Product References
Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages by modulating the ERK1/2 pathway.
Scientific reports
Yan C,Kuang W,Jin L,Wang R,Niu L,Xie C,Ding J,Liao Y,Wang L,Wan H,Ma G
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2023
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Veterinary research
Feng L,Luo G,Li Y,Zhang C,Liu Y,Liu Y,Chen H,He D,Zhu Y,Gan L
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in Flow Cytometry
Tue Mar 14 00:00:00 EDT 2023
SIDT1 plays a key role in type I IFN responses to nucleic acids in plasmacytoid dendritic cells and mediates the pathogenesis of an imiquimod-induced psoriasis model.
EBioMedicine
Morell M,Varela N,Castillejo-López C,Coppard C,Luque MJ,Wu YY,Martín-Morales N,Pérez-Cózar F,Gómez-Hernández G,Kumar R,O'Valle F,Alarcón-Riquelme ME,Marañón C
11-0402-82 was used in Flow Cytometry to explore the role of SIDT1, an ER-resident protein expressed in the lymphoid lineage and involved in anti-viral IFN-I responses in vivo, in the main IFN-producing cells, the plasmacytoid dendritic cells.
Tue Feb 01 00:00:00 EST 2022
Nanomaterials-Mediated Co-Stimulation of Toll-Like Receptors and CD40 for Antitumor Immunity.
Advanced materials (Deerfield Beach, Fla.)
Yan J,Zhang Y,Du S,Hou X,Li W,Zeng C,Zhang C,Cheng J,Deng B,McComb DW,Zhao W,Xue Y,Kang DD,Cheng X,Dong Y
11-0402-82 was used in Flow cytometry/Cell sorting to develop an immunotherapy regimen that enables co-stimulation of TLR7/8- and CD40-mediated pathways.
Tue Nov 01 00:00:00 EDT 2022
Intestinal CD11b+ B Cells Ameliorate Colitis by Secreting Immunoglobulin A.
Frontiers in immunology
Fu Y,Wang Z,Yu B,Lin Y,Huang E,Liu R,Zhao C,Lu M,Xu W,Liu H,Liu Y,Wang L,Chu Y
11-0402-82 was used in Flow Cytometry to demonstrate that CD11b+ B cells are essential intestinal suppressive immune cells and the primary source of intestinal IgA, which plays an indispensable role in maintaining intestinal homeostasis.
Fri Jan 07 00:00:00 EST 2022
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
11-0402-82 was used in Flow Cytometry to show that the phosphatase PP2Cδ played a pivotal role in regulating dendritic cells (DC) activation and function, as PP2Cδ ablation caused aberrant maturation, activation, and Th1/Th17-priming of DCs, and hence induced onset of exacerbated experimental autoimmune encephalomyelitis.
Mon Feb 28 00:00:00 EST 2022
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
11-0402-82 was used in Flow Cytometry to show that the phosphatase PP2Cδ played a pivotal role in regulating dendritic cells (DC) activation and function, as PP2Cδ ablation caused aberrant maturation, activation, and Th1/Th17-priming of DCs, and hence induced onset of exacerbated experimental autoimmune encephalomyelitis.
Mon Feb 28 00:00:00 EST 2022
REV7 is required for processing AID initiated DNA lesions in activated B cells.
Nature communications
Yang D,Sun Y,Chen J,Zhang Y,Fan S,Huang M,Xie X,Cai Y,Shang Y,Gui T,Sun L,Hu J,Dong J,Yeap LS,Wang X,Xiao W,Meng FL
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in In vitro Assay
Thu Jun 04 00:00:00 EDT 2020
REV7 is required for processing AID initiated DNA lesions in activated B cells.
Nature communications
Yang D,Sun Y,Chen J,Zhang Y,Fan S,Huang M,Xie X,Cai Y,Shang Y,Gui T,Sun L,Hu J,Dong J,Yeap LS,Wang X,Xiao W,Meng FL
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in In vitro Assay
Thu Jun 04 00:00:00 EDT 2020
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.
