Cell Transfection: High Efficiency Solutions

Transfection (i.e., delivery) of genes, RNA, or proteins into cells is a foundational technique in the life sciences. Successful transfection is critical for a range of applications, including studies of gene expression, gene knockdown (i.e., RNAi), genome editing, and protein expression for biopharmaceuticals. Furthermore, advances in mammalian cell transfection technologies, such as in vivo delivery, have proven invaluable to clinical research, with these techniques playing pivotal roles in the development of vaccines as well as cell and gene therapies.

Need to learn the basics of transfection?

Introduction to transfection Download transfection brochure

Discover Lipofectamine products: trusted transfection reagents

Invitrogen Lipofectamine products are widely used transfection reagents that provide consistent and highly efficient gene delivery in many cell types. Choose from a large selection of Lipofectamine reagents designed to accommodate a range of applications, from in vitro DNA and RNA delivery to in vivo transfection and gene editing.

Browse all Lipofectamine reagents

Need to learn more about the basics of cationic lipid transfection?
Explore cationic lipid transfection

Discover the Neon NxT Electroporation System for high efficiency transfection in difficult cells

The Neon NxT Electroporation System is an innovative electroporation device able to achieve high efficiency transfection and increased cell viability, even in hard-to-transfect cell types.

Explore the Neon NxT electroporation device

Need to learn more about the basics of electroporation?
Learn about the electroporation method

Transfection can be done using chemical, physical, or biological methodologies. Learn about transfection methods, including factors for selecting the transfection reagent or system that is right for your cell type and payload.

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Cell transfection is a fundamental step in a multitude of experimental applications. Whether you are performing academic research to answer core cellular question, expanding into clinical research, or manufacturing recombinant proteins for biopharmaceutical or biotechnological industries, highly efficient cell transfection is critical. Discover an expansive range of transfection applications to fit your experimental needs.

Browse all transfection applications

Whether you are a student, advanced academic researcher, or looking to scale your processes for clinical or industrial purposes, Thermo Fisher Scientific has the resources you need to succeed. This carefully curated resource collection includes learning centers, an extensive FAQ database, and a large library of product guides and application notes for your cell type and payload.

Find the transfection resources and support you need