Product References
Targeted suppression of Dpt-specific B cells in humanized Rag2- γc- mouse model of HDM allergy.
Scandinavian journal of immunology
Ralchev NR,Kerekov N,Mihaylova N,Kremlitzka M,Hristova D,Dzhorev J,Erdei A,Tchorbanov AI
12-0088-42 was used in Flow cytometry/Cell sorting to investigate Derp1 in dust mite allergies.
Wed Feb 01 00:00:00 EST 2023
Serum amyloid a, C-reactive protein, and procalcitonin levels in children with Mycoplasma pneumoniae infection.
Journal of clinical laboratory analysis
Jiang Y,Wang W,Zhang Z,Ma X,Sang Y,Wang J,Xu G,Feng Q,Zhao S
12-0088-42 was used in T-Cell Activation to show that SAA, CRP, and PCT were specific markers for diagnosing early MP infection in children.
Tue Mar 01 00:00:00 EST 2022
Screening of an individualized treatment strategy for an advanced gallbladder cancer using patient-derived tumor xenograft and organoid models.
Frontiers in oncology
Tan D,An J,Gong M,Wang H,Li H,Meng H,Zhang C,Zhao Y,Ge X,Shi C
12-0088-42 was used in Flow cytometry/Cell sorting to indicate that the combined use of PDO and PDX models can guide the clinical treatment course for gallbladder cancer patients to achieve individualized and effective treatment.
Tue Jan 03 00:00:00 EST 2023
Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes.
Nature communications
Renner K,Schwittay T,Chaabane S,Gottschling J,Müller C,Tiefenböck C,Salewski JN,Winter F,Buchtler S,Balam S,Malfertheiner MV,Lubnow M,Lunz D,Graf B,Hitzenbichler F,Hanses F,Poeck H,Kreutz M,Orsó E,Burkhardt R,Niedermair T,Brochhausen C,Gessner A,Salzberger B,Mack M
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Fri May 21 00:00:00 EDT 2021
Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma.
Oncotarget
Vardam-Kaur T,Pathangey LB,McCormick DJ,Bergsagel PL,Cohen PA,Gendler SJ
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Tue Sep 28 00:00:00 EDT 2021
Human endoglin-CD3 bispecific T cell engager antibody induces anti-tumor effect in vivo.
Theranostics
Zhong L,Shi W,Gan L,Liu X,Huo Y,Wu P,Zhang Z,Wu T,Peng H,Huang Y,Zhao Y,Yuan Y,Deng Z,Tang H
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Wed Jul 28 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
12-0088-42 was used in Flow Cytometry to show the feasibility and efficacy of human MUC16 ectodomain- specific BiTEDs and provide a basis for the combination with anti-VEGF therapy for ovarian cancer.
Thu Oct 21 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
12-0088-42 was used in Flow Cytometry to show the feasibility and efficacy of human MUC16 ectodomain- specific BiTEDs and provide a basis for the combination with anti-VEGF therapy for ovarian cancer.
Thu Oct 21 00:00:00 EDT 2021
Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning.
Proceedings of the National Academy of Sciences of the United States of America
Nesterenko PA,McLaughlin J,Cheng D,Bangayan NJ,Burton Sojo G,Seet CS,Qin Y,Mao Z,Obusan MB,Phillips JW,Witte ON
12-0088-42 was used in Flow cytometry/Cell sorting to describe the use of mRNA sequencing via cross-linker regulated intracellular phenotype (CLInt-Seq) for efficient recovery of antigen-specific TCRs in cells stained for combinations of intracellular proteins such as cytokines or transcription factors.
Tue Jan 19 00:00:00 EST 2021
Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation.
Molecular therapy. Nucleic acids
Festag J,Thelemann T,Schell M,Raith S,Michel S,Jaschinski F,Klar R
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Fri Sep 04 00:00:00 EDT 2020
Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation.
Oncogenesis
Zhang CX,Huang DJ,Baloche V,Zhang L,Xu JX,Li BW,Zhao XR,He J,Mai HQ,Chen QY,Zhang XS,Busson P,Cui J,Li J
12-0088 was used in Flow cytometry/Cell sorting to report that Gal-9 expression in nasopharyngeal carcinoma (NPC) cells enhances the generation of MDreport that Gal-9 expression in nasopharyngeal carcinoma (NPC) cells enhances the generation of MDSCs (CD33+CD11b+HLA-DR-) from CD33+ bystander cells. SCs (CD33+CD11b+HLA-DR-) from CD33+ bystander cells.
Mon Jul 06 00:00:00 EDT 2020
A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.