Cell reports
Francica P,Mutlu M,Blomen VA,Oliveira C,Nowicka Z,Trenner A,Gerhards NM,Bouwman P,Stickel E,Hekkelman ML,Lingg L,Klebic I,van de Ven M,de Korte-Grimmerink R,Howald D,Jonkers J,Sartori AA,Fendler W,Chapman JR,Brummelkamp T,Rottenberg S
11-0402-86 was used in Flow Cytometry to show that ERCC6L2 contributes to non-homologous end joining (NHEJ), and it may exert this function through interactions with SFPQ.
Tue Aug 25 00:00:00 EDT 2020
TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.
The FEBS journal
Schoeler K,Aufschnaiter A,Messner S,Derudder E,Herzog S,Villunger A,Rajewsky K,Labi V
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection.
International journal of molecular sciences
Li Q,Liu C,Yue R,El-Ashram S,Wang J,He X,Zhao D,Zhou X,Xu L
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in Flow Cytometry
Tue Feb 19 00:00:00 EST 2019
Effect of immune tolerance induced by immature dendritic cells and CTLA4-Ig on systemic lupus erythematosus: An in vivo study.
Experimental and therapeutic medicine
Huang C,Zhang L,Ling F,Wen S,Luo Y,Liu H,Liu J,Zheng W,Liang M,Sun J,Lin YK
11-0402-82 was used in Flow Cytometry to suggest that combined treatment with IL-10-DCs and CTLA4-Ig may be a promising novel therapeutic strategy for the treatment of SLE.
Thu Mar 01 00:00:00 EST 2018
Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function.
European journal of immunology
Karim AF,Reba SM,Li Q,Boom WH,Rojas RE
11-0402 was used in Flow cytometry/Cell sorting to study the role of T-cell expressed TLR2 on CD4+ T-cell differentiation and function.
Fri Sep 01 00:00:00 EDT 2017
Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB.
Nature communications
Willis SN,Tellier J,Liao Y,Trezise S,Light A,O'Donnell K,Garrett-Sinha LA,Shi W,Tarlinton DM,Nutt SL
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in Flow Cytometry
Fri Nov 10 00:00:00 EST 2017
Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells.
Scientific reports
Wang H,Lin J,Zeng L,Ouyang C,Ran P,Yang P,Liu Z
Thu Aug 17 00:00:00 EDT 2017
Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model.
Scientific reports
Wang H,Mo L,Xiao X,An S,Liu X,Ba J,Wu W,Ran P,Yang P,Liu Z
11-0402 was used in an ELISA assay to demonstrate that Pplase is not a dustmite allergen but can enhance allergic responses.
Mon Feb 27 00:00:00 EST 2017
Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A4 analog: Protective mechanisms and long-term effects on neurological recovery.
Brain and behavior
Hawkins KE,DeMars KM,Alexander JC,de Leon LG,Pacheco SC,Graves C,Yang C,McCrea AO,Frankowski JC,Garrett TJ,Febo M,Candelario-Jalil E
11-0402 was used in Flow cytometry/Cell sorting to identify the endogenous lipoxin A4 pathway as a promising therapeutic target for the treatment of ischaemic stroke.
Mon May 01 00:00:00 EDT 2017
Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
American journal of translational research
Wang H,Hu W,Liang Z,Zeng L,Li J,Yan H,Yang P,Liu Z,Wang L
11-0402 was used in Flow cytometry/Cell sorting to study how thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells.
Thu Oct 01 00:00:00 EDT 2020
Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development.
Scientific reports
Frodermann V,van Duijn J,van Pel M,van Santbrink PJ,Bot I,Kuiper J,de Jager SC
11-0402 was used in Flow cytometry/Cell sorting to study how MSC treatment affects not only inflammatory responses but also significantly reduces dyslipidaemia in mice.
Thu Oct 22 00:00:00 EDT 2015
Can dendritic cells improve whole cancer cell vaccines based on immunogenically killed cancer cells?
Oncoimmunology
Cicchelero L,Denies S,Devriendt B,de Rooster H,Sanders NN
11-0402 was used in Flow cytometry/Cell sorting to study whether dendritic cells can improve whole cancer cell vaccines.
Tue Dec 01 00:00:00 EST 2015
Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4).
