Product References
Interleukin-1β secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair.
Gut microbes
Wu WH,Kim M,Chang LC,Assie A,Saldana-Morales FB,Zegarra-Ruiz DF,Norwood K,Samuel BS,Diehl GE
25-5825-82 was used in Flow cytometry/Cell sorting to demonstrate an unexpected role for commensal bacteria in promoting IL-1β secretion to support intestinal barrier repair.
Thu Feb 24 00:00:00 EST 2022
Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection.
eLife
Silverstein NJ,Wang Y,Manickas-Hill Z,Carbone C,Dauphin A,Boribong BP,Loiselle M,Davis J,Leonard MM,Kuri-Cervantes L,Meyer NJ,Betts MR,Li JZ,Walker BD,Yu XG,Yonker LM,Luban J
25-5825-82 was used in Flow cytometry/Cell sorting to suggest that, by promoting disease tolerance, homeostatic ILCs decrease morbidity and mortality associated with SARS-CoV-2 infection, and that lower ILC abundance contributes to increased COVID-19 severity with age and in males.
Fri Mar 11 00:00:00 EST 2022
ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation.
Cellular & molecular immunology
Liu Y,Bockermann R,Hadi M,Safari I,Carrion B,Kveiborg M,Issazadeh-Navikas S
25-5825-82 was used in Flow Cytometry to study the role of ADAM12 in T-cell responses, fate determination on activation, and its functions in T cells to mediate tissue inflammation.
Sun Aug 01 00:00:00 EDT 2021
DNA Methylation Patterns in T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Exposed to an Aryl Hydrocarbon Receptor Ligand.
Environmental health perspectives
Burke CG,Myers JR,Post CM,Boulé LA,Lawrence BP
25-5825-82 was used in Flow Cytometry to identify cellular mechanisms that drive impaired CD4+ T-cell responses later in life following maternal exposure to an exogenous aryl hydrocarbon receptor. ligand.
Fri Jan 01 00:00:00 EST 2021
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Nature communications
Zhao Z,Wang H,Shi M,Zhu T,Pediongco T,Lim XY,Meehan BS,Nelson AG,Fairlie DP,Mak JYW,Eckle SBG,de Lima Moreira M,Tumpach C,Bramhall M,Williams CG,Lee HJ,Haque A,Evrard M,Rossjohn J,McCluskey J,Corbett AJ,Chen Z
25-5825-82 was used in Flow Cytometry to highlight the potential utility of targeting MAIT cells to combat a range of bacterial pathogens.
Fri Jul 16 00:00:00 EDT 2021
In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection.
mBio
Clemmensen HS,Dube JY,McIntosh F,Rosenkrands I,Jungersen G,Aagaard C,Andersen P,Behr MA,Mortensen R
25-5825-82 was used in Flow cytometry/Cell sorting to demonstrate that immunization with such antigens can counteract this phenomenon by maintaining antigen-specific T cells in a state of low differentiation.
Tue Apr 20 00:00:00 EDT 2021
Culture, expansion, and flow-cytometry-based functional analysis of pteropid bat MR1-restricted unconventional T cells.
STAR protocols
Sia WR,Hey YY,Foo R,Wang LF,Leeansyah E
25-5825 was used in Flow cytometry/Cell sorting to examine pteropid MR1T cell functionality, including proliferative capacity, cytotoxicity, and cytokine production.
Fri Jun 18 00:00:00 EDT 2021
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Cell
Lee JY,Hall JA,Kroehling L,Wu L,Najar T,Nguyen HH,Lin WY,Yeung ST,Silva HM,Li D,Hine A,Loke P,Hudesman D,Martin JC,Kenigsberg E,Merad M,Khanna KM,Littman DR
25-5825 was used in Flow cytometry/Cell sorting to suggest that serum amyloid A proteins direct a pathogenic pro-inflammatory Th17 cell differentiation program and promote Th17-mediated inflammatory diseases.
