Resources on Resin Technology

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Explore resin technology to help advance your purification process

Discover innovative solutions for the purification of unique molecules. Access our resources to help you optimize your the downstream purification of your novel biologics.

Simplify downstream development with Bioprocessing calculators

Articles

Understanding Viral Clearance During Anion Exchange Chromatography by Using a Novel Design of Experiment Approach

Review a method of purification that considers such factors as load pH, virus concentration, and the physical and chemical properties of three different monoclonal antibodies.

Diversity of Single-Domain Antibodies for Purification of Biotherapeutics and Analytical Assays

Learn more about single domain antibodies and how they are ideal ligands to develop a broad array of analytical assays and techniques.

Choosing a Chromatography Resin for the Downstream Purification of Biotherapeutics

Find out how various resin options in the process development toolbox can help you customize the manufacturing processes for your specific biotherapeutic molecule.

Custom Chromatography Solutions for Complex Biotherapeutics Purification

Discover how custom chromatography resins can help overcome purification challenges associated with novel molecules when off-the-shelf chromatography resins aren’t available.

Advantages of Antibody-Based Selectivity in the Purification of Next Generation Biologics

Examine the benefits of affinity chromatography for the purification of novel biologics through several case studies.

eBooks

Advances in Downstream Processing of Complex Antibodies

Gain insight into selecting an affinity chromatography ligand to polish complex mAbs including specificity, capacity, stability, and cost.

Antibody Therapeutic Polishing: Utility of Hydrophobic-Interaction Chromatography

Explore how two clinical antibody-based therapeutics yield aggregate clearance using hydrophobic interaction chromatography for aggressive purification.

Pure and Simple: Affinity Chromatography Solutions for Complex Biotherapeutic Manufacturing

Discover how using affinity purification can help improve biotherapeutic manufacturing of antibody-based therapeutics, mRNA, vaccines, viral vectors, and other novel therapeutics.

Improve Purification Process Efficiency

Learn from specialists as they share their views on enhancing downstream processes for various biomolecules using affinity chromatography.

Posters

POROS Benzyl Ultra Viral Clearance and Impurity Removal for a Novel Antibody Format Used in an Enhanced Antibody Drug Conjugate

Gain knowledge on the use of a hydrophobic interaction resin in reduction of HMW species that are challenging to remove through standard bind and elute cation exchange chromatography.

An innovative Approach to Addressing High Aggregate Challenges in Engineered Monoclonal Antibodies

Explore the performance of a monoclonal antibody purification solution in high-aggregate conditions that support the cation exchange step and the anion exchange-based final polishing step.

Advantage of Antibody-Based Selectivity in the Purification of Biologics

Get more insight into CaptureSelect technology and how it helps solving challenges in the purification of various biologics.

Videos

Affinity Resin Binding Solutions

Discover how our purification solutions can deliver efficient and scalable yields for downstream processing to support your monoclonal antibody downstream process.

Pilot-Scale Column Packing with Thermo Scientific POROS 50 µm Resins

Learn how to pack a pilot-scale column with Thermo Scientific POROS chromatography resins.

Lab-Scale Column Packing with Thermo Scientific POROS 50 µm Resins

Learn how to pack a lab-scale column with Thermo Scientific POROS chromatography resins.

Webinars

DOE Methodology for Downstream Purification of pDNA with Ion-Exchange Resins

Learn about a design of experiment (DoE) study to evaluate and optimize pDNA capture for various downstream purification processes.

Column Packing with Dr. Anna LeBris

Review best practices for packing POROS chromatography resins.

Platform Purification Approaches for the Production of Complex Biologics

Discover robust chromatography tools that can clear more impurities in a single step while maintaining high recoveries and process flexibility for complex biomolecules.

Addressing Purification Challenges for Complex Therapeutics with Custom Chromatography Resins

Learn how our custom resin platform and novel affinity ligand technology enables the development of innovative purification resins, providing a solution for challenging downstream processes.

Understanding Viral Clearance During Anion Exchange Chromatography by Using a Novel Design of Experiment Approach

Understand the outcome of a study on viral clearance study during AEX chromatography to improve effectivity and rigor of viral clearance at this step.

For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.