Product References
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.
Cells
Azam Z,Sapra L,Baghel K,Sinha N,Gupta RK,Soni V,Saini C,Mishra PK,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jan 04 00:00:00 EST 2023
FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations.
Oncogene
Pawlikowska P,Delestré L,Gregoricchio S,Oppezzo A,Esposito M,Diop MB,Rosselli F,Guillouf C
45-0193-82 was used in Flow cytometry/Cell sorting to indicate that loss of the FANC pathway, known to control genetic instability, fosters the expansion of leukaemic cells carrying oncogenic mutations rather than mutation formation.
Fri Sep 01 00:00:00 EDT 2023
Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.
Investigative ophthalmology & visual science
Finburgh EN,Mauduit O,Noguchi T,Bu JJ,Abbas AA,Hakim DF,Bellusci S,Meech R,Makarenkova HP,Afshari NA
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
High-yield enrichment of mouse small intestine intraepithelial lymphocytes by immunomagnetic depletion of EpCAM+ cells.
STAR protocols
Prakhar P,Gonzalez V,Park JH
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Fri Mar 18 00:00:00 EDT 2022
Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells.
Immunity
Kim E,Paik D,Ramirez RN,Biggs DG,Park Y,Kwon HK,Choi GB,Huh JR
45-0193-82 was used in Flow cytometry/Cell sorting to investigate intestinal inflammation in children with autism spectrum disorders in response to maternal gut bacteria.
Tue Jan 11 00:00:00 EST 2022
P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice.
Frontiers in immunology
Schall N,Talamini L,Wilhelm M,Jouvin-Marche E,Muller S
45-0193-82 was used in Flow cytometry/Cell sorting to suggest that P140 belongs to a new family of non-immunosuppressive immunoregulators that do not correct T and B cell abnormalities but rather contribute to the clearance of deleterious T and B cells.
Tue Jun 21 00:00:00 EDT 2022
Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs).
Frontiers in immunology
Sapra L,Shokeen N,Porwal K,Saini C,Bhardwaj A,Mathew M,Mishra PK,Chattopadhyay N,Dar HY,Verma B,Srivastava RK
45-0193-82 was used in Enzyme-linked immunosorbent assay to establish a novel osteo-protective and immunomodulatory potential of BL in augmenting bone health under osteoporotic conditions.
Tue Jun 14 00:00:00 EDT 2022
A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis.
Immunology and cell biology
Zhang L,Feng X,Shen Y,Wang Y,Liu Z,Ma Y,Gu Y,Guo G,Duan L,Lu L,Liang Y,Lawrence T,Huang R
45-0193-82 was used in Flow cytometry/Cell sorting to demonstrate that the ZsGreen-expressing YUMM1.7 melanoma model provides a valuable tool for the study of phagocytosis in vivo.
Sat Oct 01 00:00:00 EDT 2022
Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome.
Cell host & microbe
Dallari S,Heaney T,Rosas-Villegas A,Neil JA,Wong SY,Brown JJ,Urbanek K,Herrmann C,Depledge DP,Dermody TS,Cadwell K
45-0193-82 was used in Flow cytometry/Cell sorting to expand an understanding of the immune space occupied by the enteric virome and underscore the importance of viral exposure events.
Wed Jun 09 00:00:00 EDT 2021
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
45-0193-82 was used in Flow Cytometry to elucidate the molecular mechanisms regulating T follicular helper cells.
Thu Apr 01 00:00:00 EDT 2021
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity.
Cellular & molecular immunology
Huang X,Hao S,Liu J,Huang Y,Liu M,Xiao C,Wang Y,Pei S,Yu T,Xu J,Wang H,Dai D,Su X,Xiao Y
45-0193-82 was used in Flow Cytometry to elucidate the molecular mechanisms regulating T follicular helper cells.
Thu Apr 01 00:00:00 EDT 2021
Functional human IgA targets a conserved site on malaria sporozoites.
