INPP5E Antibodies

Antibodies that detect INPP5E can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. These antibodies target INPP5E in Human, Mouse and Rat samples. Our INPP5E polyclonal antibodies are developed in Rabbit... Antibodies that detect INPP5E can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. These antibodies target INPP5E in Human, Mouse and Rat samples. Our INPP5E polyclonal antibodies are developed in Rabbit and Mouse. Find the INPP5E... Antibodies that detect INPP5E can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. These antibodies target INPP5E in Human, Mouse and Rat samples. Our INPP5E polyclonal antibodies are developed in Rabbit and Mouse. Find the INPP5E antibody that fits your needs. Choose from 1 of 7 INPP5E antibodies, which have been validated in experiments with 58 publications and 34 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the... Antibodies that detect INPP5E can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. These antibodies target INPP5E in Human, Mouse and Rat samples. Our INPP5E polyclonal antibodies are developed in Rabbit and Mouse. Find the INPP5E antibody that fits your needs. Choose from 1 of 7 INPP5E antibodies, which have been validated in experiments with 58 publications and 34 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

INPP5E (inositol polyphosphate 5-phosphatase), also known as phosphatidylinositol polyphosphate 5-phosphatase type IV, is a 644 amino acid peripheral membrane protein associated with Golgi stacks. Belonging to the inositol-1, 4, 5-trisphosphate 5-phosphatase type IV family, INPP5E converts phosphatidylinositol-3, 4, 5-triphosphate (PtdIns 3, 4, 5-P3) to PtdIns-P2. While inactive towards water soluble inositol phosphates, the activity of INPP5E is specific for lipid substrates. INPP5E becomes phosphorylated upon DNA damage and is expressed in brain, heart, pancreas, testis and spleen. Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1), a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. In addition, mutations in the INPP5E gene may lead to mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS), an autosomal recessive disorder characterized by moderate mental retardation, truncal obesity, congenital non-progressive retinal dystrophy, and micropenis in males.

Synonyms

1200002L24Rik; 5-phosphatase that induces arborization; 72 kDa inositol polyphosphate 5-phosphatase; 72kDa; CORS1; CPD4; inositol polyphosphate 5-phosphatase; inositol polyphosphate-5-phosphatase E; inositol polyphosphate-5-phosphatase, 72 kDa; INPP5E; JBTS1; mKIAA0123; MORMS; Pharbin; phosphatidylinositol 4,5-bisphosphate 5-phosphatase; Phosphatidylinositol polyphosphate 5-phosphatase type IV; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; phosphatidylinositol-4,5-bisphosphate 5-phosphatase; PPI5PIV

INPP5E Antibodies

Target Information

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