The Journal of biological chemistry
Tsuji R,Koizumi H,Aoki D,Watanabe Y,Sugihara Y,Matsushita Y,Fukushima K,Fujiwara D
11-0402 was used in Flow cytometry/Cell sorting to investigate the role of lignin-rich enzyme lignin in dendritic cells.
Fri Feb 13 00:00:00 EST 2015
Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1.
Immunobiology
Donius LR,Orlando CM,Weis JJ,Weis JH
11-0402 was used in Flow cytometry/Cell sorting to study how the Cr2KO mouse provides a new model system for the analysis of Cr1 and Cr2 functions in the immune response of the mouse.
Wed Jan 01 00:00:00 EST 2014
Cancer immunotherapy employing an innovative strategy to enhance CD4+ T cell help in the tumor microenvironment.
PloS one
Song L,Yang MC,Knoff J,Wu TC,Hung CF
11-0402 was used in Flow cytometry/Cell sorting to investigate the effect of intratumoral injection of PADRE and the adjuvant CpG into HPV16 E7-expressing TC-1 tumours following cisplatin chemotherapy, showing potent antitumor effects and antigen-specific cell-mediated immune response.
Tue Dec 15 00:00:00 EST 2015
Synergic silencing of costimulatory molecules prevents cardiac allograft rejection.
Journal of translational medicine
Zhang X,Liu Y,Zhang G,Shi J,Zhang X,Zheng X,Jiang AT,Zhang ZX,Johnston N,Siu KS,Chen R,Lian D,Koos D,Quan D,Min WP
11-0402 was used in Flow cytometry/Cell sorting to demonstrate that the simultaneous silencing of CD40 and CD80 prevents allograft rejection.
Thu May 22 00:00:00 EDT 2014
Adrenergic β2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro.
PloS one
Nijhuis LE,Olivier BJ,Dhawan S,Hilbers FW,Boon L,Wolkers MC,Samsom JN,de Jonge WJ
11-0402 was used in Flow cytometry/Cell sorting to provide evidence that the adrenergic, rather than cholinergic, receptor activation on bone marrow derived DCs results in enhanced endocytosis uptake, enhanced IL-10 production but a decreased IL-6, IL-12p70 and IL-23 production.
Wed Dec 03 00:00:00 EST 2014
Co-culture of the 55-6 B cell hybridoma with the EL-4 thymoma cell. Effect on cell growth and monoclonal antibody production.
Cytotechnology
Martín-López A,Acosta-López L,García-Camacho F,Contreras-Gómez A,Molina-Grima E
11-0402 was used in Flow cytometry/Cell sorting to investigate the effect of different initial ratios when co-culturing the 55-6 hybridoma cells with the murine thymoma cell line EL-4.
Thu Aug 01 00:00:00 EDT 2013
DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.
BMC genomics
Innes CL,Hesse JE,Palii SS,Helmink BA,Holub AJ,Sleckman BP,Paules RS
Published figure using CD40 monoclonal antibody (Product # 11-0402-82) in Flow Cytometry
Tue Mar 12 00:00:00 EDT 2013
TRAF binding is required for a distinct subset of in vivo B cell functions of the oncoprotein LMP1.
Journal of immunology (Baltimore, Md. : 1950)
Arcipowski KM,Bishop GA
11-0402 was used in an ELISA assay to investigate whether the mechanism of action of TRAF proteins for LMP1 in vivo functions requires direct association.
Sat Dec 01 00:00:00 EST 2012
Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice.
PloS one
Kamphuis T,Meijerhof T,Stegmann T,Lederhofer J,Wilschut J,de Haan A
11-0402 was used in Flow cytometry/Cell sorting to assess the efficacy of a novel respiratory syncytial virus vaccine in mice.
Wed Sep 19 00:00:00 EDT 2012
Japanese encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells.
Virology journal
Cao S,Li Y,Ye J,Yang X,Chen L,Liu X,Chen H
11-0402 was used in Flow cytometry/Cell sorting to show that JEV severely infects and alters the phenotype of murine DCs to increase Tregs, and indicate a possible cause of immunosuppression in JIE.
Wed Jan 26 00:00:00 EST 2011
Inhibition of B-cell activation by retinal pigment epithelium.