Science translational medicine
Tan J,Cho H,Pholcharee T,Pereira LS,Doumbo S,Doumtabe D,Flynn BJ,Schön A,Kanatani S,Aylor SO,Oyen D,Vistein R,Wang L,Dillon M,Skinner J,Peterson M,Li S,Idris AH,Molina-Cruz A,Zhao M,Olano LR,Lee PJ,Roth A,Sinnis P,Barillas-Mury C,Kayentao K,Ongoiba A,Francica JR,Traore B,Wilson IA,Seder RA,Crompton PD
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.
PLoS pathogens
Niemeyer BF,Sanford B,Gibson JE,Berger JN,Oko LM,Medina E,Clambey ET,van Dyk LF
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice.
European journal of immunology
Paiva RS,Ramos CV,Azenha SR,Alves C,Basto AP,Graca L,Martins VC
45-0193-82 was used in Flow Cytometry to show that Ppic is dispensable for myeloid cells, platelets, erythrocytes, αβ and γδ T lymphocytes in vivo in the steady state, while being involved in B and iNKT cell differentiation.
Sun Aug 01 00:00:00 EDT 2021
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Jan 24 00:00:00 EST 2022
Regulatory B Cells (Bregs) Inhibit Osteoclastogenesis and Play a Potential Role in Ameliorating Ovariectomy-Induced Bone Loss.
Frontiers in immunology
Sapra L,Bhardwaj A,Mishra PK,Garg B,Verma B,Mishra GC,Srivastava RK
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu Nov 04 00:00:00 EDT 2021
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.
PloS one
Trenevska I,Anderson AP,Bentley C,Hassanali T,Wiblin S,Maguire S,Pezzella F,Banham AH,Li D
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Sep 29 00:00:00 EDT 2021
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
eLife
Glassman CR,Su L,Majri-Morrison SS,Winkelmann H,Mo F,Li P,Pérez-Cruz M,Ho PP,Koliesnik I,Nagy N,Hnizdilova T,Picton LK,Kovar M,Bollyky P,Steinman L,Meyer E,Piehler J,Leonard WJ,Garcia KC
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue May 18 00:00:00 EDT 2021
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.
Developmental cell
Dege C,Fegan KH,Creamer JP,Berrien-Elliott MM,Luff SA,Kim D,Wagner JA,Kingsley PD,McGrath KE,Fehniger TA,Palis J,Sturgeon CM
45-0193 was used in Flow cytometry/Cell sorting to identify an extra-embryonic origin of potently cytotoxic NK cells, suggesting that ontogenic origin is a relevant factor in designing hPSC-derived adoptive immunotherapies.
Mon Apr 20 00:00:00 EDT 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia.
Stem cells international
Zhao AG,Shah K,Freitag J,Cromer B,Sumer H
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2020
Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.
Frontiers in immunology
Zhou B,Yang W,Li W,He L,Lu L,Zhang L,Liu Z,Wang Y,Chao T,Huang R,Gu Y,Jia T,Liu Q,Tian S,Pierre P,Maeda T,Liang Y,Kong E
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
CNS Immune Profiling in a Dengue Virus-Infected Immunocompetent Outbred ICR Mice Strain.
Frontiers in cellular and infection microbiology
Shen TJ,Chen CL,Jhan MK,Tseng PC,Lin CF
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu Jun 17 00:00:00 EDT 2021
Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.
PloS one
Parra M,Weitner M,Yang A,Akue A,Liu X,Schmidt T,Allman WR,Akkoyunlu M,Derrick SC
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells.
Immunity
Pokrovskii M,Hall JA,Ochayon DE,Yi R,Chaimowitz NS,Seelamneni H,Carriero N,Watters A,Waggoner SN,Littman DR,Bonneau R,Miraldi ER
45-0193 was used in Flow cytometry/Cell sorting to study regulatory interactions between transcription factors and genes within intestinal type 1, 2, and 3 innate lymphoid cells subsets.