Thu Jan 09 00:00:00 EST 2020
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy.
Cell
Wu L,Hollinshead KER,Hao Y,Au C,Kroehling L,Ng C,Lin WY,Li D,Silva HM,Shin J,Lafaille JJ,Possemato R,Pacold ME,Papagiannakopoulos T,Kimmelman AC,Satija R,Littman DR
25-5825-82 was used in Flow Cytometry to suggest that inhibiting glycolysis by targeting Gpi1 could be an effective therapeutic strategy with minimum toxicity for Th17-mediated autoimmune diseases, and, more generally, that metabolic redundancies can be exploited for selective targeting of disease processes.
Thu Aug 06 00:00:00 EDT 2020
Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids.
Cell
Hong JY,Lim J,Carvalho F,Cho JY,Vaidyanathan B,Yu S,Annicelli C,Ip WKE,Medzhitov R
25-5825 was used in Flow cytometry/Cell sorting to demonstrate that perinatal stress can have long-term consequences on CD8 T cell immunity by altering HPA axis activity.
Thu Mar 05 00:00:00 EST 2020
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
25-5825 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 EDT 2020
PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kwon M,Kim CG,Lee H,Cho H,Kim Y,Lee EC,Choi SJ,Park J,Seo IH,Bogen B,Song IC,Jo DY,Kim JS,Park SH,Choi I,Choi YS,Shin EC
25-5825-82 was used in Flow Cytometry to indicate that combined blockade of PD-1 and TGFβ may be useful for the treatment of multiple myeloma.
Wed Apr 01 00:00:00 EDT 2020
MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation.
Allergy, asthma & immunology research
Wang Z,Ji N,Chen Z,Sun Z,Wu C,Yu W,Hu F,Huang M,Zhang M
25-5825 was used in Flow cytometry/Cell sorting to investigate the associations between Th2 differentiation and miR-1165b-3p in asthma as well as the possible mechanisms.
Tue Sep 01 00:00:00 EDT 2020
The Identity of Human Tissue-Emigrant CD8+ T Cells.
Cell
Buggert M,Vella LA,Nguyen S,Wu VH,Chen Z,Sekine T,Perez-Potti A,Maldini CR,Manne S,Darko S,Ransier A,Kuri-Cervantes L,Japp AS,Brody IB,Ivarsson MA,Gorin JB,Rivera-Ballesteros O,Hertwig L,Antel JP,Johnson ME,Okoye A,Picker L,Vahedi G,Sparrelid E,Llewellyn-Lacey S,Gostick E,Sandberg JK,Björkström N,Bar-Or A,Dori Y,Naji A,Canaday DH,Laufer TM,Wells AD,Price DA,Frank I,Douek DC,Wherry EJ,Itkin MG,Betts MR
25-5825-82 was used in Flow cytometry/Cell sorting to employ an integrated approach to characterize tissue-emigrant lineages in thoracic duct lymph (TDL).
Wed Dec 23 00:00:00 EST 2020
Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection.
Cell reports
Alterauge D,Bagnoli JW,Dahlström F,Bradford BM,Mabbott NA,Buch T,Enard W,Baumjohann D
25-5825-82 was used in Flow Cytometry to evaluate the contributions of the CXCR5 receptor and Bcl6 transcription factor in maintaining T follicular helper cells and germinal centres.
Tue Oct 06 00:00:00 EDT 2020
Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells.
Nature communications
Lee M,Lee E,Han SK,Choi YH,Kwon DI,Choi H,Lee K,Park ES,Rha MS,Joo DJ,Shin EC,Kim S,Kim JK,Lee YJ
25-5825 was used in Flow cytometry/Cell sorting to indicate that innate T cells share effector differentiation processes in the thymus.
Mon Aug 31 00:00:00 EDT 2020
Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.
