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Semi-volatile organic pharmaceutical impurities are a complex range of chemicals that often require high selectivity and sensitivity analysis for identification and quantification. Obtain unambiguous impurity identification and quantification with exceptional performance using Thermo Scientific™ Orbitrap™-based mass spectrometry with software that utilizes advanced filtering algorithms and automates library searching. Whether you are analyzing impurities in APIs, intermediates, excipients, or extractables and leachables this powerful workflow delivers a single identification and quantification answer with high confidence.
Bring the power of the first-ever combination of high-resolution gas chromatography (GC) and high-resolution accurate mass (HRAM) Orbitrap mass spectrometry to your laboratory. The Thermo Scientific™ Q Exactive™ GC Orbitrap™ GC-MS/MS system provides comprehensive characterization of samples in a single analysis for the highest confidence in compound discovery, identification, and quantitation. This system offers the quantitative power of a GC triple quadrupole MS combined with the high-precision, full-scan HRAM capabilities that's only available in combination with our Orbitrap technology.
Perform targeted/non-targeted screening, routine quantitation, and qualitative review of GC, GC-MS, LC, and LC-MS data with Thermo Scientific™ TraceFinder™ software. The software provides quantitative workflows and reports for pharmaceutical applications. Discover the unique benefits of TraceFinder with streamlined targeted screening and quantitation for all molecule types and easy access to all necessary information for hundreds of molecules in seconds. Interrogate accurate mass libraries and use high resolution filtering (HRF) to get a single high-confidence answer.
Hear from scientists at AstraZeneca as they use the latest orbitrap based GC-MS/MS technology to solve real world challenges with unknown impurities in API intermediates.