Tue Jul 16 00:00:00 EDT 2019
Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence.
Molecular cell
Zhang H,Alsaleh G,Feltham J,Sun Y,Napolitano G,Riffelmacher T,Charles P,Frau L,Hublitz P,Yu Z,Mohammed S,Ballabio A,Balabanov S,Mellor J,Simon AK
45-0193 was used in Flow cytometry/Cell sorting to reveal an unexpected autophagy regulatory mechanism mediated by eIF5A at the translational level, which can be harnessed to reverse immune senescence in humans.
Thu Oct 03 00:00:00 EDT 2019
Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.
Frontiers in immunology
Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Aug 17 00:00:00 EDT 2020
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Scientific reports
Goldstein JM,Valido A,Lewandowski JP,Walker RG,Mills MJ,Messemer KA,Besseling P,Lee KH,Wattrus SJ,Cho M,Lee RT,Wagers AJ
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Dec 09 00:00:00 EST 2019
The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells.
Cell reports
Araujo LP,Maricato JT,Guereschi MG,Takenaka MC,Nascimento VM,de Melo FM,Quintana FJ,Brum PC,Basso AS
45-0193-82 was used in Flow Cytometry to uncover a suppressive role for the SNS in CNS autoimmunity while they identify potential targets for therapeutic intervention.
Tue Sep 17 00:00:00 EDT 2019
Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells.
Autophagy
Oh DS,Lee HK
45-0193-82 was used in Flow Cytometry to demonstrate that Atg5 is required for proper antigen phagocytosis and presentation to MHC class II via modulation of CD36 in dendritic cells and may be a future therapeutic target for anti-tumor therapy.
Sun Dec 01 00:00:00 EST 2019
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Nature communications
Luu M,Pautz S,Kohl V,Singh R,Romero R,Lucas S,Hofmann J,Raifer H,Vachharajani N,Carrascosa LC,Lamp B,Nist A,Stiewe T,Shaul Y,Adhikary T,Zaiss MM,Lauth M,Steinhoff U,Visekruna A
45-0193-82 was used in Flow Cytometry to show that pentanoate, a physiologically abundant SCFA, is a potent regulator of immunometabolism.
Fri Feb 15 00:00:00 EST 2019
Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis.
Scientific reports
Brichacek AL,Benkovic SA,Chakraborty S,Nwafor DC,Wang W,Jun S,Dakhlallah D,Geldenhuys WJ,Pinkerton AB,Millán JL,Brown CM
45-0193-82 was used in Flow Cytometry to demonstrate a novel role for TNAP activity in shaping the dynamic interactions within the brain-immune axis.
Wed Dec 11 00:00:00 EST 2019
Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production.
PloS one
Mathä L,Shim H,Steer CA,Yin YH,Martinez-Gonzalez I,Takei F
45-0193-82 was used in Flow Cytometry to suggest that female ILC2s are more readily activated than male ILC2s due to their gene expression at the naïve state, which is potentially influenced by the lung environment.
Mon Dec 16 00:00:00 EST 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Cancer discovery
Dominguez PM,Ghamlouch H,Rosikiewicz W,Kumar P,Béguelin W,Fontán L,Rivas MA,Pawlikowska P,Armand M,Mouly E,Torres-Martin M,Doane AS,Calvo Fernandez MT,Durant M,Della-Valle V,Teater M,Cimmino L,Droin N,Tadros S,Motanagh S,Shih AH,Rubin MA,Tam W,Aifantis I,Levine RL,Elemento O,Inghirami G,Green MR,Figueroa ME,Bernard OA,Aoufouchi S,Li S,Shaknovich R,Melnick AM
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.
Molecular cell
Ribeiro de Almeida C,Dhir S,Dhir A,Moghaddam AE,Sattentau Q,Meinhart A,Proudfoot NJ
45-0193 was used in Flow cytometry/Cell sorting to provide evidence for how S-region transcripts interconvert between G4 and R-loop structures to promote IgH class switch recombination.