Cell reports
Yang YH,Istomine R,Alvarez F,Al-Aubodah TA,Shi XQ,Takano T,Thornton AM,Shevach EM,Zhang J,Piccirillo CA
25-5825-82 was used in Flow Cytometry to show that high salt (HS) drives thymic Treg cells to adopt a T helper type 17 (Th17)-like phenotype and enhances generation of Th17-like induced Treg cells in a SGK1-dependent manner, all the while maintaining suppressive function.
Tue Feb 04 00:00:00 EST 2020
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine.
Nature communications
Campesato LF,Budhu S,Tchaicha J,Weng CH,Gigoux M,Cohen IJ,Redmond D,Mangarin L,Pourpe S,Liu C,Zappasodi R,Zamarin D,Cavanaugh J,Castro AC,Manfredi MG,McGovern K,Merghoub T,Wolchok JD
25-5825 was used in Flow cytometry/Cell sorting to show that the AHR pathway is selectively active in IDO/TDO-overexpressing tumors and is associated with resistance to immune checkpoint inhibitors.
Tue Aug 11 00:00:00 EDT 2020
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
25-5825 was used in Flow cytometry/Cell sorting to suggest a revised model for ILC differentiation that redefines the cell-fate potential of helper-ILC-restricted Zbtb16+ ILCPs.
Tue Apr 16 00:00:00 EDT 2019
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer.
Cell stem cell
Zhu Y,Smith DJ,Zhou Y,Li YR,Yu J,Lee D,Wang YC,Di Biase S,Wang X,Hardoy C,Ku J,Tsao T,Lin LJ,Pham AT,Moon H,McLaughlin J,Cheng D,Hollis RP,Campo-Fernandez B,Urbinati F,Wei L,Pang L,Rezek V,Berent-Maoz B,Macabali MH,Gjertson D,Wang X,Galic Z,Kitchen SG,An DS,Hu-Lieskovan S,Kaplan-Lefko PJ,De Oliveira SN,Seet CS,Larson SM,Forman SJ,Heath JR,Zack JA,Crooks GM,Radu CG,Ribas A,Kohn DB,Witte ON,Yang L
25-5825 was used in Flow cytometry/Cell sorting to develop a proof-of-concept for hematopoietic stem cell-engineered iNKT (HSC-iNKT) cell therapy with the potential to provide therapeutic levels of iNKT cells for a patient's lifetime.
Thu Oct 03 00:00:00 EDT 2019
CD160 serves as a negative regulator of NKT cells in acute hepatic injury.
Nature communications
Kim TJ,Park G,Kim J,Lim SA,Kim J,Im K,Shin MH,Fu YX,Del Rio ML,Rodriguez-Barbosa JI,Yee C,Suh KS,Kim SJ,Ha SJ,Lee KM
25-5825-82 was used in Flow cytometry/Cell sorting to show that CD160 is not essential for NKT cell development.
Mon Jul 22 00:00:00 EDT 2019
Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection.
Cell reports
Anderson CK,Reilly EC,Lee AY,Brossay L
25-5825 was used in Flow cytometry/Cell sorting to study compensatory mechanisms in immune responses to viruses when classical T cell immunity has been evaded.
Tue Apr 09 00:00:00 EDT 2019
A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.
Nature communications
Myers LM,Tal MC,Torrez Dulgeroff LB,Carmody AB,Messer RJ,Gulati G,Yiu YY,Staron MM,Angel CL,Sinha R,Markovic M,Pham EA,Fram B,Ahmed A,Newman AM,Glenn JS,Davis MM,Kaech SM,Weissman IL,Hasenkrug KJ
25-5825-82 was used in Flow Cytometry to demonstrate that even during exhaustion there is a subset of functional CD8+ T cells defined by surface expression of SIRPα.
Fri Feb 15 00:00:00 EST 2019
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.
