Introducing our latest in plasmid purification technology

Welcome to the future of automated maxi-scale plasmid DNA purification. The KingFisher PlasmidPro is a innovative, fully automated solution that allows researchers to walk away while the system works. Go from culture to purified plasmid DNA in under 75 minutes with less than 5 minutes of hands-on time. No more laborious, time-consuming plasmid prep.

Experience a benchtop system that yields advanced transfection grade plasmid DNA that is suitable for a range of applications including transfection, protein expression, gene therapy, DNA sequencing, and vaccine development. Scientists in biotech, biopharma, research institutions, service labs, and beyond—prepare for a walk away maxi-scale plasmid purification solution to help accelerate your research.


Learn more about automated plasmid prep with the Kingfisher PlasmidPro



Advantages of automating plasmid DNA isolation steps

Automating plasmid DNA isolation can save time and improve lab efficiency

Automating plasmid DNA isolation can help save time and improve lab efficiency

Automated plasmid preparation can help reduce the time and labor required for plasmid isolation. Manual plasmid DNA isolation can be a time-consuming and repetitive process with risk of human error. By automating plasmid DNA isolation, it can help researchers can save time and improve the overall efficiency of their experiments.

Achieve consistent plasmid DNA quality and yield using automated workflow steps

Achieve consistent plasmid DNA quality and yield using automated workflow steps

Automation enhances the reproducibility and consistency of plasmid DNA isolation. The KingFisher PlasmidPro systems can be programmed to follow standardized protocols precisely, helping minimize variations between different isolations. This can help ensure more reliable and consistent results, which is crucial for accurate data analysis and interpretation.

Produce larger quantities of plasmid for use by eliminating manual steps

Produce larger quantities of plasmid for use by eliminating manual steps

By scaling up plasmid research through automation, researchers can generate large quantities of high-quality plasmid DNA. This can help facilitate the production of recombinant proteins, therapeutic agents, or DNA vaccines on a larger scale.

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Simple automated plasmid purification workflow

The KingFisher PlasmidPro offers a streamlined and user-friendly workflow for plasmid purification. Its simple design and intuitive interface make it easy to operate, even for users with minimal training. With automated steps and precise control, the KingFisher PlasmidPro can help simplify the entire process, from sample loading to elution, helping ensure reliable and efficient plasmid purification every time.

Pouring the overnight fresh culture in prefilled cartridge

Pour the culture

Close the door and press start button

Insert the cartridge into the instrument and press "start​"

Remove the Collect tube and get the purified Plasmid DNA

Collect the tube with purified plasmid DNA in less than 75 minutes


Introducing the KingFisher PlasmidPro



Getting started with automated plasmid purification

The KingFisher PlasmidPro system offers a comprehensive range of key features that set it apart as the exceptional solution for maxi-scale plasmid DNA purification. By selecting the KingFisher PlasmidPro system, you can enhance your productivity and performance in plasmid DNA purification. With its user-friendly interface, efficient automation, and unwavering purification quality, this system helps provide a seamless workflow and consistently delivers quality results.

Hand pushes power button

Installation is fast and effortless​

Set up on benchtop in just minutes by plugging in and turning on—ready to use immediately.

Suitable for users without training

Suitable for users of all skill levels​

Intuitive design makes it simple.  Pour culture and press the “Start run” button.​

product photo

Save valuable time ​

Complete each run in less than 75 minutes, helping ensure a swift and highly efficient workflow.​

DNA graphic

Achieve desirable outcomes​

Optimized for maxi-scale plasmid DNA purification from 100–150 mL bacterial cultures consistently yielding advanced transfection grade Plasmid DNA.​

By selecting the KingFisher PlasmidPro system, you can enhance your productivity and performance in plasmid DNA purification. With its user-friendly interface, efficient automation, and unwavering purification quality, this system enables a seamless workflow and consistently delivers quality results.

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Pre-filled cartridges for automated plasmid prep

The KingFisher PlasmidPro system provides users advanced transfection-grade pre-filled cartridges based on their specific downstream applications. This enables users to achieve the desired level of endotoxin removal, tailored to their unique requirements.​

The endotoxin-free cartridges have a limit of <0.1 EU/µg pDNA​.

Learn more about Plasmid DNA Purity Grades


PlasmidPro performance data

Automated vs. manual plasmid DNA isolation and purification

The KingFisher PlasmidPro system consistently achieves high pDNA concentrations, exceptional elution volumes, and expected total yields, helping ensure reliable and reproducible results. Additionally, the system produces desired A260/A280 and A260/A230 purity ratio values, and preserves a high percentage of supercoiled form, indicating the integrity of the purified DNA. With its exceptional performance, the automated system is an excellent solution for researchers seeking efficient and high-quality maxi-scale plasmid DNA purification.

Figure 1. Row 1–14 samples run through PlasmidPro and row 15–16 samples run through manual column-based kit in 1% agarose gel. L1 is an Invitrogen linearized dsDNA ladder and L2 is the supercoiled pDNA ladder and the supercoiled band of the samples aligns to the 5 kb marker.

 

Resources
  • Protocol Videos—Videos to help you isolate nucleic acids using a variety of techniques.
  • DNA & RNA Selection Guide—Find the right purification products.
  • Videos—View our library of DNA & RNA purification and analysis videos.
  • Application Notes—Explore our application notes from scientists sharing data for isolation products

For Research Use Only. Not for use in diagnostic procedures.