Thu May 17 00:00:00 EDT 2018
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.
Journal of autoimmunity
Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2018
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.
Frontiers in immunology
Liu R,King A,Bouillet P,Tarlinton DM,Strasser A,Heierhorst J
45-0193 was used in Flow cytometry/Cell sorting to indicate that BIM regulates B cell homeostasis predominantly by limiting the life span of non-activated mature B cells.
Wed May 01 00:00:00 EDT 2019
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart.
Frontiers in cardiovascular medicine
Sarkar A,Shukla SK,Alqatawni A,Kumar A,Addya S,Tsygankov AY,Rafiq K
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Dec 06 00:00:00 EST 2021
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation.
Stem cell reports
Kauts ML,Rodriguez-Seoane C,Kaimakis P,Mendes SC,Cortés-Lavaud X,Hill U,Dzierzak E
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Jan 09 00:00:00 EST 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Mon Mar 19 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
Nature
Kim S,Kim H,Yim YS,Ha S,Atarashi K,Tan TG,Longman RS,Honda K,Littman DR,Choi GB,Huh JR
45-0193 was used in Flow cytometry/Cell sorting to suggest that defined gut commensal bacteria with a propensity to induce TH17 cells may increase the risk of neurodevelopmental disorders in the offspring of pregnant mothers undergoing immune system activation owing to infections or autoinflammatory syndromes.
Thu Sep 28 00:00:00 EDT 2017
A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.
The Journal of clinical investigation
Chang AY,Dao T,Gejman RS,Jarvis CA,Scott A,Dubrovsky L,Mathias MD,Korontsvit T,Zakhaleva V,Curcio M,Hendrickson RC,Liu C,Scheinberg DA
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Fri Jun 30 00:00:00 EDT 2017
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo.
Journal of virology
Ding Q,von Schaewen M,Hrebikova G,Heller B,Sandmann L,Plaas M,Ploss A
45-0193 was used in Flow cytometry/Cell sorting to demonstrate that minimally humanized mice develop normally, express the modified genes at physiological levels, and support Hepatitis C virus uptake.
Wed Feb 15 00:00:00 EST 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Wagner JM,Jaurich H,Wallner C,Abraham S,Becerikli M,Dadras M,Harati K,Duhan V,Khairnar V,Lehnhardt M,Behr B
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy.
Oncoimmunology
Zafar S,Parviainen S,Siurala M,Hemminki O,Havunen R,Tähtinen S,Bramante S,Vassilev L,Wang H,Lieber A,Hemmi S,de Gruijl T,Kanerva A,Hemminki A
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Oct 17 00:00:00 EDT 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
45-0193 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 EDT 2016
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Cancer discovery
Pylayeva-Gupta Y,Das S,Handler JS,Hajdu CH,Coffre M,Koralov SB,Bar-Sagi D
45-0193 was used in Flow cytometry/Cell sorting to identify a previously unrecognised role for IL35-producing CD1d(hi)CD5(+) B cells in the pathogenesis of pancreatic cancer.
Tue Mar 01 00:00:00 EST 2016
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology
Dou DR,Calvanese V,Sierra MI,Nguyen AT,Minasian A,Saarikoski P,Sasidharan R,Ramirez CM,Zack JA,Crooks GM,Galic Z,Mikkola HK
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jun 01 00:00:00 EDT 2016
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.
The Journal of experimental medicine
Drennan MB,Govindarajan S,Verheugen E,Coquet JM,Staal J,McGuire C,Taghon T,Leclercq G,Beyaert R,van Loo G,Lambrecht BN,Elewaut D
45-0193 was used in Flow cytometry/Cell sorting to show that negative regulation of TCR signalling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
Mon Sep 19 00:00:00 EDT 2016
CNS accumulation of regulatory B cells is VLA-4-dependent.