Molecular therapy oncolytics
Hammill JA,Kwiecien JM,Dvorkin-Gheva A,Lau VWC,Baker C,Wu Y,Bezverbnaya K,Aarts C,Heslen CW,Denisova GF,Derocher H,Milne K,Nelson BH,Bramson JL
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Fri Jun 26 00:00:00 EDT 2020
Elucidation of Pelareorep Pharmacodynamics in A Phase I Trial in Patients with KRAS-Mutated Colorectal Cancer.
Molecular cancer therapeutics
Goel S,Ocean AJ,Parakrama RY,Ghalib MH,Chaudhary I,Shah U,Viswanathan S,Kharkwal H,Coffey M,Maitra R
12-0088 was used in Flow cytometry/Cell sorting to show that Pelareorep leads to a clear recurrent immune stimulatory response with cytotoxic T-cell activation, and homes and replicates in patients with KRAS-mutated colorectal cancer.
Fri May 01 00:00:00 EDT 2020
Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis.
Cancers
Darvekar S,Juzenas P,Oksvold M,Kleinauskas A,Holien T,Christensen E,Stokke T,Sioud M,Peng Q
12-0088-42 was used in Flow Cytometry to explore the possibility of targeting activated human blood T cells ex vivo, using the concept of photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA), a precursor of an endogenously synthesized photosensitizer protoporphyrin IX (PpIX) in combination with blue light.
Thu Feb 06 00:00:00 EST 2020
Immune characterization of metastatic colorectal cancer patients post reovirus administration.
BMC cancer
Parakrama R,Fogel E,Chandy C,Augustine T,Coffey M,Tesfa L,Goel S,Maitra R
12-0088 was used in Flow cytometry/Cell sorting to evaluate the nature of immune response by determining the cytokine expression pattern in peripheral circulation along with the distribution of antigen presenting cells (APCs) and activated T lymphocytes.
Thu Jun 18 00:00:00 EDT 2020
T Cell Receptor Engineered Lymphocytes for Cancer Therapy.
Current protocols in immunology
Rollins MR,Spartz EJ,Stromnes IM
12-0088-42 was used in Flow Cytometry to synthesize and expand upon methodologies to generate, isolate, and engineer human T cells with tumor-reactive TCRs for adoptive cell therapy.
Mon Jun 01 00:00:00 EDT 2020
STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion.
Cell death and differentiation
Zhang CX,Ye SB,Ni JJ,Cai TT,Liu YN,Huang DJ,Mai HQ,Chen QY,He J,Zhang XS,Zeng YX,Li J,Cui J
12-0088-42 was used in Flow Cytometry to investigate the role of stimulator of interferon genes (STING) in regulation of myeloid-derived suppressor cell differentiation and antitumor immunity in Epstein-Barr virus-associated nasopharyngeal carcinomas.
Fri Nov 01 00:00:00 EDT 2019
Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells.
Stem cells and development
Fujii S,Yoshida S,Inagaki E,Hatou S,Tsubota K,Takahashi M,Shimmura S,Sugita S
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo.
PloS one
Petrovic K,Robinson J,Whitworth K,Jinks E,Shaaban A,Lee SP
12-0088-42 was used in Flow Cytometry to find that the CAR-T-cells demonstrated clear TEM8-specific cytotoxic and cytokine release responses in vitro, but when injected into healthy C57BL6 and NSG mice they rapidly and selectively disappeared from the circulation and in most cases caused rapid toxicity.
Tue Mar 17 00:00:00 EDT 2020
Lower High-Density Lipoproteins Levels During Human Immunodeficiency Virus Type 1 Infection Are Associated With Increased Inflammatory Markers and Disease Progression.
Frontiers in immunology
Marín-Palma D,Castro GA,Cardona-Arias JA,Urcuqui-Inchima S,Hernandez JC
12-0088 was used in Flow cytometry/Cell sorting to indicate that HDL might modulate the expression of several key components of the inflammasomes during HIV-1 infection, suggesting a novel role of HDL in modifying the inflammatory state and consequently, the progression of HIV-1 infection.
Mon Mar 21 00:00:00 EDT 2022
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
Oncotarget
Sponaas AM,Yang R,Rustad EH,Standal T,Thoresen AS,Dao Vo C,Waage A,Slørdahl TS,Børset M,Sundan A
12-0088 was used in Flow cytometry to study the expression of PD-1 on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
Fri Aug 10 00:00:00 EDT 2018
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models.
Stem cell reports
Sugita S,Makabe K,Fujii S,Iwasaki Y,Kamao H,Shiina T,Ogasawara K,Takahashi M
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Tue Nov 14 00:00:00 EST 2017
Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.
PLoS pathogens
Miles B,Miller SM,Folkvord JM,Levy DN,Rakasz EG,Skinner PJ,Connick E
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Sat Oct 01 00:00:00 EDT 2016
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Journal of immunology (Baltimore, Md. : 1950)
Younis RH,Han KL,Webb TJ
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2016
Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria.
