Product References
Soluble NKG2D ligands impair CD8+ T cell antitumor function dependent of NKG2D downregulation in neuroblastoma.
Oncology letters
Zhang Y,Luo F,Dong K
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2023
Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab.
Signal transduction and targeted therapy
Zheng G,Guo Z,Li W,Xi W,Zuo B,Zhang R,Wen W,Yang AG,Jia L
11-1079-42 was used in Flow Cytometry to investigate if the nonclassical histocompatibility antigen HLA-G desensitizes breast cancer cells to trastuzumab by binding to the natural killer (NK) cell receptor KIR2DL4.
Wed Jun 23 00:00:00 EDT 2021
Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab.
Signal transduction and targeted therapy
Zheng G,Guo Z,Li W,Xi W,Zuo B,Zhang R,Wen W,Yang AG,Jia L
11-1079-42 was used in Flow Cytometry to investigate if the nonclassical histocompatibility antigen HLA-G desensitizes breast cancer cells to trastuzumab by binding to the natural killer (NK) cell receptor KIR2DL4.
Wed Jun 23 00:00:00 EDT 2021
Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy.
Cell death and differentiation
Humbert M,Seiler K,Mosimann S,Rentsch V,Sharma K,Pandey AV,McKenna SL,Tschan MP
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunocytochemistry
Sun Aug 01 00:00:00 EDT 2021
Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death.
Journal of cell science
Hope JM,Bersi MR,Dombroski JA,Clinch AB,Pereles RS,Merryman WD,King MR
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Mon Feb 22 00:00:00 EST 2021
Exosomes in serum‑free cultures of THP‑1 macrophages infected with Mycobacterium tuberculosis.
Molecular medicine reports
Biadglegne F,Rademacher P,De Sulbaran YGJ,König B,Rodloff AC,Zedler U,Dorhoi A,Sack U
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Western Blot
Mon Nov 01 00:00:00 EDT 2021
Analysis of the intracellular traffic of IgG in the context of Down syndrome (trisomy 21).
Scientific reports
Cejas RB,Tamaño-Blanco M,Blanco JG
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunocytochemistry
Wed May 26 00:00:00 EDT 2021
Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells.
Scientific reports
Silva JAF,Qi X,Grant MB,Boulton ME
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunocytochemistry
Mon Aug 30 00:00:00 EDT 2021
Multiple Immunostainings with Different Epitope Retrievals-The FOLGAS Protocol.
International journal of molecular sciences
von Schoenfeld A,Bronsert P,Poc M,Fuller A,Filby A,Kraft S,Kurowski K,Sörensen K,Huber J,Pfeiffer J,Proietti M,Stehl V,Werner M,Seidl M
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunohistochemistry
Sat Dec 25 00:00:00 EST 2021
Erlotinib Promotes Ligand-Induced EGFR Degradation in 3D but Not 2D Cultures of Pancreatic Ductal Adenocarcinoma Cells.
Cancers
Betriu N,Andreeva A,Semino CE
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunocytochemistry
Tue Sep 07 00:00:00 EDT 2021
CD7-deleted hematopoietic stem cells can restore immunity after CAR T cell therapy.
JCI insight
Kim MY,Cooper ML,Jacobs MT,Ritchey JK,Hollaway J,Fehniger TA,DiPersio JF
11-1079-42 was used in Flow Cytometry to support the development of CD7-KO HSCs to augment host immunity in patients with T cell malignancies after UCART7 treatment.
Mon Aug 23 00:00:00 EDT 2021
HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.
PLoS pathogens
Sant S,Quiñones-Parra SM,Koutsakos M,Grant EJ,Loudovaris T,Mannering SI,Crowe J,van de Sandt CE,Rimmelzwaan GF,Rossjohn J,Gras S,Loh L,Nguyen THO,Kedzierska K
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Phenotypic and Functional Changes in Peripheral Blood Natural Killer Cells in Crohn Disease Patients.
Mediators of inflammation
Samarani S,Sagala P,Jantchou P,Grimard G,Faure C,Deslandres C,Amre DK,Ahmad A
11-1079-42 was used in Flow Cytometry to investigate activation status, cytotoxic potential, and gut homing ability of the peripheral blood Natural Killer (NK) cells in Crohn disease (CD) patients.
Fri Dec 11 00:00:00 EST 2020
MAVS Genetic Variation Is Associated with Decreased HIV-1 Replication In Vitro and Reduced CD4+ T Cell Infection in HIV-1-Infected Individuals.
Viruses
Stunnenberg M,van Pul L,Sprokholt JK,van Dort KA,Gringhuis SI,Geijtenbeek TBH,Kootstra NA
11-1079 was used in Flow cytometry/Cell sorting to study the underlying mechanisms involved in the control of viral replication in individuals homozygous for this MAVS genotype.