Neurology(R) neuroimmunology & neuroinflammation
Lehmann-Horn K,Sagan SA,Winger RC,Spencer CM,Bernard CC,Sobel RA,Zamvil SS
45-0193 was used in Immunocytochemistry to demonstrate that accumulation of Breg in the CNS is dependent on VLA-4.
Fri Apr 01 00:00:00 EDT 2016
CNS accumulation of regulatory B cells is VLA-4-dependent.
Neurology(R) neuroimmunology & neuroinflammation
Lehmann-Horn K,Sagan SA,Winger RC,Spencer CM,Bernard CC,Sobel RA,Zamvil SS
45-0193 was used in Immunocytochemistry to demonstrate that accumulation of Breg in the CNS is dependent on VLA-4.
Fri Apr 01 00:00:00 EDT 2016
IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing.
The Journal of investigative dermatology
Rak GD,Osborne LC,Siracusa MC,Kim BS,Wang K,Bayat A,Artis D,Volk SW
45-0193 was used in Flow cytometry/Cell sorting to demonstrate that cutaneous injury promotes an IL-33-dependent group 2 ILC response and that abrogation of this response can impair efficient wound closure.
Mon Feb 01 00:00:00 EST 2016
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Grodeland G,Fredriksen AB,Løset GÅ,Vikse E,Fugger L,Bogen B
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
Protein Translation Activity: A New Measure of Host Immune Cell Activation.
Journal of immunology (Baltimore, Md. : 1950)
Seedhom MO,Hickman HD,Wei J,David A,Yewdell JW
45-0193 was used in Flow cytometry/Cell sorting to describe the in vivo ribopuromycylation method.
Mon Aug 15 00:00:00 EDT 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jul 27 00:00:00 EDT 2016
Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.
Oncotarget
Weiss JM,Robinet M,Aricha R,Cufi P,Villeret B,Lantner F,Shachar I,Fuchs S,Souroujon MC,Berrih-Aknin S,Le Panse R
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2016
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Scientific reports
Xiong J,Zhou MF,Wang YD,Chen LP,Xu WF,Wang YD,Deng F,Liu SD
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Fri Sep 23 00:00:00 EDT 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
45-0193 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
A small-molecule inhibitor of SHIP1 reverses age- and diet-associated obesity and metabolic syndrome.
JCI insight
Srivastava N,Iyer S,Sudan R,Youngs C,Engelman RW,Howard KT,Russo CM,Chisholm JD,Kerr WG
45-0193 was used in Flow cytometry/Cell sorting to investigate how SHIPi represents an approach that permits control of obesity and diet-induced metabolic syndrome without apparent toxicity.
Thu Jul 21 00:00:00 EDT 2016
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells.
Aging
Hall BM,Balan V,Gleiberman AS,Strom E,Krasnov P,Virtuoso LP,Rydkina E,Vujcic S,Balan K,Gitlin I,Leonova K,Polinsky A,Chernova OB,Gudkov AV
45-0193 was used in Flow cytometry/Cell sorting to investigate the role of p16(Ink4a)/Β-gal(pH6)-positive macrophages in aging, which previously was attributed solely to senescent cells.
Fri Jul 01 00:00:00 EDT 2016
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Nature
Canver MC,Smith EC,Sher F,Pinello L,Sanjana NE,Shalem O,Chen DD,Schupp PG,Vinjamur DS,Garcia SP,Luc S,Kurita R,Nakamura Y,Fujiwara Y,Maeda T,Yuan GC,Zhang F,Orkin SH,Bauer DE
45-0193 was used in Flow cytometry/Cell sorting to develop pooled CRISPR-Cas9 guide RNA libraries to perform in situ saturating mutagenesis of human and mouse enhancers.
Thu Nov 12 00:00:00 EST 2015
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.