Nature communications
Scheer S,Ackloo S,Medina TS,Schapira M,Li F,Ward JA,Lewis AM,Northrop JP,Richardson PL,Kaniskan HÜ,Shen Y,Liu J,Smil D,McLeod D,Zepeda-Velazquez CA,Luo M,Jin J,Barsyte-Lovejoy D,Huber KVM,De Carvalho DD,Vedadi M,Zaph C,Brown PJ,Arrowsmith CH
25-5825 was used in Flow cytometry/Cell sorting to present a collection of chemical probes and associated reagents and data to elucidate the function of human and murine protein methyltransferases in cellular studies.
Thu Jan 03 00:00:00 EST 2019
Characterization and Purification of Mouse Mucosal-Associated Invariant T (MAIT) Cells.
Current protocols in immunology
Chen Z,Wang H,D'Souza C,Koay HF,Meehan B,Zhao Z,Pediongco T,Shi M,Zhu T,Wang B,Kjer-Nielsen L,Eckle SBG,Rossjohn J,Fairlie DP,Godfrey DI,Strugnell RA,McCluskey J,Corbett AJ
25-5825-82 was used in Flow cytometry/Cell sorting to provide a step-by-step protocol for mucosal-associated invariant T (MAIT) cell sorting and adoptive transfer.
Sun Dec 01 00:00:00 EST 2019
Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses.
Immunity
Kim M,Galan C,Hill AA,Wu WJ,Fehlner-Peach H,Song HW,Schady D,Bettini ML,Simpson KW,Longman RS,Littman DR,Diehl GE
25-5825 was used in Flow cytometry/Cell sorting to identify a cellular mechanism by which the microbiota limits intestinal inflammation and promotes tissue homeostasis.
Tue Jul 17 00:00:00 EDT 2018
Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Cancer cell
Zappasodi R,Budhu S,Hellmann MD,Postow MA,Senbabaoglu Y,Manne S,Gasmi B,Liu C,Zhong H,Li Y,Huang AC,Hirschhorn-Cymerman D,Panageas KS,Wherry EJ,Merghoub T,Wolchok JD
25-5825-82 was used in Flow Cytometry to provide evidence that mouse and human circulating and intra-tumor 4PD1hi inhibit T cell functions in a PD-1/PD-L1 dependent fashion and resemble follicular helper T cell (TFH)-like cells.
Mon Jun 11 00:00:00 EDT 2018
Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.
Immunity, inflammation and disease
Omodho B,Miao T,Symonds ALJ,Singh R,Li S,Wang P
25-5825 was used in Flow cytometry/Cell sorting to show that despite impaired proliferation and IL2 production, tolerant T cells can display inflammatory responses in response to antigen stimulation and this is controlled at least partly by Egr2 and 3.
Fri Jun 01 00:00:00 EDT 2018
Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8+ T Cell Immunity.
Frontiers in immunology
Araujo Furlan CL,Tosello Boari J,Rodriguez C,Canale FP,Fiocca Vernengo F,Boccardo S,Beccaria CG,Adoue V,Joffre O,Gruppi A,Montes CL,Acosta Rodriguez EV
25-5825 was used in Flow cytometry/Cell sorting to study the role of regulatory T cells during Trypanosoma cruzi infection.
Thu Sep 26 00:00:00 EDT 2019
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
25-5825 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathway.
Science translational medicine
Wen Z,Shen Y,Berry G,Shahram F,Li Y,Watanabe R,Liao YJ,Goronzy JJ,Weyand CM
25-5825 was used in Flow cytometry/Cell sorting to study the VEGF-Jagged1-Notch pathway and the effects of T cells in pathogenic large vessel vasculitis.
Wed Jul 19 00:00:00 EDT 2017
MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates.