Thu Jul 16 00:00:00 EDT 2020
MAVS Genetic Variation Is Associated with Decreased HIV-1 Replication In Vitro and Reduced CD4+ T Cell Infection in HIV-1-Infected Individuals.
Viruses
Stunnenberg M,van Pul L,Sprokholt JK,van Dort KA,Gringhuis SI,Geijtenbeek TBH,Kootstra NA
11-1079 was used in Flow cytometry/Cell sorting to study the underlying mechanisms involved in the control of viral replication in individuals homozygous for this MAVS genotype.
Thu Jul 16 00:00:00 EDT 2020
PBRM1 and the glycosylphosphatidylinositol biosynthetic pathway promote tumor killing mediated by MHC-unrestricted cytotoxic lymphocytes.
Science advances
Menasche BL,Davis EM,Wang S,Ouyang Y,Li S,Yu H,Shen J
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Highly Variable Sialylation Status of Donor-Specific Antibodies Does Not Impact Humoral Rejection Outcomes.
Frontiers in immunology
Barba T,Harb J,Ducreux S,Koenig A,Mathias V,Rabeyrin M,Pouliquen E,Sicard A,Chartoire D,Dugast E,Defrance T,Morelon E,Brouard S,Dubois V,Thaunat O
11-1079 was used in Flow cytometry/Cell sorting to conclude that DSA sialylation status is highly variable but has not impact on DSA pathogenicity and AMR outcome.
Wed Sep 02 00:00:00 EDT 2020
HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition.
Nature medicine
Vaccari M,Fourati S,Gordon SN,Brown DR,Bissa M,Schifanella L,Silva de Castro I,Doster MN,Galli V,Omsland M,Fujikawa D,Gorini G,Liyanage NPM,Trinh HV,McKinnon KM,Foulds KE,Keele BF,Roederer M,Koup RA,Shen X,Tomaras GD,Wong MP,Munoz KJ,Gach JS,Forthal DN,Montefiori DC,Venzon DJ,Felber BK,Rosati M,Pavlakis GN,Rao M,Sekaly RP,Franchini G
11-1079 was used in Flow cytometry/Cell sorting to examine the ability of several vaccine prime modalities together with two ALVAC-SIV + gp120 protein boosts to reduce the risk of SIVmac251 acquisition in Rhesus macaques.
Fri Jun 01 00:00:00 EDT 2018
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
Oncotarget
Sponaas AM,Yang R,Rustad EH,Standal T,Thoresen AS,Dao Vo C,Waage A,Slørdahl TS,Børset M,Sundan A
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Fri Aug 10 00:00:00 EDT 2018
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.
Nature communications
Arbore G,West EE,Rahman J,Le Friec G,Niyonzima N,Pirooznia M,Tunc I,Pavlidis P,Powell N,Li Y,Liu P,Servais A,Couzi L,Fremeaux-Bacchi V,Placais L,Ferraro A,Walsh PR,Kavanagh D,Afzali B,Lavender P,Lachmann HJ,Kemper C
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Wed Oct 10 00:00:00 EDT 2018
Guidelines for the use of flow cytometry and cell sorting in immunological studies.
European journal of immunology
Cossarizza A,Chang HD,Radbruch A,Akdis M,Andrä I,Annunziato F,Bacher P,Barnaba V,Battistini L,Bauer WM,Baumgart S,Becher B,Beisker W,Berek C,Blanco A,Borsellino G,Boulais PE,Brinkman RR,Büscher M,Busch DH,Bushnell TP,Cao X,Cavani A,Chattopadhyay PK,Cheng Q,Chow S,Clerici M,Cooke A,Cosma A,Cosmi L,Cumano A,Dang VD,Davies D,De Biasi S,Del Zotto G,Della Bella S,Dellabona P,Deniz G,Dessing M,Diefenbach A,Di Santo J,Dieli F,Dolf A,Donnenberg VS,Dörner T,Ehrhardt GRA,Endl E,Engel P,Engelhardt B,Esser C,Everts B,Dreher A,Falk CS,Fehniger TA,Filby A,Fillatreau S,Follo M,Förster I,Foster J,Foulds GA,Frenette PS,Galbraith D,Garbi N,García-Godoy MD,Geginat J,Ghoreschi K,Gibellini L,Goettlinger C,Goodyear CS,Gori A,Grogan J,Gross M,Grützkau A,Grummitt D,Hahn J,Hammer Q,Hauser AE,Haviland DL,Hedley D,Herrera G,Herrmann M,Hiepe F,Holland T,Hombrink P,Houston