Stem cells international
Chen J,Wang Q,Feng X,Zhang Z,Geng L,Xu T,Wang D,Sun L
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade.
Molecular medicine reports
Tang ZS,Hao YH,Zhang EJ,Xu CL,Zhou Y,Zheng X,Yang DL
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
Liposomal Glutathione Supplementation Restores TH1 Cytokine Response to Mycobacterium tuberculosis Infection in HIV-Infected Individuals.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Ly J,Lagman M,Saing T,Singh MK,Tudela EV,Morris D,Anderson J,Daliva J,Ochoa C,Patel N,Pearce D,Venketaraman V
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2015
Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.
Nature communications
Miles B,Miller SM,Folkvord JM,Kimball A,Chamanian M,Meditz AL,Arends T,McCarter MD,Levy DN,Rakasz EG,Skinner PJ,Connick E
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2015
RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.
Nature communications
Jozwik A,Habibi MS,Paras A,Zhu J,Guvenel A,Dhariwal J,Almond M,Wong EHC,Sykes A,Maybeno M,Del Rosario J,Trujillo-Torralbo MB,Mallia P,Sidney J,Peters B,Kon OM,Sette A,Johnston SL,Openshaw PJ,Chiu C
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Mon Dec 21 00:00:00 EST 2015
Investigating the causes for decreased levels of glutathione in individuals with type II diabetes.
PloS one
Lagman M,Ly J,Saing T,Kaur Singh M,Vera Tudela E,Morris D,Chi PT,Ochoa C,Sathananthan A,Venketaraman V
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Wed Dec 30 00:00:00 EST 2015
Immune response to JC virus T antigen in patients with and without colorectal neoplasia.
Gut microbes
Butcher LD,Garcia M,Arnold M,Ueno H,Goel A,Boland CR
12-0088 was used in Flow cytometry/Cell sorting to compare the immune response to JC virus T antigen in those with and without colorectal neoplasia.
Tue Jul 01 00:00:00 EDT 2014
CD4+CD25(high), CD8+CD28- cells and thyroid autoantibodies in breast cancer patients.
Central-European journal of immunology
Biylgi O,Karagöz B,Türken O,Gültepe M,Özgün A,Tunçel T,Emirzeoğlu L,Çelik S,Müftüoğlu T,Gökhan Kandemir E
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Thu Jul 09 00:00:00 EDT 2015
Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma.
Oncotarget
Ye SB,Li ZL,Luo DH,Huang BJ,Chen YS,Zhang XS,Cui J,Zeng YX,Li J
12-0088 was used in Flow cytometry/Cell sorting to show that tumour-derived exosomes promote tumour progression and T-cell dysfunction through regulation of exosomal microRNAs in human carcinomas.
Wed Jul 30 00:00:00 EDT 2014
Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C.
Journal of viral hepatitis
Yanagisawa K,Yue S,van der Vliet HJ,Wang R,Alatrakchi N,Golden-Mason L,Schuppan D,Koziel MJ,Rosen HR,Exley MA
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2013
A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia.
Blood
Gorska MM,Alam R
12-0088 was used in Flow cytometry/Cell sorting to show that the V22G mutation of Unc119 represents a novel genetic defect in ICL.
Thu Feb 09 00:00:00 EST 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy.
PloS one
Presicce P,Orsborn K,King E,Pratt J,Fichtenbaum CJ,Chougnet CA
12-0088 was used in Flow cytometry/Cell sorting to analyse Treg frequency and phenotype in 11 HIV-infected individuals enrolled in a single, prospective clinical trial.
Fri Jul 20 00:00:00 EDT 2012
Sepsis-induced human lymphocyte apoptosis and cytokine production in "humanized" mice.
Journal of leukocyte biology
Unsinger J,McDonough JS,Shultz LD,Ferguson TA,Hotchkiss RS
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2009
B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity.
Retrovirology
Brudek T,Christensen T,Aagaard L,Petersen T,Hansen HJ,Møller-Larsen A
Published figure using CD8a monoclonal antibody (Product # 12-0088-42) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2009
Expression and function of PDCD1 at the human maternal-fetal interface.
Biology of reproduction
Taglauer ES,Trikhacheva AS,Slusser JG,Petroff MG
12-0088 was used in Flow cytometry/Cell sorting to examine whether human maternal T cells express PDCD1.
Mon Sep 01 00:00:00 EDT 2008
The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.
Immunity
Jones RG,Bui T,White C,Madesh M,Krawczyk CM,Lindsten T,Hawkins BJ,Kubek S,Frauwirth KA,Wang YL,Conway SJ,Roderick HL,Bootman MD,Shen H,Foskett JK,Thompson CB
12-0088 was used in Flow cytometry/Cell sorting to establish the role of Bax and Bak in viable T cell function.
Wed Aug 01 00:00:00 EDT 2007
