCo. To gain access to the TEM User Interface, request a supervisor or a Thermo Fisher Scientific engineer to open the Microscope Software Launcher > Tools > Microscope UI Access Provider, enter their credentials and select Provide Access.
To obtain update:
Description of updates
Improved robustness of the beam detection and ellipse fitting algorithms.
High End TEMs:
Mid-Range TEM:
Entry Level TEM:
To obtain update:
High End TEMs:
Mid-Range TEM:
Entry Level TEM:
To obtain update:
Source and HT:
Vacuum:
Optics:
Cameras, filters, and detectors:
Motion and Sample Loaders:
All items below are applicable for Tundra systems:
Applicable instruments
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Description of updates: 2.15.1, 2.15.2
Applicable instruments
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Applicable instruments
Description of updates:
Applicable instruments
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Watch this tutorial to learn how about the latest capabilities in Tomography software 5.19
Download release notes for Tomography Software 5.19
Compatibility: Titan SW 3.16.x – 3.21.x / Talos SW: 2.16.x – 2.21.x.
Description of updates
Compatibility: Titan SW 3.15.x – 3.20.x / Talos SW: 2.15.x – 2.20.x.
Description of updates
Compatibility: Titan SW 3.14.x – 3.19.x / Talos SW: 2.14.x – 2.19.x.
Description of updates
Compatibility: Titan SW 3.13.x – 3.18.x / Talos SW: 2.13.x – 2.18.x.
Description of updates
Compatibility: Titan Cryo-TEM SW 3.12.x – 3.17.x / Talos TEM SW: 2.12.x – 2.17.x.
Description of updates
Compatibility: Titan TEM SW 3.11.x – 3.16.x / Talos TEM SW: 2.11.x – 2.16.x.
Description of updates
Compatibility: Titan SW 3.10.x – 3.15.x / Talos SW: 2.10.x – 2.15.x.
Description of updates
To obtain update:
Description of updates
To obtain update:
Applicable instruments
Free of charge for service contracts
Applicable instruments
Included in service contracts
Applicable instruments
For first-time installations, a 90-day Trial License is available to evaluate the software
Applicable instruments
Free of charge for service contracts
Applicable instruments
Tomography > Automated Acquisition:
No license is required to upgrade from Tomo 4.x to 5.x
Applicable instruments
No license update is required to upgrade from Tomo 4.x to 5.x
Applicable instruments
Free of charge for service contracts
Compatibility: Titan SW 3.16.x – 3.21.x / Talos SW: 2.16.x – 2.21.x.
For more details please visit here.
Description of updates
Compatibility: Titan SW 3.15.x – 3.20.x / Talos SW: 2.15.x – 2.20.x.
For more details please visit here
Description of updates
Compatibility: Titan SW 3.14.x – 3.19.x / Talos SW: 2.14.x – 2.19.x.
For more details please visit here
Description of updates
Compatibility: Titan SW 3.14.x – 3.19.x / Talos SW: 2.14.x – 2.19.x.
For more details please visit here
Description of updates
Compatibility: Titan Cryo-TEM SW 3.12.x – 3.17.x / Talos TEM SW: 2.12.x – 2.17.x.
For more details please visit here
Description of updates
For more information please visit the Velox Software page
Description of updates
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To obtain update:
Description of updates
To obtain update:
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Applicable instruments
Free of charge for service contracts
Note: Inspect 3D should not be installed on Microscope PC.
Applicable instruments
Applicable instruments
Description of updates
Applicable instruments
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Free of charge for service contracts
(25 September 2020)
Thermo Scientific microscopy applications use the MRC2014 data format to store, view, and process images. This document specifies:
(July 2023)
Some cameras can produce EER encoded images. These images are stored in a file format called the EER file format, identified by the extension “.eer”. EER files are based on BigTIFF, but define a number of extensions to this format to store all EER-related information in one file. This document describes the currently implemented file format.
For Research Use Only. Not for use in diagnostic procedures.