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Co-transfection refers to the simultaneous transfection of two separate nucleic acid molecules into a cell, allowing each to carry out its function within the same cell.
Figure 1. Example of co-transfection. A DNA plasmid and siRNA molecule are co-transfected into a single cell.
Find products, citations, and protocols optimized for your transfection experiments. Input information on your experiment type, cell line, and payload to unlock solutions.
Selecting the right reagent is essential to ensuring co-transfection efficiency and success. Invitrogen Lipofectamine reagents are proven to be effective for co-transfection experiments.
Lipofectamine 3000 reagent uses advanced lipid nanoparticle technology, enabling exceptional transfection performance. It delivers exceptional transfection efficiency into a wide range of difficult-to-transfect and common cell types.
Lipofectamine 2000 reagent is a proprietary formulation that facilitates highly efficient delivery of short interfering RNA (siRNA) or plasmid DNA to mammalian cells.
In addition to these Lipofectamine reagents, explore our wide range of other transfection products.
To see guidelines for ensuring high co-transfection efficiency in RNAi experiments, please visit our protocol for co-transfection of plasmid DNA and RNAi molecules using Lipofectamine 2000 reagent.
View the co-transfection protocol
Visit Transfection Basics to learn more about performing transfection in your lab.
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