Product References
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Nature communications
Xiao X,Shi J,He C,Bu X,Sun Y,Gao M,Xiang B,Xiong W,Dai P,Mao Q,Xing X,Yao Y,Yu H,Xu G,Li S,Ren Y,Chen B,Jiang C,Meng G,Lee YR,Wei W,Freeman GJ,Xie C,Zhang J
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Fri May 19 00:00:00 EDT 2023
Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling.
Journal of experimental & clinical cancer research : CR
Zheng Y,Wang N,Wang S,Zhang J,Yang B,Wang Z
17-8898-82 was used in Flow cytometry/Cell sorting to investigate the impact of chronic psychological stress on breast cancer growth, metastasis, and pre-metastatic niche (PMN) formation.
Sat May 20 00:00:00 EDT 2023
Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy.
Cancer research communications
Zhu Z,Tang R,Huff S,Kummetha IR,Wang L,Li N,Rana TM
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2023
Histone methyltransferase WHSC1 loss dampens MHC-I antigen presentation pathway to impair IFN-γ-stimulated antitumor immunity.
The Journal of clinical investigation
Ren J,Li N,Pei S,Lian Y,Li L,Peng Y,Liu Q,Guo J,Wang X,Han Y,Zhang G,Wang H,Li Y,Jiang J,Li Q,Tan M,Peng J,Hu G,Xiao Y,Li X,Lin M,Qin J
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Fri Apr 15 00:00:00 EDT 2022
Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease.
The Journal of clinical investigation
Yang K,Han J,Asada M,Gill JG,Park JY,Sathe MN,Gattineni J,Wright T,Wysocki CA,de la Morena MT,Garza LA,Yan N
17-8898-82 was used in Flow Cytometry to propose SKIV2L-associated trichohepatoenteric syndrome (THES) as a new mTORopathy for which sirolimus may be a promising therapy.
Tue Jan 18 00:00:00 EST 2022
Wnt5A Signaling Blocks Progression of Experimental Visceral Leishmaniasis.
Frontiers in immunology
Maity S,Chakraborty A,Mahata SK,Roy S,Das AK,Sen M
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Mar 22 00:00:00 EDT 2022
Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment.
Frontiers in immunology
Wong SW,McCarroll J,Hsu K,Geczy CL,Tedla N
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Mon Jun 06 00:00:00 EDT 2022
eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma.
Journal for immunotherapy of cancer
Chen X,Wang K,Jiang S,Sun H,Che X,Zhang M,He J,Wen Y,Liao M,Li X,Zhou X,Song J,Ren X,Yi W,Yang J,Chen X,Yin M,Cheng Y
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer.
The Journal of clinical investigation
Deng P,Wang Z,Chen J,Liu S,Yao X,Liu S,Liu L,Yu Z,Huang Y,Xiong Z,Xiao R,Gao J,Liang W,Chen J,Liu H,Hong JH,Chan JY,Guan P,Chen J,Wang Y,Yin J,Li J,Zheng M,Zhang C,Zhou P,Kang T,Teh BT,Yu Q,Zuo Z,Jiang Q,Liu J,Xiong Y,Xia X,Tan J
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Mon Dec 12 00:00:00 EST 2022
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Cell reports
Wang W,Wu S,Cen Z,Zhang Y,Chen Y,Huang Y,Cillo AR,Prokopec JS,Quarato G,Vignali DAA,Stewart-Ornstein J,Li S,Lu B,Gong YN
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice.
Nature communications
Chandana M,Anand A,Ghosh S,Das R,Beura S,Jena S,Suryawanshi AR,Padmanaban G,Nagaraj VA
17-8898-82 was used in Flow cytometry/Cell sorting to show heme synthesized in asexual stages promotes cerebral pathogenesis by enhancing hemozoin formation.
Tue Jul 12 00:00:00 EDT 2022
Immunosuppressive Myeloid Cells Induce Nitric Oxide-Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells.
Cancer immunology research
Cartwright ANR,Suo S,Badrinath S,Kumar S,Melms J,Luoma A,Bagati A,Saadatpour A,Izar B,Yuan GC,Wucherpfennig KW
17-8898-82 was used in Flow Cytometry to demonstrate that MDSCs do not block early steps of T-cell activation but rather induce DNA damage and p53 pathway activation in CD8+ T cells through an iNOS-dependent pathway.