Mucosal immunology
Greene JM,Dash P,Roy S,McMurtrey C,Awad W,Reed JS,Hammond KB,Abdulhaqq S,Wu HL,Burwitz BJ,Roth BF,Morrow DW,Ford JC,Xu G,Bae JY,Crank H,Legasse AW,Dang TH,Greenaway HY,Kurniawan M,Gold MC,Harriff MJ,Lewinsohn DA,Park BS,Axthelm MK,Stanton JJ,Hansen SG,Picker LJ,Venturi V,Hildebrand W,Thomas PG,Lewinsohn DM,Adams EJ,Sacha JB
25-5825 was used in Flow cytometry/Cell sorting to investigate the response of MR1 restricted mucosal-associated invariant T cells to mycobacterial vaccination and infection in nonhuman primates.
Mon May 01 00:00:00 EDT 2017
Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.
Mucosal immunology
Chen Z,Wang H,D'Souza C,Sun S,Kostenko L,Eckle SB,Meehan BS,Jackson DC,Strugnell RA,Cao H,Wang N,Fairlie DP,Liu L,Godfrey DI,Rossjohn J,McCluskey J,Corbett AJ
25-5825 was used in Flow cytometry/Cell sorting to investigate the mucosal-associated invariant T cell response in a model of bacterial lung infection.
Sun Jan 01 00:00:00 EST 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
25-5825 was used in Flow cytometry/Cell sorting to show that nonlymphoid compartments can serve as reservoirs for Th2 memory cells, and furthermore that innate effector function of Th2 memory cells is restricted to CD4⁺ memory T cells residing in the peritoneal cavity.
Wed Feb 01 00:00:00 EST 2017
mTORC2 regulates multiple aspects of NKT-cell development and function.
European journal of immunology
Sklarz T,Guan P,Gohil M,Cotton RM,Ge MQ,Haczku A,Das R,Jordan MS
25-5825 was used in Flow cytometry/Cell sorting to define the molecular pathway and role of Rictor in regulating invariant NKT-cell fate.
Wed Mar 01 00:00:00 EST 2017
A Mouse Model of West Nile Virus Infection.
Current protocols in mouse biology
Graham JB,Swarts JL,Lund JM
25-5825 was used in Flow cytometry/Cell sorting to develop a mouse model to study the breadth of symptoms and disease severity seen in human West Nile virus infection.
Wed Dec 20 00:00:00 EST 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
25-5825 was used in Flow cytometry/Cell sorting to highlight that intratumoral immunomodulation with an oncolytic virus expressing a rationally selected ligand can be an effective strategy to drive systemic efficacy of immune checkpoint blockade.
Mon Feb 13 00:00:00 EST 2017
Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
The Journal of allergy and clinical immunology
Mattoo H,Mahajan VS,Maehara T,Deshpande V,Della-Torre E,Wallace ZS,Kulikova M,Drijvers JM,Daccache J,Carruthers MN,Castelino FV,Stone JR,Stone JH,Pillai S
25-5825 was used in Flow cytometry/Cell sorting to characterise CD4(+) T-cell subsets in patients with IgG4-related disease based on clonal expansion and ability to enter affected tissue.
Thu Sep 01 00:00:00 EDT 2016
CD4(+) T-cell survival in the GI tract requires dectin-1 during fungal infection.
Mucosal immunology
Drummond RA,Dambuza IM,Vautier S,Taylor JA,Reid DM,Bain CC,Underhill DM,Masopust D,Kaplan DH,Brown GD
25-5825 was used in Flow cytometry/Cell sorting to study the role of Dectin-1 in the coordination of fungal-specific CD4(+) T-cell responses in the GI tract.
Tue Mar 01 00:00:00 EST 2016
Treatment with cyclophosphamide supported by various dendritic cell-based vaccines induces diversification in CD4⁺ T cell response against MC38 colon carcinoma.
International journal of oncology
Wojas-Turek J,Szczygieł A,Kicielińska J,Rossowska J,Piasecki E,Pajtasz-Piasecka E
25-5825 was used in Flow cytometry/Cell sorting to show that an application of cyclophosphamide supported by dendritic cell based vaccines affected differentiation of the activity of CD4+ T cell subpopulations accompanied by an alteration in CD8+ cell number.
