Pharma & Biopharma Learning Center

Producers of pharmaceuticals and biologics are challenged to become more efficient in discovering and developing candidate drugs while increasing manufacturing productivity and reducing costs. Advanced instrumental techniques and workflows can help to accelerate the development pipeline and optimize production processes. 

Thermo Fisher Scientific has innovative solutions at every stage of the bio/pharmaceutical process; from discovery through to production and QC. Our deep understanding of the challenges faced by producers of medicines allows us to forge partnerships that deliver next-generation drugs to market quicker.

This application note discusses the importance of proper sample preparation for mAb subunit analysis and to provide optimized LC/MS conditions to achieve conclusive information on the mass of the subunits as well as for performing middle-down analysis for sequence confirmation.

Ultra high-pressure liquid chromatography has become an important analytical tool for meeting these varied needs for higher throughput. Analytical instrument makers believe that further advances in the technology will enable UHPLC to have an even bigger impact on the pharmaceutical industry.

Accounting for the inherent heterogeneity of monoclonal antibodies is essential to ensure production of consistent and safe therapeutics and, in light of this, there is an array of chromatographic and supporting regulatory systems.

Four simple workflows to allow you to understand the form, site, & variation of glycosylation on biotherapeutic proteins. 

Discover our range of products and workflows dedicated to biotherapeutic characterization. From discovery to lot testing, and from aggregate analysis to peptide mapping, we have the solutions you need.

This eBook offers guidance and best practices for the issues that concern the pharma and biotech manufacturing industry the most.

• Vanquish Flex UHPLC System
• MAbPac RP LC Columns
• SMART Digest Kits