Thu Apr 01 00:00:00 EDT 2021
Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function.
Cell reports
Daneshmandi S,Cassel T,Lin P,Higashi RM,Wulf GM,Boussiotis VA,Fan TW,Seth P
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Mar 09 00:00:00 EST 2021
Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy.
Cell reports
Dodagatta-Marri E,Ma HY,Liang B,Li J,Meyer DS,Chen SY,Sun KH,Ren X,Zivak B,Rosenblum MD,Headley MB,Pinzas L,Reed NI,Del Cid JS,Hann BC,Yang S,Giddabasappa A,Noorbehesht K,Yang B,Dal Porto J,Tsukui T,Niessen K,Atakilit A,Akhurst RJ,Sheppard D
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Jul 06 00:00:00 EDT 2021
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Cell communication and signaling : CCS
Li J,Wang S,Wang N,Zheng Y,Yang B,Wang X,Zhang J,Pan B,Wang Z
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Mon Aug 30 00:00:00 EDT 2021
Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8+ T Cells and Macrophages.
International journal of nanomedicine
Luo ZW,Xia K,Liu YW,Liu JH,Rao SS,Hu XK,Chen CY,Xu R,Wang ZX,Xie H
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Jun 01 00:00:00 EDT 2021
Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection.
iScience
Steele L,Mannion AJ,Shaw G,Maclennan KA,Cook GP,Rudd CE,Taylor A
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Fri Jun 25 00:00:00 EDT 2021
Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer.
Cellular and molecular gastroenterology and hepatology
Liu JL,Wang CY,Cheng TY,Rixiati Y,Ji C,Deng M,Yao S,Yuan LH,Zhao YY,Shen T,Li JM
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Knockout of immunotherapy prognostic marker genes eliminates the effect of the anti-PD-1 treatment.
NPJ precision oncology
Yang N,Ji F,Cheng L,Lu J,Sun X,Lin X,Lan X
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Fri May 07 00:00:00 EDT 2021
G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of Plasmodium berghei Infection.
Frontiers in immunology
Yi H,Jiang W,Yang F,Li F,Li Y,Zhu W,Li Q,Fakhar SH,Cao Y,Luo L,Zhang W,He Y
17-8898-82 was used in Flow cytometry/Cell sorting to analyze the pathological progression of experimental cerebral malaria and acute liver injury in mice with different G6pd activity infected with P.berghei.
Fri Dec 17 00:00:00 EST 2021
Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion.
Immunity
Wu J,Dobbs N,Yang K,Yan N
17-8898-82 was used in Flow Cytometry to investigate if mammalian stimulator of interferon genes possesses widespread IFN-independent activities that are important for restricting HSV-1 infection, tumor immune evasion and likely also adaptive immunity.
Tue Jul 14 00:00:00 EDT 2020
Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis.
Scientific reports
Utz B,Turpin R,Lampe J,Pouwels J,Klefström J
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Fri Oct 30 00:00:00 EDT 2020
Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy.
Biomedicines
Ebelt ND,Zuniga E,Marzagalli M,Zamloot V,Blazar BR,Salgia R,Manuel ER
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.
PloS one
Parra M,Weitner M,Yang A,Akue A,Liu X,Schmidt T,Allman WR,Akkoyunlu M,Derrick SC
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
MAIT cells contribute to protection against lethal influenza infection in vivo.
Nature communications
van Wilgenburg B,Loh L,Chen Z,Pediongco TJ,Wang H,Shi M,Zhao Z,Koutsakos M,Nüssing S,Sant S,Wang Z,D'Souza C,Jia X,Almeida CF,Kostenko L,Eckle SBG,Meehan BS,Kallies A,Godfrey DI,Reading PC,Corbett AJ,McCluskey J,Klenerman P,Kedzierska K,Hinks TSC
Published figure using Granzyme B monoclonal antibody (Product # 17-8898-82) in Flow Cytometry
Fri Nov 09 00:00:00 EST 2018