Suzuki Cross-Coupling Reaction

One of the best-known cross-coupling reactions is the Suzuki or Suzuki-Miyaura reaction, where organoboron compounds and organic halides or triflates react in the presence of a palladium catalyst to form carbon-carbon bonds. First reported in 1979, this reaction offers several advantages over other cross-coupling reactions, particularly the Stille reaction, boronic acids being much less toxic and environmentally damaging than the organostannanes.