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Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
5430437B18Rik; AW048963; biogenesis of lysosomal organelles complex-1, subunit 8; biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; Bloc1s8; DBND; distrobrevin binding protein 1; DKFZp564K192; DTBP1; Dtnbp1; Dysbindin; dysbindin-1; dystrobrevin binding protein 1; dystrobrevin-binding protein 1; FLJ30031; Hermansky-Pudlak syndrome 7 protein; hermansky-Pudlak syndrome 7 protein homolog; HPS7; HPS7 protein; HPS7 protein homolog; Hps7-like protein; MGC20210; My031; OTTHUMP00000221462; OTTHUMP00000221485; RP1-147M19.1; sandy; sdy
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