Product References
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity.
NPJ vaccines
Hendin HE,Lavoie PO,Gravett JM,Pillet S,Saxena P,Landry N,D'Aoust MA,Ward BJ
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Mon Apr 11 00:00:00 EDT 2022
Methotrexate-loaded nanoparticles ameliorate experimental model of autoimmune arthritis by regulating the balance of interleukin-17-producing T cells and regulatory T cells.
Journal of translational medicine
Park JS,Lee D,Yang S,Jeong HY,Na HS,Cho KH,Choi J,Koo H,Cho ML,Park SH
12-0951-81 was used in Flow Cytometry to study the efficacy of methotrexate-loaded nanoparticles against experimental model of rheumatoid arthritis.
Fri Feb 11 00:00:00 EST 2022
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway.
Scientific reports
Kim HJ,Kim YJ,Park W
12-0951-81 was used in Flow Cytometry to show that berberine has anti-inflammatory properties related to its inhibition of NO, PGE2, Fas, GM-CSF, LIF, LIX, RANTES, and MIP-2 in dsRNA-induced macrophages via the endoplasmic reticulum stress-related calcium-.
Fri May 28 00:00:00 EDT 2021
Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway.
Scientific reports
Kim HJ,Kim YJ,Park W
12-0951-81 was used in Flow Cytometry to show that berberine has anti-inflammatory properties related to its inhibition of NO, PGE2, Fas, GM-CSF, LIF, LIX, RANTES, and MIP-2 in dsRNA-induced macrophages via the endoplasmic reticulum stress-related calcium-.
Fri May 28 00:00:00 EDT 2021
Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation.
Cell reports
Qi T,Sun M,Zhang C,Chen P,Xiao C,Chang X
12-0951 was used in Flow cytometry/Cell sorting to show that ascorbic acid (vitamin C), an essential nutrient, is able to promote plasma cell differentiation and humoral immune response by enhancing TET2/3-mediated DNA demethylation.
Tue Dec 01 00:00:00 EST 2020
The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy.
Cellular & molecular immunology
Moschovakis GL,Bubke A,Friedrichsen M,Ristenpart J,Back JW,Falk CS,Kremmer E,Förster R
12-0951-81 was used in Flow Cytometry to demonstrate that CCR7 signaling is essential for the induction of CIA and identify CCR7 as a potential therapeutic target in RA.
Tue Oct 01 00:00:00 EDT 2019
A Recombinant Rabies Virus Expressing Fms-like Tyrosine Kinase 3 Ligand (Flt3L) Induces Enhanced Immunogenicity in Mice.
Virologica Sinica
Zhang Y,Yang J,Li M,Cui M,Fu ZF,Zhao L,Zhou M
12-0951 was used in Flow cytometry/Cell sorting to extend the potential of Flt3L as a good adjuvant to develop novel rabies vaccine by enhancing the VNA production through activating the DC-TFH-GC B axis in immunized mice.
Sun Dec 01 00:00:00 EST 2019
Cyclooxygenase-1 Regulates the Development of Follicular Th Cells via Prostaglandin E2.
Journal of immunology (Baltimore, Md. : 1950)
Liu T,Yang Q,Cao YJ,Yuan WM,Lei AH,Zhou P,Zhou W,Liu YD,Shi MH,Yang Q,Tang JY,Wang HK,Zhang H,Yu Y,Zhou J
12-0951-81 was used in Flow Cytometry to indicate that COX-1 plays an important role in the development of TFH cells.
Thu Aug 15 00:00:00 EDT 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Human herpesvirus-encoded kinase induces B cell lymphomas in vivo.
The Journal of clinical investigation
Anders PM,Montgomery ND,Montgomery SA,Bhatt AP,Dittmer DP,Damania B
12-0951 was used in Flow cytometry/Cell sorting to analyse the function of viral protein kinase in vivo.
Fri Jun 01 00:00:00 EDT 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells.
Cell reports
Kenderes KJ,Levack RC,Papillion AM,Cabrera-Martinez B,Dishaw LM,Winslow GM
12-0951 was used in Flow cytometry/Cell sorting to propose that T-bet+ IgM memory cells can differentiate into any effector B cell lineage to provide long-term multifunctional immunity.