JP,Hoyer BF,Huang B,Hunter CA,Iannone A,Jäck HM,Jávega B,Jonjic S,Juelke K,Jung S,Kaiser T,Kalina T,Keller B,Khan S,Kienhöfer D,Kroneis T,Kunkel D,Kurts C,Kvistborg P,Lannigan J,Lantz O,Larbi A,LeibundGut-Landmann S,Leipold MD,Levings MK,Litwin V,Liu Y,Lohoff M,Lombardi G,Lopez L,Lovett-Racke A,Lubberts E,Ludewig B,Lugli E,Maecker HT,Martrus G,Matarese G,Maueröder C,McGrath M,McInnes I,Mei HE,Melchers F,Melzer S,Mielenz D,Mills K,Mirrer D,Mjösberg J,Moore J,Moran B,Moretta A,Moretta L,Mosmann TR,Müller S,Müller W,Münz C,Multhoff G,Munoz LE,Murphy KM,Nakayama T,Nasi M,Neudörfl C,Nolan J,Nourshargh S,O'Connor JE,Ouyang W,Oxenius A,Palankar R,Panse I,Peterson P,Peth C,Petriz J,Philips D,Pickl W,Piconese S,Pinti M,Pockley AG,Podolska MJ,Pucillo C,Quataert SA,Radstake TRDJ,Rajwa B,Rebhahn JA,Recktenwald D,Remmerswaal EBM,Rezvani K,Rico LG,Robinson JP,Romagnani C,Rubartelli A,Ruckert B,Ruland J,Sakaguchi S,Sala-de-Oyanguren F,Samstag Y,Sanderson S,Sawitzki B,Scheffold A,Schiemann M,Schildberg F,Schimisky E,Schmid SA,Schmitt S,Schober K,Schüler T,Schulz AR,Schumacher T,Scotta C,Shankey TV,Shemer A,Simon AK,Spidlen J,Stall AM,Stark R,Stehle C,Stein M,Steinmetz T,Stockinger H,Takahama Y,Tarnok A,Tian Z,Toldi G,Tornack J,Traggiai E,Trotter J,Ulrich H,van der Braber M,van Lier RAW,Veldhoen M,Vento-Asturias S,Vieira P,Voehringer D,Volk HD,von Volkmann K,Waisman A,Walker R,Ward MD,Warnatz K,Warth S,Watson JV,Watzl C,Wegener L,Wiedemann A,Wienands J,Willimsky G,Wing J,Wurst P,Yu L,Yue A,Zhang Q,Zhao Y,Ziegler S,Zimmermann J
11-1079 was used in Flow cytometry/Cell sorting to collect the currently accepted best methods for monitoring most of the variation of the major players of immune system.
Sun Oct 01 00:00:00 EDT 2017
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
Nature medicine
Vaccari M,Gordon SN,Fourati S,Schifanella L,Liyanage NP,Cameron M,Keele BF,Shen X,Tomaras GD,Billings E,Rao M,Chung AW,Dowell KG,Bailey-Kellogg C,Brown EP,Ackerman ME,Vargas-Inchaustegui DA,Whitney S,Doster MN,Binello N,Pegu P,Montefiori DC,Foulds K,Quinn DS,Donaldson M,Liang F,Loré K,Roederer M,Koup RA,McDermott A,Ma ZM,Miller CJ,Phan TB,Forthal DN,Blackburn M,Caccuri F,Bissa M,Ferrari G,Kalyanaraman V,Ferrari MG,Thompson D,Robert-Guroff M,Ratto-Kim S,Kim JH,Michael NL,Phogat S,Barnett SW,Tartaglia J,Venzon D,Stablein DM,Alter G,Sekaly RP,Franchini G
11-1079 was used in Flow cytometry/Cell sorting to assess the efficacy of a recombinant Aventis Pasteur's canarypox vector-SIV and gp120 alum vaccine at delaying the onset of SIVmac251 in rhesus macaques.
Fri Jul 01 00:00:00 EDT 2016
Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.
The Journal of clinical investigation
Kim SM,Roy SG,Chen B,Nguyen TM,McMonigle RJ,McCracken AN,Zhang Y,Kofuji S,Hou J,Selwan E,Finicle BT,Nguyen TT,Ravi A,Ramirez MU,Wiher T,Guenther GG,Kono M,Sasaki AT,Weisman LS,Potma EO,Tromberg BJ,Edwards RA,Hanessian S,Edinger AL
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunofluorescence
Tue Nov 01 00:00:00 EDT 2016
Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells.
Cell death & disease
Tan KP,Ho MY,Cho HC,Yu J,Hung JT,Yu AL
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunofluorescence
Thu Aug 25 00:00:00 EDT 2016
T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma.
Oncoimmunology
Singh N,Kulikovskaya I,Barrett DM,Binder-Scholl G,Jakobsen B,Martinez D,Pawel B,June CH,Kalos MD,Grupp SA
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes.
