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The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date.
85 kDa calcium-independent phospholipase A2; 85/88 kDa calcium-independent phospholipase A2; BB112799; CaI-PLA2; Group VI phospholipase A2; GVI; GVI PLA2; INAD1; intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA(2)beta; iPLA2; iPLA2beta; iPLA2-beta; IPLA2-VIA; NBIA2; NBIA2A; NBIA2B; neurodegeneration with brain iron accumulation 2; PARK14; patatin-like phospholipase domain-containing protein 9; phospholipase A2 group VI; phospholipase A2, group VI; phospholipase A2, group VI (cytosolic, calcium-independent); PLA2; PLA2G6; PLPLA9; PNPLA9
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