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Ion Chromatography Mass Spectrometry (IC-MS)
Increase the power of IC with MS detection
Utilize mass detection when you need to ensure analytical confidence and dramatically improve the detection capability of your Thermo Scientific Dionex Integrion or ICS-6000 HPIC system. Ion chromatography with mass spectrometry (IC-MS) maximizes the ability to detect and quantify unexpected co-elutions of components and to confirm trace components.
Browse our complete portfolio below, or let one of our experts help you tailor a selection specific to your application and workflow needs.
IC-MS systems
Coupling MS with your IC can give you more information from every sample:
- Higher sensitivity
- Accurate quantitation
- Peak confirmation and evaluation of chromatographic peak purity
- Increased efficiency
Single Quadrupole IC-MS
Easily master MS for your IC applications.
An easy-to-use, high-performance benchtop system, the Thermo Scientific ISQ EC MS system offers more information about your sample than ever before with increased sensitivity and quantitative accuracy.
Triple Quadrupole IC-MS
Need sensitive, fast, and robust quantitation of a variety of molecule types? For complex samples, the high sensitivity and selectivity of MS/MS using selected reaction monitoring (SRM) provides the most precise and accurate quantitation using IC-MS.
Exceed the most stringent analytical requirements for quantitative performance. Get attogram-level sensitivity in a system that’s exceptionally robust and easy to use.
The TSQ Quantis MS helps you achieve unprecedented experimental sensitivity for all molecular species in complex matrices without sacrificing robustness.
Orbitrap IC-MS
Thermo Scientific Orbitrap mass spectrometers generate high-resolution and accurate-mass data, thereby enhancing sensitivity in trace analyte detection, characterization, and quantitation. That's why they are used in research applications—in particular, life science applications such as metabolomics.
Get a superior combination of scan speed, high resolution, mass accuracy, spectral quality and sensitivity for untargeted or targeted screening and a broad range of qualitative and quantitative applications in environmental, food safety and metabolomics.
Use this system for IC-MS in life science metabolomics research to analyze the most challenging low-abundance, high-complexity samples, to identify more compounds faster, quantify more accurately, and to elucidate structures more thoroughly.
Orbitrap Exploris Mass Spectrometers
Thermo Scientific Orbitrap Exploris mass spectrometry produces quantitative high-resolution, accurate-mass (HRAM) liquid chromatography mass spectrometry (LC-MS) with high quantitative accuracy and precision for your laboratory. You can meet your exact analytical requirements and translate your results more rapidly and simply than ever before with Orbitrap Exploris mass spectrometry.
Accelerate qualitative and quantitative confidence with consistently accurate data delivered by proven technology whether it's for method development or everyday testing, get the operational simplicity, productivity and ruggedness required for your analysis.
Get performance and versatility to drive discovery and identification with the quantitative precision and accuracy to confidently scale up while achieving operational simplicity with intelligent data acquisition helps you discover your fast track to confident results across a range of applications, by using proven technology you can address any challenge and achieve your objectives with excellence.
Achieve a new standard in performance to study trace samples with extraordinary accuracy, certainty, confidence, and simplicity with the quantitative performance to solve your most complex challenges with ease, and the proven qualitative performance you expect in mass spectrometry. From exploratory to targeted quantitation, find the power and reliability to make large scale studies possible, while reducing everyday hassles as you increase productivity within a compact footprint.
Single Quadrupole IC-MS
Easily master MS for your IC applications.
An easy-to-use, high-performance benchtop system, the Thermo Scientific ISQ EC MS system offers more information about your sample than ever before with increased sensitivity and quantitative accuracy.
Triple Quadrupole IC-MS
Need sensitive, fast, and robust quantitation of a variety of molecule types? For complex samples, the high sensitivity and selectivity of MS/MS using selected reaction monitoring (SRM) provides the most precise and accurate quantitation using IC-MS.
Exceed the most stringent analytical requirements for quantitative performance. Get attogram-level sensitivity in a system that’s exceptionally robust and easy to use.
The TSQ Quantis MS helps you achieve unprecedented experimental sensitivity for all molecular species in complex matrices without sacrificing robustness.
Orbitrap IC-MS
Thermo Scientific Orbitrap mass spectrometers generate high-resolution and accurate-mass data, thereby enhancing sensitivity in trace analyte detection, characterization, and quantitation. That's why they are used in research applications—in particular, life science applications such as metabolomics.
Get a superior combination of scan speed, high resolution, mass accuracy, spectral quality and sensitivity for untargeted or targeted screening and a broad range of qualitative and quantitative applications in environmental, food safety and metabolomics.
Use this system for IC-MS in life science metabolomics research to analyze the most challenging low-abundance, high-complexity samples, to identify more compounds faster, quantify more accurately, and to elucidate structures more thoroughly.
Orbitrap Exploris Mass Spectrometers
Thermo Scientific Orbitrap Exploris mass spectrometry produces quantitative high-resolution, accurate-mass (HRAM) liquid chromatography mass spectrometry (LC-MS) with high quantitative accuracy and precision for your laboratory. You can meet your exact analytical requirements and translate your results more rapidly and simply than ever before with Orbitrap Exploris mass spectrometry.
Accelerate qualitative and quantitative confidence with consistently accurate data delivered by proven technology whether it's for method development or everyday testing, get the operational simplicity, productivity and ruggedness required for your analysis.
Get performance and versatility to drive discovery and identification with the quantitative precision and accuracy to confidently scale up while achieving operational simplicity with intelligent data acquisition helps you discover your fast track to confident results across a range of applications, by using proven technology you can address any challenge and achieve your objectives with excellence.
Achieve a new standard in performance to study trace samples with extraordinary accuracy, certainty, confidence, and simplicity with the quantitative performance to solve your most complex challenges with ease, and the proven qualitative performance you expect in mass spectrometry. From exploratory to targeted quantitation, find the power and reliability to make large scale studies possible, while reducing everyday hassles as you increase productivity within a compact footprint.
Which mass spectrometer do I choose?
| Mass Spectrometer | Analyzer | Mode of Operation | MS | MS/MS | Sensitivity | Peak Confirmation | Structural Elucidation |
|---|---|---|---|---|---|---|---|
| ISQ EC MS | Quadrupole | Single ion monitoring (SIM) |  |  |  | | |
| TSQ Altis MS | Triple Quadrupole | Selected reaction monitoring (SRM) | | | |  | |
| TSQ Quantis MS | Triple Quadrupole | Selected reaction monitoring (SRM) | | | | | |
| Q Exactive MS | Orbitrap mass analyzer | High Resolution Accurate Mass (HRAM) | | | | | |
| Orbitrap Fusion MS | Orbitrap mass analyzer | High Resolution Accurate Mass (HRAM) | | | | | |
| Orbitrap Exploris MS | Orbitrap mass analyzer | High Resolution Accurate Mass (HRAM) | | | | | |
| = Not applicable |  = Poor | = Good | = Better | = Best |
IC-MS basics and benefits videos
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