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TSQ Mass Spectrometer Product Comparison

Different applications require different levels of system sensitivity, resolution, and speed. In this table, we compare different TSQ triple quadrupole systems in order to showcase which ones are most relevant to your laboratory's needs. For more information on these systems, click on our Smartnote: Transitioning to Confident Quantitation – in search of a better tomorrow



Product comparison

Triple Quad Product ComparisonFortisEnduraQuantisAltis
Sensitivity+++++++++++++++
Resolution+++++++++
Scan Speed+++++++++++++++
Applications across multiple matrices
Targeted quantitation in ProteomicsNoYesYesYes
Peptide and protein quantitation (Biopharma)NoYesYesYes
Small molecule quantitation (Pharma, Clinical Research)YesYesYesYes
Small molecule mixture quantitation (Environmental Safety, Food Safety, Forensic Toxicology, Pharma)YesYesYesYes
Analysis and targeted quantitation of trace impurities (Impurity Quantitation)YesYesYesYes
Targeted quantitation in Omics (metabolomics, lipidomics)YesYesYesYes
Critical Features
MRM for reliable identificationYesYesYesYes
Multiple Source CompatibilityYesYesYesYes
High Resolution SRM: for increased selectivity and sensitivity for analytes or multiple analytes in complex matrices+++++++++
Segmented quadrupoles for increased ion efficiencyYesNoYesYes
Neutral blocker for increased robustnessYesYesYesYes
Increased dynodes in detector for increased lifetime and better linear dynamic rangeYesNoYesYes
APCI compatible with HESI sourceYesNoYesYes
Polarity Switching: Fast switching with stabilization enable faster quantitation assays for every molecule type++++
System Remote MonitoringYesYesYesYes
Assist with 21 CFR Part 11 Compliance (appropriate software)Yes. With LCQUAN™ SoftwareYes. With LCQUAN™ SoftwareYes. With LCQUAN™ SoftwareYes. With LCQUAN™ Software
Instrument IQ/OQ assistYesYesYesYes
Thermo Fisher Cloud: Access, process, review data whenever you like, from wherever you areNoYesYesYes
Wi-Fi Connectivity: Access your data, Check your assay performance remotelyYesYesYesYes
Size27x30x33 (in)27x30x33 (in)27x30x33 (in)27x30x33 (in)
IVD PlatformNoAvailable in certain countriesNoNo
Compatible separation technologiesUltiMate, Vanquish, Multiplexing, Capillary LC, Other vendorsUltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLCUltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLCUltiMate, Vanquish, Other vendors, IC, Multiplexing, Capillary LC, NanoLC
Compatible Software?Xcalibur, TraceFinder, ChromeleonXcalibur, TraceFinder, ChromeleonXcalibur, TraceFinder, ChromeleonXcalibur, TraceFinder, Chromeleon
Library availabilityYesYesYesYes
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TSQ Quantum Access MAX Triple Quadrupole Mass Spectrometer


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