Traffic (Copenhagen, Denmark)
Dieckmann NM,Hackmann Y,Aricò M,Griffiths GM
Published figure using CD107a (LAMP-1) monoclonal antibody (Product # 11-1079-42) in Immunofluorescence
Tue Dec 01 00:00:00 EST 2015
NK cell immunesenescence is increased by psychological but not physical stress in older adults associated with raised cortisol and reduced perforin expression.
Age (Dordrecht, Netherlands)
Duggal NA,Upton J,Phillips AC,Hampson P,Lord JM
11-1079 was used in Flow cytometry/Cell sorting to assess the effect of the physical stress of hip fracture and the psychological stress of depression on NK cell cytotoxicity in an aged immune system.
Sun Feb 01 00:00:00 EST 2015
The immunodominant influenza A virus M158-66 cytotoxic T lymphocyte epitope exhibits degenerate class I major histocompatibility complex restriction in humans.
Journal of virology
Choo JA,Liu J,Toh X,Grotenbreg GM,Ren EC
11-1079 was used in Immunofluorescence to demonstrate that the same influenza A virus peptide can be presented by both HLA-A and HLA-C molecules.
Mon Sep 01 00:00:00 EDT 2014
The combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus.
Journal of immunology (Baltimore, Md. : 1950)
Lim DS,Yawata N,Selva KJ,Li N,Tsai CY,Yeong LH,Liong KH,Ooi EE,Chong MK,Ng ML,Leo YS,Yawata M,Wong SB
11-1079 was used in Flow cytometry/Cell sorting to investigate the response of NK cells against dengue-infected cells, showing that a combination of type I IFN, TNF-α, and cell surface receptor engagement with dendritic cells is required.
Sat Nov 15 00:00:00 EST 2014
Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America
Weiskopf D,Angelo MA,de Azeredo EL,Sidney J,Greenbaum JA,Fernando AN,Broadwater A,Kolla RV,De Silva AD,de Silva AM,Mattia KA,Doranz BJ,Grey HM,Shresta S,Peters B,Sette A
11-1079 was used in Flow cytometry/Cell sorting to analyse dengue virus-specific responses, supporting an HLA-linked protective role for CD8+ T cells.
Tue May 28 00:00:00 EDT 2013
A Novel Method Linking Antigen Presentation by Human Monocyte-Derived Macrophages to CD8(+) T Cell Polyfunctionality.
Frontiers in immunology
Short KR,Grant EJ,Vissers M,Reading PC,Diavatopoulos DA,Kedzierska K
11-1079 was used in Flow cytometry/Cell sorting to study how virally infected macrophages impact T cell function.
Fri Dec 06 00:00:00 EST 2013
CD8(+) granzyme B(+)-mediated tissue injury vs. CD4(+)IFNγ(+)-mediated parasite killing in human cutaneous leishmaniasis.
The Journal of investigative dermatology
Santos Cda S,Boaventura V,Ribeiro Cardoso C,Tavares N,Lordelo MJ,Noronha A,Costa J,Borges VM,de Oliveira CI,Van Weyenbergh J,Barral A,Barral-Netto M,Brodskyn CI
11-1079 was used in Flow cytometry/Cell sorting to reveal a dichotomy in human CL: CD8(+) granzyme B(+)T-cells mediate tissue injury, whereas CD4(+)IFN-g(+)T-cells mediate parasite killing.
Sat Jun 01 00:00:00 EDT 2013
In vivo blockade of the programmed cell death-1 pathway using soluble recombinant PD-1-Fc enhances CD4+ and CD8+ T cell responses but has limited clinical benefit.
Journal of immunology (Baltimore, Md. : 1950)
Amancha PK,Hong JJ,Rogers K,Ansari AA,Villinger F
11-1079 was used in Flow cytometry/Cell sorting to evaluate the effect of soluble rPD-1-Fc treatment as an alternative strategy to block PD-1 ligands in Rhesus macaques.
Sun Dec 15 00:00:00 EST 2013
Cytotoxic response persists in subjects treated for tuberculosis decades ago.
BMC infectious diseases
Savolainen LE,Koskivirta P,Kantele A,Valleala H,Pusa L,Tuompo R,Westerlund-Wikström B,Tuuminen T
11-1079 was used in Flow cytometry/Cell sorting to evaluate the influence of various anti-TB therapeutic schemes on the immunological profiles of residual cytotoxic T lymphocytes.
Thu Dec 05 00:00:00 EST 2013
Interleukin 15 primes natural killer cells to kill via NKG2D and cPLA2 and this pathway is active in psoriatic arthritis.
PloS one
Tang F,Sally B,Ciszewski C,Abadie V,Curran SA,Groh V,Fitzgerald O,Winchester RJ,Jabri B
11-1079 was used in Flow cytometry/Cell sorting to discern the involvement of interleukin 15 in priming NK cells and discover where this pathway is active.
Fri Jul 18 00:00:00 EDT 2014