Conceptual art of a rabbit overlayed on a cell

What is rabbit serum?

Rabbit serum is used in cell culture as a media supplement and can provide cells with proteins, hormones, nutrients, and other factors necessary for growth. Rabbit serum can be used as an alternative to FBS in some cell culture applications and is collected from animals typically six months old or younger. Gibco rabbit sera is processed and manufactured in the United States.

Rabbit serum uses

Rabbit icon
  • Rabbit serum can be used in antibody purification as a serum source for IgG binding proteins (A, G, and L).
  • As a blocking serum in immunocytochemistry and immunohistochemistry, rabbit serum is sometimes combined with BSA [1,2]. Thermo Fisher Scientific also offers normal rabbit serum tested for performance in a variety of immunoassays.

Rabbit serum quality testing

Each lot of rabbit serum is tested for its ability to support the growth of Sp2/O-Ag14 (murine myeloma) cells in control medium containing the test lot of serum. Results are compared to those obtained using control growth medium with a previously characterized reference serum.

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Publications
  1. Fröhlich E, Brossart P, Wahl R. (2001) Effects of retinoids on porcine thyrocytes under different culture conditions. Histochemical J 33(5):295–304. 
  2. Schrans-Stassen BH, Saunders PT, Cooke HJ, et al. (2001) Nature of the Spermatogenic Arrest in Dazl −/− Mice. Biology Of Reproduction 65(3):771–776. 

Resources

Fetal Bovine Serum Basics
Learn the basics of FBS for cell culture, including information on the FBS uses, components, and the market dynamics driving this industry.

Cell Culture Basics
Learn the fundamentals of cell culture for achieving consistent results, including laboratory setup, safety, and aseptic techniques.

Gibco iMatch Sera Lot Matching Tool 
Provide your previous Gibco FBS lot number or answer a few questions to find your ideal serum match.

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For Research Use or Further Manufacturing Use only. Serum and blood proteins are not for direct administration into humans or animals.

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