Nature
Brestoff JR,Kim BS,Saenz SA,Stine RR,Monticelli LA,Sonnenberg GF,Thome JJ,Farber DL,Lutfy K,Seale P,Artis D
45-0193 was used in Flow cytometry/Cell sorting to study how ILC2s can regulate adipose function and metabolic homeostasis.
Thu Mar 12 00:00:00 EDT 2015
Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.
Cancer cell
Wu SC,Li LS,Kopp N,Montero J,Chapuy B,Yoda A,Christie AL,Liu H,Christodoulou A,van Bodegom D,van der Zwet J,Layer JV,Tivey T,Lane AA,Ryan JA,Ng SY,DeAngelo DJ,Stone RM,Steensma D,Wadleigh M,Harris M,Mandon E,Ebel N,Andraos R,Romanet V,Dölemeyer A,Sterker D,Zender M,Rodig SJ,Murakami M,Hofmann F,Kuo F,Eck MJ,Silverman LB,Sallan SE,Letai A,Baffert F,Vangrevelinghe E,Radimerski T,Gaul C,Weinstock DM
45-0193 was used in Flow cytometry/Cell sorting to support the testing of type II JAK2 inhibition in patients with JAK2-dependent leukemias and other disorders.
Mon Jul 13 00:00:00 EDT 2015
Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.
The Journal of clinical investigation
Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS
45-0193 was used in Flow cytometry/Cell sorting to identify a membrane-initiated pathway that is triggered by apoptotic cells to enhance ABCA1 within engulfing phagocytes.
Wed Jul 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity.
Annals of neurology
Lehmann-Horn K,Sagan SA,Bernard CC,Sobel RA,Zamvil SS
45-0193 was used in Flow cytometry/Cell sorting to report that the selective inhibition of VLA-4 expression on B cells impedes CNS accumulation of B cells, and recruitment of Th17 cells and macrophages.
Fri May 01 00:00:00 EDT 2015
Role of caveolin-3 in lymphocyte activation.
Life sciences
Tran C,Stary CM,Schilling JM,Bentley B,Patel HH,Roth DM
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Thu Jan 15 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Tue Sep 15 00:00:00 EDT 2015
HGF Gene Modification in Mesenchymal Stem Cells Reduces Radiation-Induced Intestinal Injury by Modulating Immunity.
PloS one
Wang H,Sun RT,Li Y,Yang YF,Xiao FJ,Zhang YK,Wang SX,Sun HY,Zhang QW,Wu CT,Wang LS
45-0193 was used in Flow cytometry/Cell sorting to evaluate the therapeutic effect of hepatocyte growth factor-gene-modified MSCs on radiation-induced intestinal injury.
Tue Jan 26 00:00:00 EST 2016
Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
The Journal of biological chemistry
Motozono C,Pearson JA,De Leenheer E,Rizkallah PJ,Beck K,Trimby A,Sewell AK,Wong FS,Cole DK
45-0193 was used in Flow cytometry/Cell sorting to study how distortion in the MHC class I binding groove can accommodate extra C-terminal peptide residues..
Fri Jul 31 00:00:00 EDT 2015
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation.
Science translational medicine
Beale J,Jayaraman A,Jackson DJ,Macintyre JDR,Edwards MR,Walton RP,Zhu J,Man Ching Y,Shamji B,Edwards M,Westwick J,Cousins DJ,Yi Hwang Y,McKenzie A,Johnston SL,Bartlett NW
45-0193 was used in Flow cytometry/Cell sorting to demonstrate asthmatic epithelial cells have an increased intrinsic capacity for expression of a pro-type 2 cytokine in response to a viral infection.
Wed Oct 01 00:00:00 EDT 2014
Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.
Antioxidants & redox signaling
Kelkka T,Kienhöfer D,Hoffmann M,Linja M,Wing K,Sareila O,Hultqvist M,Laajala E,Chen Z,Vasconcelos J,Neves E,Guedes M,Marques L,Krönke G,Helminen M,Kainulainen L,Olofsson P,Jalkanen S,Lahesmaa R,Souto-Carneiro MM,Holmdahl R
45-0193 was used in Flow cytometry/Cell sorting to explore the connection between reactive oxygen species deficiencies and increased susceptibility to autoimmunity.