Mon Feb 01 00:00:00 EST 2016
Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation.
Journal of immunology (Baltimore, Md. : 1950)
Cuff AO,Robertson FP,Stegmann KA,Pallett LJ,Maini MK,Davidson BR,Male V
25-5825 was used in Flow cytometry/Cell sorting to study the molecular signal that characterises an Eomeshi population of natural killer cells in the human liver that is not present in the blood.
Thu Dec 01 00:00:00 EST 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
25-5825 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 EDT 2016
Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner.
Biology of sex differences
Elderman M,van Beek A,Brandsma E,de Haan B,Savelkoul H,de Vos P,Faas M
25-5825 was used in Flow cytometry/Cell sorting to study sex differences in the intestinal and peripheral immune cell populations of two mouse strains with different susceptibility for developing colitis.
Thu Apr 07 00:00:00 EDT 2016
Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
Oncogene
De Simone V,Franzè E,Ronchetti G,Colantoni A,Fantini MC,Di Fusco D,Sica GS,Sileri P,MacDonald TT,Pallone F,Monteleone G,Stolfi C
25-5825 was used in Flow cytometry/Cell sorting to explore cotargeting of STAT3 and NF-kB as a novel approach to combat colorectal cancers.
Wed Jul 01 00:00:00 EDT 2015
Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23.
Mucosal immunology
Donaldson DS,Bradford BM,Artis D,Mabbott NA
25-5825 was used in Flow cytometry/Cell sorting to assess the relationship between microbiota in the colon and development of isolated lymphoid follicles.
Fri May 01 00:00:00 EDT 2015
Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses.
Toxicological sciences : an official journal of the Society of Toxicology
Marshall NB,Lukomska E,Long CM,Kashon ML,Sharpnack DD,Nayak AP,Anderson KL,Jean Meade B,Anderson SE
25-5825 was used in Flow cytometry/Cell sorting to examine the effects of dermal triclosan exposure on the skin and lymph nodes of mice and in a human skin model to identify mechanisms for augmenting allergic responses.
Tue Sep 01 00:00:00 EDT 2015
Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis.
PloS one
Kim WS,Kim JS,Cha SB,Han SJ,Kim H,Kwon KW,Kim SJ,Eum SY,Cho SN,Shin SJ
25-5825 was used in Flow cytometry/Cell sorting to compare the bacterial burden, inflammation and kinetics of immune cells during aerogenic infection in the lung between laboratory-adapted strains (Mtb H37Rv and H37Ra) and Mtb K strain.
Mon Jun 27 00:00:00 EDT 2016
MyD88 signaling in CD4 T cells promotes IFN-γ production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection.
Journal of immunology (Baltimore, Md. : 1950)
Zhang Y,Jones M,McCabe A,Winslow GM,Avram D,MacNamara KC
25-5825 was used in Flow cytometry/Cell sorting to investigate the signals that activate haematopoietic stem and progenitor cells during ehrlichiosis.
Wed May 01 00:00:00 EDT 2013
NK cell maturation and function in C57BL/6 mice are altered by caloric restriction.
Journal of immunology (Baltimore, Md. : 1950)
Clinthorne JF,Beli E,Duriancik DM,Gardner EM
25-5825 was used in Flow cytometry/Cell sorting to analyse of the effects of caloric intake on NK cell phenotype and function.
Tue Jan 15 00:00:00 EST 2013
Th17 effector cells support B cell responses outside of germinal centres.
PloS one
Patakas A,Benson RA,Withers DR,Conigliaro P,McInnes IB,Brewer JM,Garside P
25-5825 was used in Flow cytometry/Cell sorting to investigate the role of Th17 cells in the development of a humoral immune response using T and B cell receptor transgenic mice.
Thu Jun 20 00:00:00 EDT 2013