Tue Jul 24 00:00:00 EDT 2018
Clonal Evolution of Autoreactive Germinal Centers.
Cell
Degn SE,van der Poel CE,Firl DJ,Ayoglu B,Al Qureshah FA,Bajic G,Mesin L,Reynaud CA,Weill JC,Utz PJ,Victora GD,Carroll MC
12-0951 was used in Flow cytometry/Cell sorting to study the maturation of the self-reactive B cell response, contextualising the epitope spreading observed in autoimmune disease.
Thu Aug 24 00:00:00 EDT 2017
The IgM receptor FcμR limits tonic BCR signaling by regulating expression of the IgM BCR.
Nature immunology
Nguyen TT,Kläsener K,Zürn C,Castillo PA,Brust-Mascher I,Imai DM,Bevins CL,Reardon C,Reth M,Baumgarth N
12-0951 was used in Flow cytometry/Cell sorting to study the expression and role of FcμR in the trans-Golgi network of developing B cells.
Wed Mar 01 00:00:00 EST 2017
A Novel Rabies Vaccine Expressing CXCL13 Enhances Humoral Immunity by Recruiting both T Follicular Helper and Germinal Center B Cells.
Journal of virology
Wang Z,Li M,Zhou M,Zhang Y,Yang J,Cao Y,Wang K,Cui M,Chen H,Fu ZF,Zhao L
12-0951-81 was used in Functional assay to provide a better understanding of the role of CXCL13 in RABV-induced immune responses which will help in designing more efficacious rabies vaccines.
Wed Feb 01 00:00:00 EST 2017
Regulation of endothelial Fas expression as a mechanism of promotion of vascular integrity by mural cells in tumors.
Cancer science
Kamei R,Tanaka HY,Kawano T,Morii C,Tanaka S,Nishihara H,Iwata C,Kano MR
12-0951 was used in Flow cytometry/Cell sorting to explore the relationship between endothelial Fas expression, mural cells and vascular integrity in tumour angiogenesis.
Mon May 01 00:00:00 EDT 2017
Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.
Journal of immunology (Baltimore, Md. : 1950)
Tang H,Wang H,Lin Q,Fan F,Zhang F,Peng X,Fang X,Liu J,Ouyang K
12-0951 was used in Flow cytometry/Cell sorting to determine the function of 1,4,5-trisphosphate receptor-mediated Ca2+ release in B cells.
Sat Jul 15 00:00:00 EDT 2017
Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.
Scientific reports
Yeku OO,Purdon TJ,Koneru M,Spriggs D,Brentjens RJ
Tue Sep 05 00:00:00 EDT 2017
YY1 plays an essential role at all stages of B-cell differentiation.
Proceedings of the National Academy of Sciences of the United States of America
Kleiman E,Jia H,Loguercio S,Su AI,Feeney AJ
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Tue Jul 05 00:00:00 EDT 2016
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Nature medicine
Ortega-Molina A,Boss IW,Canela A,Pan H,Jiang Y,Zhao C,Jiang M,Hu D,Agirre X,Niesvizky I,Lee JE,Chen HT,Ennishi D,Scott DW,Mottok A,Hother C,Liu S,Cao XJ,Tam W,Shaknovich R,Garcia BA,Gascoyne RD,Ge K,Shilatifard A,Elemento O,Nussenzweig A,Melnick AM,Wendel HG
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2015
Substituting threonine 187 with alanine in p27Kip1 prevents pituitary tumorigenesis by two-hit loss of Rb1 and enhances humoral immunity in old age.
The Journal of biological chemistry
Zhao H,Bauzon F,Bi E,Yu JJ,Fu H,Lu Z,Cui J,Jeon H,Zang X,Ye BH,Zhu L
Fri Feb 27 00:00:00 EST 2015
Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells.
PloS one
Kim YU,Lim H,Jung HE,Wetsel RA,Chung Y
12-0951 was used in Flow cytometry/Cell sorting to demonstrate that Tfh cells rather than Th17 cells contribute to the autoimmune germinal center reactions in BXD2 mice.
