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KIRREL (NEPH1) is a member of the nephrin-like protein family, which includes NEPH2 and NEPH3. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. NEPH1 is a member of the nephrin-like protein family, which includes NEPH2. The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003).
6720469N11Rik; FLJ10845; kin of IRRE like (Drosophila); kin of IRRE like 1; Kin of irregular chiasm-like protein 1; kin of IRRE-like protein 1; Kirrel; KIRREL1; MGC129542; MGC129543; NEPH1; nephrin 1; nephrin related; nephrin-like protein 1
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