Stealth Select RNAi™ siRNAs

Ready, click, go.

Now you can quickly and easily order Stealth Select RNAi™ siRNA - predesigned RNAi sequences to the majority of human, rat, and mouse genes. Stealth Select  RNAi™ siRNA sequences are synthesized using the same advanced chemistry as all Stealth RNAi™ siRNA, and pre-designed in silico using the BLOCK-iT™ RNAi Designer. In addition, an advanced mismatch alignment search results in Stealth Select RNAi™ siRNA sequences that essentially eliminate concerns of off-target effects. The new, easy-to-use BLOCK-iT™ RNAi Express search engine allows you to quickly identify and order Stealth Select RNAi™ siRNA by keyword, accession number, pathway, or gene family.

Order Stealth Select RNAi™

Ready-to-order Stealth Select RNAi™ siRNA provides:

• All of the advantages of Stealth RNAi™ siRNA chemistry: reduced off-target and non-specific effects for clearer results, added stability in serum, and effectiveness up to two weeks in cell culture
• Fast and easy ordering--use the BLOCK-iT™ RNAi Express search engine
• Three non-overlapping sequences supplied individually--experiments can be validated using independent sequences; ensures compatibility with publication requirements
• Higher reduction of off-target effects--application of an advanced specificity search, in addition to BLAST

Get guaranteed results with Stealth Select 3 RNAi™  sets
With Stealth Select RNAi™ siRNA the work of designing highly effective sequences has been done for you. The development of these molecules begins with identifying all human, rat, and mouse transcripts in the Unigene database. In four steps we select highly effective in silico-designed sequences (Figure 1).

Figure 1.  How Stealth Select RNAi™ siRNA sequences are designed.

Guarantee*: With the purchase of a Stealth Select RNAi™ siRNA Set, you will get guaranteed results that at least 2 out of the 3 sequences will result in at least 70% transcript knockdown, given that the transfection efficiency in your experiment is at least 80%.

Ordering Information

Check out how easy it is to identify the Stealth Select  RNAi™ sequences that will target your human, rat, and mouse genes. Use the convenient BLOCK-iT™ RNAi Express search engine. If you are already a Stealth Select RNAi™ siRNA user, reorder one or more of your sequences using the Stealth Select RNAi™ siRNA unique identifier and entering it into the Stealth RNAi™ Quick Order tool.

The following table outlines various options.

The BLOCK-iT™ RNAi Express search engine also includes Validated Stealth RNAi™ siRNA - up to two, non-overlapping bench-tested Stealth RNAi™ siRNA duplexes, each guaranteed to be 100% effective at silencing your target of interest. Or find out more about all the available synthetic formats for RNAi.

*Please contact Invitrogen Technical Services in your region to take advantage of this offer. Be prepared to fax or email your order reference number, oligonucleotide sequences and data showing your transfection efficiency