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Next-Generation Sequencing (NGS)
Interact Reference Component
Next-generation sequencing (NGS) is a high-throughput methodology that enables rapid sequencing of the base pairs in DNA or RNA samples. Supporting a broad range of applications, including gene expression profiling, chromosome counting, detection of epigenetic changes, and molecular analysis, NGS is driving discovery and enabling the future of personalized medicine.
Ion Torrent next-generation sequencing systems
Scalable targeted NGS to support small and large projects
The Ion GeneStudio S5 system is a scalable, targeted-NGS workhorse with wide application breadth and throughput capability.
Specimen to report in a single day with a hands-off, automated workflow*
The Genexus System is the first turnkey NGS solution that automates the specimen-to-report workflow and delivers results in a single day with just two user touchpoints.*
Targeted NGS applications
Cancer research
From basic to translational to clinical research
Complex disease research
For research of genetics, environment, lifestyle factors and beyond
Infectious disease and microbial research
From viruses to microbial communities
Reproductive health
Expanded carrier screening and preimplantation genetic testing for positive impact on families around the world
Human identification (HID)
Forensic DNA analysis and phenotyping, from genotyping to STRs to mitochondrial DNA
Agrigenomics
Simple, scalable and affordable NGS for plant and animal genotyping applications
NGS workflow and data management
Streamline your NGS workflow
How does Ion Torrent NGS work?
Ion Torrent next-generation sequencing exploits the fact that addition of a dNTP to a DNA polymer releases a hydrogen ion. We measure the pH change resulting from those hydrogen ions using semiconductors, simultaneously measuring millions of such changes to determine the sequence of each fragment.
The semiconductor approach—unlike optics or modified nucleotides used in other NGS technologies—helps you implement a fast and simple workflow that scales to your research needs across multiple applications including inherited disease, oncology, infectious disease, human identification (HID), human leukocyte antigen (HLA) typing, and agrigenomics.
Our targeted sequencing approach introduces a PCR-based sequence enrichment step using Ion AmpliSeq technology that focuses on genes or even genetic variants of interest; a good example is the targeting of oncogenes and tumor suppressors in a cancer research study.
NGS Resources
NGS Support
Next-Generation Sequencing Support Center
Find tips, troubleshooting help, and resources for your next-generation sequencing applications.
For Research Use Only. Not for use in diagnostic procedures.