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Charcoal-stripped fetal bovine serum is FBS that has been treated with activated carbon to remove non-polar/lipophilic components (i.e., steroids, growth factors, and some cytokines) regardless of molecular weight with little effect on salts, glucose, amino acids, etc.
Charcoal-stripped FBS is used when studying the impact of steroids on cells in culture. With low levels of lipophilic components in the basal serum/media, androgens, fatty acids, or other molecules of interest can then be added at desired concentrations to study their effects.
Watch to discover why the removal of androgens and small molecules in charcoal-stripped FBS and dialyzed FBS are so important in cancer research.
* These results are based on a review of approximately 10,000 publications using query terms based on six specialty FBS products offered by Thermo Fisher Scientific. These terms were generated by the MeSH (medical subject headings) taxonomy based on the full text of the paper.
Fetal Bovine Serum Basics
Learn the basics of FBS for cell culture, including information on the FBS uses, components, and the market dynamics driving this industry.
Cell Culture Basics
Learn the fundamentals of cell culture for achieving consistent results, including laboratory setup, safety, and aseptic techniques.
Gibco iMatch Sera Lot Matching Tool
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Cell Culture & Transfection Support Center
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For Research Use or Further Manufacturing Use only. Serum and blood proteins are not for direct administration into humans or animals.