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Heat Transfer
DHX Heat Exchanger
Our innovative modular system uses single-use BioProcess Containers (BPCs) as the sterile fluid path. The BPCs fit tightly between five stainless steel plates, efficiently transferring heat in a counter-current flow path.
The sterile, single-use fluid path makes the system an ideal choice for heat transfer during fermentation, collection of harvest media and protein processing. The DHX Heat Exchanger provides efficient, sterile heat transfer that easily integrates into any process
Benefits of the DHX Heat Exchanger
Key features and benefits
- Completely isolated flow paths for process fluid and heat transfer fluid
- Countercurrent, serpentine flow patterns
- Dimpled jacketing on the plates provides turbulent flow
- BPCs fill in place with no operator interaction
- Modular design and small footprint allows for changing process needs
- Reduced infrastructure requirements and processing time
- Improved product consistency
Applications
- Media hold
- Mixing and fermentation
- Cell separation/protein harvest
- Harvest cooling
- Buffers
- Protein purification
- Bulk drug substance
Countercurrent flow between the heating/cooling fluid and the process fluid
The purple shading depicts the serpentine flow path of the process fluid in the bags. The dimpled plate behind the single-use bag depicts where the heating/cooling fluid flows in a countercurrent fashion to the process fluid in a completely isolated flow path.
Key features and benefits
- Completely isolated flow paths for process fluid and heat transfer fluid
- Countercurrent, serpentine flow patterns
- Dimpled jacketing on the plates provides turbulent flow
- BPCs fill in place with no operator interaction
- Modular design and small footprint allows for changing process needs
- Reduced infrastructure requirements and processing time
- Improved product consistency
Applications
- Media hold
- Mixing and fermentation
- Cell separation/protein harvest
- Harvest cooling
- Buffers
- Protein purification
- Bulk drug substance
Countercurrent flow between the heating/cooling fluid and the process fluid
The purple shading depicts the serpentine flow path of the process fluid in the bags. The dimpled plate behind the single-use bag depicts where the heating/cooling fluid flows in a countercurrent fashion to the process fluid in a completely isolated flow path.
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Related resources
Bioprocessing resources
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing: