Stem Cell Reprogramming Tools | Thermo Fisher Scientific

Reprogramming somatic cells to induced pluripotent stem cells is a critical and potentially time intensive step in your stem cell research. That’s why we offer choices in integration-free reprogramming technologies and services that fit your research and translational needs including our Cell Therapy Systems (CTS) Products, which are designed for clinical and translational research applications. We also provide services – you can do it yourself or let us do it for you.

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Which reprogramming product or service is right for you?

	Episomal iPSC Reprogramming Vectors*	Epi5 Episomal iPSC Reprogramming Kit**	CytoTune-iPS 2.0 Sendai Reprogramming Kit	CTS CytoTune-iPS 2.1 Sendai Reprogramming Kit	Stem Cell Research Services - Reprogramming
	Order	Order	Order	Order	Inquire
Description	Proven technology for viral-free iPSC generation	High-efficiency viral-free system requiring no small molecules	Highest efficiency integration-free reprogramming system	High-efficiency reprogramming system for clinical research	Pluripotent stem cells with your genetic background of interest and world-class support, delivered to you
Reprogramming Efficiency	0.002–0.08%	0.04–0.3%	0.02–1.2%	0.01–0.6%	0.02–1.2%
Genes utilized	Thomson/ Yamanaka factors	Yamanaka factors +Lin28	Yamanaka factors	Yamanaka factors Klf4, Oct4, Sox2 and L-myc	Yamanaka factors
Training and expertise required	Moderate	Moderate	Minimal	Minimal	None; experienced stem cell researchers generate the lines on your behalf
Genomic integration-free	✓	✓	✓	✓	✓
Virus-free reprogramming	✓	✓			✓
Blood cell reprogramming	✓	✓	✓	✓	✓
Transfection products	Neon Transfection System or similar device	Neon Transfection System or Lipofectamine 3000	None	None	None
Reporter available	N/A	N/A	CytoTune-EmGFP Sendai Fluorescence Reporter	CytoTune-EmGFP Sendai Fluorescence Reporter	CytoTune-EmGFP Sendai Fluorescence Reporter

*Commercialized in Partnership with Cellular Dynamics International.
**Designed by Dr. Okita in the laboratory of Professor Yamanaka at the Center for iPS Cell Research and Application (CiRA), Kyoto University.

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