Investigative ophthalmology & visual science
Sugita S,Horie S,Yamada Y,Mochizuki M
11-0402 was used in Flow cytometry/Cell sorting to determine whether retinal pigment epithelial (RPE) cells can inhibit B-cell activation in vitro, showing that B-cell proliferation was suppressed.
Mon Nov 01 00:00:00 EDT 2010
Cell-cell cooperation at the T helper cell/mast cell immunological synapse.
Blood
Gaudenzio N,Espagnolle N,Mars LT,Liblau R,Valitutti S,Espinosa E
11-0402 was used in Flow cytometry/Cell sorting to investigate whether cognate interactions between mast cells and class II-restricted CD4(+) T cells occur.
Thu Dec 03 00:00:00 EST 2009
Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses.
Journal of immunology (Baltimore, Md. : 1950)
Walsh KP,Brady MT,Finlay CM,Boon L,Mills KH
11-0402 was used in Flow cytometry/Cell sorting to provide evidence that parasites can exert bystander immunosuppression of pathogenic T cells that mediate autoimmune diseases.
Sat Aug 01 00:00:00 EDT 2009
Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70.
Journal of immunology (Baltimore, Md. : 1950)
Zietara N,Łyszkiewicz M,Gekara N,Puchałka J,Dos Santos VA,Hunt CR,Pandita TK,Lienenklaus S,Weiss S
11-0402 was used in Flow cytometry/Cell sorting to investigate the role of low level production of IFN, showing that its absence impairs antigen presentation capacity of splenic dendritic cells.
Wed Jul 15 00:00:00 EDT 2009
Polymeric linear Peptide chimeric vaccine-induced antimalaria immunity is associated with enhanced in vitro antigen loading.
Infection and immunity
Silva-Flannery LM,Cabrera-Mora M,Dickherber M,Moreno A
11-0402 was used in Flow cytometry/Cell sorting to investigate the antigenic properties of polymeric antimalarial peptides, showing that immunity is associated with enhanced in vitro antigen loading.
Fri May 01 00:00:00 EDT 2009
The effect of Helicobacter hepaticus infection on immune responses specific to herpes simplex virus type 1 and characteristics of dendritic cells.
Comparative medicine
Gulani J,Norbury CC,Bonneau RH,Beckwith CS
11-0402 was used in Flow cytometry/Cell sorting to indicate that Helicobacter hepaticus infection can influence the results of immunologic assays in mice.
Tue Dec 01 00:00:00 EST 2009
Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
The Journal of biological chemistry
Turner JD,Langley RS,Johnston KL,Gentil K,Ford L,Wu B,Graham M,Sharpley F,Slatko B,Pearlman E,Taylor MJ
11-0402 was used in Flow cytometry/Cell sorting to investigate the role of Wolbachia lipoprotein in pathogenesis of filariasis, showing that it stimulates innate and adaptive immunity through Toll-like receptors 2 and 6.
Fri Aug 14 00:00:00 EDT 2009
CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease.
Nature immunology
Hadeiba H,Sato T,Habtezion A,Oderup C,Pan J,Butcher EC
11-0402 was used in Flow cytometry/Cell sorting to identify a highly immunosuppressive population of pDCs present in lymphoid tissues.
Sat Nov 01 00:00:00 EDT 2008
Nitric oxide is a key component in inflammation-accelerated tumorigenesis.
Cancer research
Hussain SP,He P,Subleski J,Hofseth LJ,Trivers GE,Mechanic L,Hofseth AB,Bernard M,Schwank J,Nguyen G,Mathe E,Djurickovic D,Haines D,Weiss J,Back T,Gruys E,Laubach VE,Wiltrout RH,Harris CC
11-0402 was used in Flow cytometry/Cell sorting to test the hypothesis that an inflammatory microenvironment with an enhanced level of nitric oxide accelerates spontaneous tumour development (tumorigenesis).
Mon Sep 01 00:00:00 EDT 2008
Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS.
Glia
de Haas AH,Boddeke HW,Biber K
11-0402 was used in Flow cytometry/Cell sorting to evaluate the existence of distinct microglia phenotypes in various regions of the healthy, adult mouse central nervous system.
Sun Jun 01 00:00:00 EDT 2008
