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DNA & RNA Extraction Articles, Webinars, and Videos |
Read scientific articles, listen to webinars and watch videos on foundational life science topics and modern research applications. Webinars feature top scientists and innovative business leaders, while videos showcase new biotechnologies and how to guides for Thermo Fisher Scientific instruments and reagents. Download free application notes and learn how to extract samples, isolate analytes and deliver pure results for your research.
Nucleic acid research applications and techniques
Learn about nucleic acid isolation techniques
Battle of Sample Purification
Watch this action-packed explanation of why labs have been switching to automated sample purification. Whether starting from academic labs or biotech basements aspiring to expand, automation techniques can free up time, increase reliability and scale up your research.
Infectious disease research includes scientific studies on bacteria, viruses, fungi and parasites. Scientists in this field work towards the development of diagnostic tests, treatment therapies, vaccine development, and innovative ways to combat these types of pathogens. Pathogens are bacterium, virus, or other microorganism that can cause disease.
To fully address infectious disease researchat scale, new solutions were necessary. Below you can find information and resources that help scientific communities reach a future beyond Sars-CoV-2. Reducing the spread of highly infectious and deadly diseases within the population requires viral surveillance and vaccine development. See how Thermo Fisher Scientific scientists address modern vaccine research and development workflows.
Resources
Infectious Disease Research Resources
Understanding the host cell response to a pathogen can include large-scale omics and discovery approaches, targeted identification of important cells and proteins involved in the immune response—all beginning with optimized preparation of your starting sample.
Webinar
Innovations in Vaccine Research
Thermo Fisher Scientific scientists host webinar on vaccine platforms and attributes. Listen as they discuss breakthroughs in research and development in relation to SARS-CoV-2.
eBook
A Complete “How-To” Guide for Saliva Collection and Testing
This complex biofluid plays a critical role in human physiology and disease pathophysiology. To gain a better appreciation for saliva and its growing use, download our eBook, A Complete “How-To” Guide for Saliva Collection and Testing.
Application note
Evaluation and characterization of microorganisms for STIs
Evaluation and characterization of microorganisms that cause STIs and vaginal disease to support research in syndromic effects for individuals at high risk of contracting STIs. Accurately detect a wide variety of sexually transmitted pathogens.
Latest in lab automation
Trends in lab automation include the ability to accelerate automation in research where laborious and repetitive steps can be a bottleneck, the option to scale up or down with demand as well as versatility of lab space for flexible applications, and a movement towards optimizing end-to-end workflows. Below are resources on automated sample purification methods that can help labs save time and valuable resources.
3D Tour
KingFisher Apex used to purify DNA, RNA, proteins, and cells
Discover cutting edge technology for preparing precious sample types. Experience lab automation using our 3D virtual experience.
Resources
Advantages of automated sample purification
When should you switch from manual to automated sample preparation? When demand is high, and a quick processing time is critical for the research lab.
Article
6 reasons to automate nucleic acid research
Automated sample preparation has filled a gap that occurred when the volume of labs processing samples skyrocketed starting in 2020. But as the volume of samples requiring nucleic acid extraction and analysis grew, labor shortages occurred.
Video
Discover KingFisher Apex Automated DNA Purification
This new instrument combines automation technology for sample handling and robust safety features, reducing the bottleneck in sample processing and supporting increased throughput, consistency, and reproducibility of results.
Lab automation technologies for nucleic acid extraction
Wastewater-based disease surveillance
Wastewater-based disease surveillance is enabled by analyzing RNA within a given sample and is a useful tool for monitoring community spread of viral and bacterial pathogens. Manual processing of wastewater samples for isolation of viral and bacterial targets can be improved by pre-enrichment and detection leveraging RT-qPCR (reverse transcription-quantitative polymerase chain reaction). Access more resources on wastewater surveillance and testing.
Infographic
Streamlined SARS-CoV-2 Wastewater Monitoring
Manual and automated workflows for SARS-CoV-2 detection in wastewater samples using Applied Biosystems MagMAX Microbiome Ultra Nucleic Acid Isolation Kit and automated on the Thermo Scientific KingFisher Flex Purification System.
Article
A Brief History of Wastewater Testing and Pathogen Detection
What if we could use wastewater to identify and address the next infectious disease, even before the community itself is aware of the concern? Wastewater surveillance is developing as a powerful tool for public health sector and one with history centuries old.
Protocol
Wastewater sample processing with MagMAX Wastewater Ultra Nucleic Acid Isolation Kit, with Virus Enrichment
Wastewater and sewage surveillance are useful tools for monitoring the regional spread of viral and bacterial pathogens. Surveillance has been shown to be a reliable way to detect SARS-CoV-2 before it becomes widespread in a population.
Resources
Explore tools and resources for wastewater surveillance testing
Infectious pathogen surveillance from wastewater and fecal samples is a method for monitoring their emergence and re-emergence. Wastewater samples must be concentrated and then extracted for improved detection and analysis.
Essential DNA extraction techniques
Starting your human microbiome research
Human microbiome research is the systematic investigation into the composition, structure and function of microbiota found in the human body. The human microbiome is made up of bacteria, fungi, archaea, protists and viruses and researchers use extraction and analysis tools to better understand a target microbe. Learn how to start your microbiome research with nucleic acid extraction articles and videos.
eBook
eBook: The Human Microbiome Frontier
A variety of factors, including diet and lifestyle, can influence our human microbiome and have positive or negative impacts on an individual’s health. Learn how to go from sample to analysis in this free eBook.
Video
Mapping the Journey of Dr. Christopher Mason through the world of Microbiome
See the exciting journey through time and space with Dr. Christopher Mason. Learn where it all began and how he has taken his research to space and back.
Article
Microbiome Q&A with Bio-Me
To learn more about the power of PMP, we sat down with a scientist from Bio-Me for a Q&A. We discuss gaps in microbiome analysis, and how Bio-Me is closing them.
Article
The Human Microbiome: New Frontiers in Medical Research
The human microbiome is a community of microorganisms, including bacteria, archaea, fungi, protists, and viruses that live in the human body, a topic with many unknowns and fascinating complexity.
Cancer research and preclinical studies
The field of cancer research continues to expand with new technologies. The first steps involve sample collection and sample preparation required for the extraction and purification of RNA from a liquid biopsy sample or FFPE (Formalin-Fixed Paraffin-Embedded). The articles, webinars and application notes below focus primarily on preclinical studies. These studies are often done in cancer cells either in a petri dish or in an animal such as a lab mouse. Learn about how exosomes can show early signs of normalcy or malignancy of cancer. Learn more on our cancer research resource page.
Application note
SpeciMAX Saliva Collection Kits stabilize miRNA in saliva samples
Oncology researchers have published research documenting how cancer influences biomarkers of salivary microRNAs (miRNAs) by altering their genetic expression. This study evaluated extraction of miRNAs from saliva.
Application note
A convenient, solvent-free deparaffinization method for FFPE sample preparation
Formalin-fixed paraffin embedded (FFPE) is the most common preservation method to archive solid tissue samples. Here, we present a novel solvent-free method to deparaffinize FFPE samples using AutoLys M tubes.
Resource
Using Cells-to-CT kits to prepare RNA
Learn how to prepare RNA for gene expression analysis from cultured cells, without the need for RNA purification. Fast track to RT-qPCR in only 7 minutes.
Webinar
RNA Extraction from Organoids and Spheroids
Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology, disease modeling, and regenerative medicine. Learn from our Thermo Fisher scientists about new RNA extraction methods and workflows directly from the bench.
For Research Use Only. Not for use in diagnostic procedures.