Fri Jan 29 00:00:00 EST 2016
Interleukin-21 promotes germinal center reaction by skewing the follicular regulatory T cell to follicular helper T cell balance in autoimmune BXD2 mice.
Arthritis & rheumatology (Hoboken, N.J.)
Ding Y,Li J,Yang P,Luo B,Wu Q,Zajac AJ,Wildner O,Hsu HC,Mountz JD
12-0951 was used in Flow cytometry/Cell sorting to indicate that high levels of IL-21 selectively enhance Tfh cell differentiation but inhibit Tfr cell commitment and the suppressive function of Tfr cells on Tfh cells and B cells.
Mon Sep 01 00:00:00 EDT 2014
Coinfection with Streptococcus pneumoniae modulates the B cell response to influenza virus.
Journal of virology
Wolf AI,Strauman MC,Mozdzanowska K,Whittle JR,Williams KL,Sharpe AH,Weiser JN,Caton AJ,Hensley SE,Erikson J
12-0951 was used in Flow cytometry/Cell sorting to demonstrate how co-infection of S. pneumoniae and influenza virus may affect the generation of protective antiviral antibodies.
Wed Oct 01 00:00:00 EDT 2014
Cancer immunotherapy employing an innovative strategy to enhance CD4+ T cell help in the tumor microenvironment.
PloS one
Song L,Yang MC,Knoff J,Wu TC,Hung CF
12-0951 was used in Flow cytometry/Cell sorting to investigate the effect of intratumoral injection of PADRE and the adjuvant CpG into HPV16 E7-expressing TC-1 tumours following cisplatin chemotherapy, showing potent antitumor effects and antigen-specific cell-mediated immune response.
Tue Dec 15 00:00:00 EST 2015
IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells.
Journal of immunology (Baltimore, Md. : 1950)
Ding Y,Li J,Wu Q,Yang P,Luo B,Xie S,Druey KM,Zajac AJ,Hsu HC,Mountz JD
12-0951 was used in Flow cytometry/Cell sorting to investigate the role of germinal centres in autoimmunity, showing that IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells.
Thu Aug 15 00:00:00 EDT 2013
Up-regulated expression of miR-23a/b targeted the pro-apoptotic Fas in radiation-induced thymic lymphoma.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Li B,Sun M,Gao F,Liu W,Yang Y,Liu H,Cheng Y,Liu C,Cai J
12-0951 was used in Flow cytometry/Cell sorting to demonstrate that the expression of miR-23a/b is up-regulated in radiation-induced thymic lymphoma.
Fri Aug 29 00:00:00 EDT 2014
The mismatch repair pathway functions normally at a non-AID target in germinal center B cells.
Blood
Green B,Belcheva A,Nepal RM,Boulianne B,Martin A
12-0951-81 was used in Flow cytometry/Cell sorting to investigate whether mismatch repair corrects mutations in germinal center B cells at a gene that is not mutated by AID.
Thu Sep 15 00:00:00 EDT 2011
B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice.
The Journal of clinical investigation
Wang YH,Diamond B
12-0951 was used in Flow cytometry/Cell sorting to suggest that tolerance occurs post-activation in B cells and that B cell receptor revision regulates autoreactivity generated during an immune response.
Fri Aug 01 00:00:00 EDT 2008
Characterization of fibroblasts responsible for cartilage destruction in arthritis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Treese C,Mittag A,Lange F,Tarnok A,Loesche A,Emmrich F,Lehmann J,Sack U
12-0951 was used in Flow cytometry/Cell sorting to show that LS48 is an excellent tool to gain a deeper understanding of synovial fibroblasts in rheumatoid arthritis.
Tue Apr 01 00:00:00 EDT 2008
Up-regulation of Fas (CD95) expression in tumour cells in vivo.
Immunology
Peshes-Yaloz N,Rosen D,Sondel PM,Krammer PH,Berke G
Published figure using CD95 (APO-1/Fas) monoclonal antibody (Product # 12-0951-81) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2007