Mon Dec 01 00:00:00 EST 2014
Oral combined therapy with probiotics and alloantigen induces B cell-dependent long-lasting specific tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Mercadante AC,Perobelli SM,Alves AP,Gonçalves-Silva T,Mello W,Gomes-Santos AC,Miyoshi A,Azevedo V,Faria AM,Bonomo A
45-0193 was used in Flow cytometry/Cell sorting to suggest that combined therapy is a promising strategy for prevention of GVHD with preservation of graft-versus-leukemia in allogenic HSCT.
Sat Feb 15 00:00:00 EST 2014
Genome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.
PLoS pathogens
Caignard G,Leiva-Torres GA,Leney-Greene M,Charbonneau B,Dumaine A,Fodil-Cornu N,Pyzik M,Cingolani P,Schwartzentruber J,Dupaul-Chicoine J,Guo H,Saleh M,Veillette A,Lathrop M,Blanchette M,Majewski J,Pearson A,Vidal SM
45-0193 was used in Flow cytometry/Cell sorting to identify host factors involved in HSV-1 and herpes simplex encephalitis susceptibility in an in vivo HSV-1 infectious model.
Sun Sep 01 00:00:00 EDT 2013
The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.
PLoS pathogens
Wagner FM,Brizic I,Prager A,Trsan T,Arapovic M,Lemmermann NA,Podlech J,Reddehase MJ,Lemnitzer F,Bosse JB,Gimpfl M,Marcinowski L,MacDonald M,Adler H,Koszinowski UH,Adler B
45-0193 was used in Flow cytometry/Cell sorting to demonstrate that MCK-2 has a dual role in cytomegalovirus infection, as a regulator of immune response and also in promoting viral entry into cells.
Tue Feb 18 00:00:00 EST 2014
Cellular-FLIP, Raji isoform (c-FLIP R) modulates cell death induction upon T-cell activation and infection.
European journal of immunology
Telieps T,Ewald F,Gereke M,Annemann M,Rauter Y,Schuster M,Ueffing N,von Smolinski D,Gruber AD,Bruder D,Schmitz I
45-0193 was used in Flow cytometry/Cell sorting to study the induction of endogenous murine cellular-FLIPR in activated lymphocytes.
Sat Jun 01 00:00:00 EDT 2013
Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.
The Journal of biological chemistry
Patnode ML,Cheng CW,Chou CC,Singer MS,Elin MS,Uchimura K,Crocker PR,Khoo KH,Rosen SD
45-0193 was used in Flow cytometry/Cell sorting to investigate whether keratan sulfate galactose 6-O-sulfotransferase and chondroitin 6-O-sulfotransferase 1 are required for the generation of endogenous Siglec-F ligands.
Fri Sep 13 00:00:00 EDT 2013
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD19 monoclonal antibody (Product # 45-0193-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice.
PloS one
Donners MM,Wolfs IM,Stöger LJ,van der Vorst EP,Pöttgens CC,Heymans S,Schroen B,Gijbels MJ,de Winther MP
45-0193 was used in Flow cytometry/Cell sorting to investigate the role of miR155 in atherosclerosis in vivo, showing that miR155 deficiency enhances atherosclerosis and decreases plaque stability.
Thu Sep 13 00:00:00 EDT 2012
High-affinity memory B cells induced by conjugate vaccines against weak tumor antigens are vulnerable to nonconjugated antigen.
Blood
Savelyeva N,Shipton M,Suchacki A,Babbage G,Stevenson FK
45-0193 was used in Flow cytometry/Cell sorting to reveal a vulnerability in the immunity against weak tumour antigens conferred by conjugate vaccines.
Thu Jul 21 00:00:00 EDT 2011
