Gene Expression Solutions | Thermo Fisher Scientific

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Explore the most complete offering of gene expression solutions to pick what’s best for your project

We offer a wide range of high-quality solutions for gene expression profiling, verification, and screening. Choosing a gene expression technology is no time for experimentation. Whether you’re running digital or real-time PCR, microarrays, or next-generation sequencing (NGS), we can guide you through our full range of solutions so you don’t end up with a solution that’s too expensive or too complex for what you need.

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Which RNA analysis products are right for the insights you are looking for?

Gene transcription is an intricate and dynamic process that generates a variety of RNA types. An important consideration before the application of NGS in human disease research is whether to interrogate the whole transcriptome, targeted genes or regulatory elements. Find the correct solution to match your needs.

Explore qPCR solutions ›	Reassess microarrays ›	Discover branched DNA tools ›	Opt for Sequencing ›

Applied Biosystems TaqMan Assays	Applied Biosystems Clariom assays	Invitrogen QuantiGene RNA assays	Ion Torrent NGS technology
Spend your time generating results, not designing and optimizing assays.Take advantage of bioinformatics expertise for high quality designs Detect virtually any gene product with more than 2 million predesigned assays and custom designs for everything else Affordable assays for nearly every human, mouse, and rat gene in the RefSeq database Available for 28 species and some pathogens Assays for multiple locations per transcript and across nearly every exon junction in humans The Custom TaqMan Assay Design Tool lets you design and order a TaqMan Assay to detect any gene from any organism	Perform comprehensive, detailed analysis of coding and long noncoding genes, exons, and splice variants with Clariom D assays Rapidly generate robust expression profiles from all well-annotated genes with Clariom S assays Generate expression profiles from as little as 100 pg of total RNA and as few as 10 cells Analyze RNA from a wide variety of sample types, including cells, whole blood, and fresh/fresh-frozen or formalin-fixed, paraffin-embedded(FFPE) tissues. No need for globin or ribosomal RNA removal Perform simple and fast transcriptome analysis with free Transcriptome Analysis Console (TAC) Software designed for biologists	No RNA purification required, works directly with blood and degraded RNA from FFPE samples QuantiGene Singleplex assays use a sandwich nucleic acid hybridization method followed by branched DNA-based signal amplification, performed in a 96- or 384 well plate and detected using a standard luminometer QuantiGene Plex assays provide an accurate and precise method for multiplexed gene expression quantitation using Luminex xMAP technology Measure up to 80 genes of interest and housekeeping genes in the same well with no cross-reactivity with QuantiGene assays with Luminex 100/200, FlexMAP™ 3D, and MAGPIX instruments	Solutions for whole transcriptome RNA-seq, targeted RNA sequencing and small RNA sequencing Use as little as 1 ng of input RNA with Ion AmpliSeq technology Survey differential gene expression profiles and discover novel biomarkers with the scalable throughput of the Ion GeneStudio S5 series Go from RNA to data in less than two days Simplified data analysis with end-to-end bioinformatics solutions

Invitrogen QuantiGene RNA assays

For Research Use Only. Not for use in diagnostic procedures.

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Format	Single-tube TaqMan Assays	TaqMan array plates (96- and 384-well)	QuantiGene Plex assays (96- and 384-well)	TaqMan array cards	OpenArray plates (3,072-well)	Ion AmpliSeq panels	Ion AmpliSeq transcriptome kit	Clariom S gene- level assays	Ion Total RNA- Seq whole- transcriptome kit	Clariom D transcriptome -level assays
Targets per run	Few	8–95	3–80	12–384	18–896	12–1,200+	>20,000	>20,000	>90,000	>540,000
Samples per day	Up to 384	Up to 384/768 fast	Up to 480	Up to 32	Up to 800	Up to 192	Up to 32	Up to 192	Up to 32 (3–4 for human, mouse)	Up to 48

Analysis type	Objective	Potential solutions
Transcriptome: exon-level discovery	Analyze complete set of RNA transcripts (coding, splice variants, and lncRNA) produced by the genome	Ion Total RNA-Seq v2 Kit Clariom D assays—human, mouse, rat
Transcriptome: gene-level discovery (transcripts)	Analyze complete set of RNA transcripts (coding) produced by the genome	Clariom S assays—human, mouse, rat Ion AmpliSeq transcriptome kit—human, mouse Ion Torrent Oncomine Immune Response Research Assay
Alternative splicing	Evaluate eukaryotic gene regulation at the RNA processing level in which different mRNA molecules (isoforms/variants) are produced from the same primary transcript	Clariom D assay Ion Total RNA-Seq v2 Kit
Long noncoding RNA (lncRNA)	Study non–protein-coding transcripts (>200 nucleotides), which are abundant in the mammalian transcriptome, have been shown to regulate transcription, and have been implicated in a wide range of developmental processes and diseases	Ion Total RNA-Seq v2 Kit Clariom D assays—human, mouse, rat TaqMan Assays
miRNA	Profile small noncoding RNA (~22 nucleotides) generated from a hairpin structure on a precursor RNA transcribed from a particular gene, and that function in RNA silencing and posttranscriptional regulation of gene expression	Ion Total RNA-Seq v2 Kit Applied Biosystems miRNA microarrays TaqMan Advanced miRNA Assays
Fusion genes and/or fusion transcripts	Interrogate hybrid genes formed from two previously separate genes that can give rise to hybrid proteins or to misregulation of transcription	TaqMan Assays Ion AmpliSeq RNA Lung Fusion Research Panel

Analysis type	Objective	Potential solutions
All RNA types	Confirm gene expression profiles of biological samples by reliable complementary techniques	Ion AmpliSeq RNA panels Clariom S or D assays TaqMan Assays (TaqMan Array Cards, OpenArray plates) QuantiGene assays

Analysis type	Objective	Potential solutions
All RNA types	Evaluate the activity of many genes at once to create a global picture of expression patterns	Ion AmpliSeq RNA panels Clariom S or D assays TaqMan Assays QuantiGene assays
miRNA	Profile small noncoding RNA (~22 nucleotides) generated from a hairpin structure on a precursor RNA transcribed from a particular gene, and that function in RNA silencing and posttranscriptional regulation of gene expression	TaqMan Advanced miRNA assays (plates and cards) Applied Biosystems miRNA microarrays